New compstatin variants through two de novo protein design frameworks (Q33858609)

29 July 2017

title

New compstatin variants through two de novo protein design frameworks (English)

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29 July 2017

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M L Bellows

1

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29 July 2017

H K Fung

2

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29 July 2017

M S Taylor

3

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29 July 2017

M S Taylor

4

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29 July 2017

C A Floudas

5

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29 July 2017

A López de Victoria

6

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29 July 2017

D Morikis

7

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29 July 2017

language of work or name

English

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publication date

1 May 2010

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29 July 2017

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29 July 2017

volume

98

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29 July 2017

issue

10

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29 July 2017

page(s)

2337-2346

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Biclustering via optimal re-ordering of data matrices in systems biology: rigorous methods and comparative studies

29 July 2017

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Mutations affecting the oligomerization interface of G-protein-coupled receptors revealed by a novel de novo protein design framework

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5 July 2018

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Structure of compstatin in complex with complement component C3c reveals a new mechanism of complement inhibition

5 July 2018

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Conformational analysis of compstatin analogues with molecular dynamics simulations in explicit water

5 July 2018

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5 July 2018

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CAPRI rounds 3-5 reveal promising successes and future challenges for RosettaDock

5 July 2018

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Ab initio prediction of the three-dimensional structure of a de novo designed protein: a double-blind case study

5 July 2018

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5 July 2018

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Improvement of the anti-C3 activity of compstatin using rational and combinatorial approaches

5 July 2018

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5 July 2018

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Studies of structure-activity relations of complement inhibitor compstatin.

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Structural aspects and design of low-molecular-mass complement inhibitors

5 July 2018

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De novo determination of protein backbone structure from residual dipolar couplings using Rosetta

5 July 2018

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The structural basis of compstatin activity examined by structure-function-based design of peptide analogs and NMR.

5 July 2018

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5 July 2018

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Structure and biology of complement protein C3, a connecting link between innate and acquired immunity

5 July 2018

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Native protein sequences are close to optimal for their structures

5 July 2018

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Binding kinetics, structure-activity relationship, and biotransformation of the complement inhibitor compstatin

5 July 2018

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5 July 2018

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Solution structure of Compstatin, a potent complement inhibitor

5 July 2018

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Torsion angle dynamics for NMR structure calculation with the new program DYANA

5 July 2018

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Inhibition of human complement by a C3-binding peptide isolated from a phage-displayed random peptide library.

5 July 2018

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5 July 2018

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A novel ensemble-based scoring and search algorithm for protein redesign and its application to modify the substrate specificity of the gramicidin synthetase a phenylalanine adenylation enzyme

29 October 2018

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Development of a quasi-dynamic pharmacophore model for anti-complement peptide analogues

29 October 2018

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Design and NMR characterization of active analogues of compstatin containing non-natural amino acids

29 October 2018

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Conformational interconversion in compstatin probed with molecular dynamics simulations

29 October 2018

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Prediction of beta-sheet topology and disulfide bridges in polypeptides.

29 October 2018

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Compstatin, a peptide inhibitor of complement, exhibits species-specific binding to complement component C3.

29 October 2018

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Essential role of the C5a receptor in E coli-induced oxidative burst and phagocytosis revealed by a novel lepirudin-based human whole blood model of inflammation

29 October 2018

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Ab initio prediction of helical segments in polypeptides.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872270

Antagonist inhibition curves and the measurement of dissociation constants

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872270

NMR evidence for multiple conformations in a highly helical model peptide.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872270

BIOCHEMISTRY: How Do Proteins Interact?

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872270

Compstatin inhibits complement and cellular activation in whole blood in two models of extracorporeal circulation

29 October 2018

1 reference

12 December 2020

Compstatin, a peptide inhibitor of C3, prolongs survival of ex vivo perfused pig xenografts

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12 December 2020

Effects of C-reactive protein and pentosan polysulphate on human complement activation

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12 December 2020

Integrated Computational and Experimental Approach for Lead Optimization and Design of Compstatin Variants with Improved Activity

1 reference

12 December 2020

Inhibition of Heparin/Protamine Complex-Induced Complement Activation by Compstatin in Baboons

1 reference

12 December 2020

Inhibitor of complement, Compstatin, prevents polymer-mediated Mac-1 up-regulation of human neutrophils independent of biomaterial type tested

1 reference

12 December 2020

10.1016/J.BPJ.2010.01.057

Identifiers

DOI

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29 July 2017

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29 July 2017

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