LGH00031, a novel ortho-quinonoid inhibitor of cell division cycle 25B, inhibits human cancer cells via ROS generation (Q33859003)

29 July 2017

title

LGH00031, a novel ortho-quinonoid inhibitor of cell division cycle 25B, inhibits human cancer cells via ROS generation (English)

1 reference

29 July 2017

Yu-bo Zhou

1

1 reference

29 July 2017

Xu Feng

2

1 reference

29 July 2017

Li-na Wang

3

1 reference

29 July 2017

Jun-qing Du

4

1 reference

29 July 2017

Yue-yang Zhou

5

1 reference

29 July 2017

Hai-ping Yu

6

1 reference

29 July 2017

Yi Zang

7

1 reference

29 July 2017

Jing-ya Li

8

1 reference

29 July 2017

Jia Li

9

1 reference

29 July 2017

publication date

1 September 2009

1 reference

Acta Pharmacologica Sinica

29 July 2017

published in

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29 July 2017

volume

30

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29 July 2017

issue

9

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29 July 2017

page(s)

1359-1368

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IRC-083864, a novel bis quinone inhibitor of CDC25 phosphatases active against human cancer cells

29 July 2017

cites work

1 reference

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Discovery and characterization of a novel inhibitor of CDC25B, LGH00045.

5 July 2018

1 reference

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CDC25A inhibition suppresses the growth and invasion of human hepatocellular carcinoma cells.

5 July 2018

1 reference

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What's new on CDC25 phosphatase inhibitors

5 July 2018

1 reference

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Cdc25 phosphatases: structure, specificity, and mechanism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085684

Synthesis of miltirone analogues as inhibitors of Cdc25 phosphatases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085684

The oxidative mechanism of action of ortho-quinone inhibitors of protein-tyrosine phosphatase alpha is mediated by hydrogen peroxide

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085684

Discovery and characterization of novel small molecule inhibitors of human Cdc25B dual specificity phosphatase

5 July 2018

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Discovery of a novel protein tyrosine phosphatase-1B inhibitor, KR61639: potential development as an antihyperglycemic agent

5 July 2018

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Overexpression of Cdc25B, an androgen receptor coactivator, in prostate cancer

5 July 2018

1 reference

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Role of the Cdc25A phosphatase in human breast cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085684

The cdc25B phosphatase is essential for the G2/M phase transition in human cells

5 July 2018

1 reference

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CDC25 phosphatases as potential human oncogenes

5 July 2018

1 reference

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Expression of CDC25 phosphatases in human gastric cancer.

5 July 2018

1 reference

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Induction of mammary gland hyperplasia in transgenic mice over-expressing human Cdc25B.

21 January 2018

1 reference

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Design and synthesis of dysidiolide analogs from vitamin D3: novel class of Cdc25A inhibitors.

21 January 2018

1 reference

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Inhibition of human tumor cell growth in vivo by an orally bioavailable inhibitor of CDC25 phosphatases.

21 January 2018

1 reference

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Catalytic inactivation of protein tyrosine phosphatase CD45 and protein tyrosine phosphatase 1B by polyaromatic quinones

21 January 2018

1 reference

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Sulfur-centered radical formation from the antioxidant dihydrolipoic acid

21 January 2018

1 reference

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Redox regulation of Cdc25B by cell-active quinolinediones

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085684

Increased susceptibility to carcinogen-induced mammary tumors in MMTV-Cdc25B transgenic mice

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19730430

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

PM-20, a novel inhibitor of Cdc25A, induces extracellular signal-regulated kinase 1/2 phosphorylation and inhibits hepatocellular carcinoma growth in vitro and in vivo

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19730430

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Expression of the cdc25B gene as a prognosis marker in non-small cell lung cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19730430

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/APS.2009.131

1 reference

Dimensions Publication ID

29 July 2017

0 references

1 reference

29 July 2017

1 reference