Distinct roles of Cdc42 in thymopoiesis and effector and memory T cell differentiation (Q33859452)

29 July 2017

title

Distinct roles of Cdc42 in thymopoiesis and effector and memory T cell differentiation (English)

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29 July 2017

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9

H Leighton Grimes

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29 July 2017

David Hildeman

10

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Marsha Wills-Karp

8

object named as

Marsha Wills-Karp

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29 July 2017

Fukun Guo

1

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29 July 2017

Shuangmin Zhang

2

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29 July 2017

Pulak Tripathi

3

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29 July 2017

Jochen Mattner

4

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29 July 2017

James Phelan

5

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29 July 2017

Alyssa Sproles

6

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29 July 2017

Jun Mo

7

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29 July 2017

Yi Zheng

11

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29 July 2017

language of work or name

English

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publication date

24 March 2011

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29 July 2017

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29 July 2017

volume

6

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29 July 2017

issue

3

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29 July 2017

page(s)

e18002

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Creative Commons Attribution 4.0 International

29 July 2017

copyright license

start time

24 March 2011

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Signaling role of Cdc42 in regulating mammalian physiology

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Coordination of IL-7 receptor and T-cell receptor signaling by cell-division cycle 42 in T-cell homeostasis.

5 July 2018

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Generating diversity: transcriptional regulation of effector and memory CD8 T-cell differentiation

5 July 2018

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The TCR-mediated signaling pathways that control the direction of helper T cell differentiation

5 July 2018

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Autoimmune disease triggered by infection with alphaproteobacteria

5 July 2018

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Critical requirement for the Wiskott-Aldrich syndrome protein in Th2 effector function

5 July 2018

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Rho GTPase Cdc42 is essential for B-lymphocyte development and activation.

5 July 2018

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T cell antigen receptor signaling and immunological synapse stability require myosin IIA

5 July 2018

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Generation and maintenance of memory CD4(+) T Cells

5 July 2018

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5 July 2018

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Rac GTPases play critical roles in early T-cell development

5 July 2018

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Control of cytokine gene transcription in Th1 and Th2 cells.

5 July 2018

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Rac GTPase isoforms Rac1 and Rac2 play a redundant and crucial role in T-cell development.

5 July 2018

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How regulatory T cells work

5 July 2018

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Liver autoimmunity triggered by microbial activation of natural killer T cells

5 July 2018

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Rapid culling of the CD4+ T cell repertoire in the transition from effector to memory

5 July 2018

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Signal initiation in T-cell receptor microclusters

5 July 2018

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Immunological decision-making: how does the immune system decide to mount a helper T-cell response?

5 July 2018

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Cdc42 critically regulates the balance between myelopoiesis and erythropoiesis

5 July 2018

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SLAT regulates Th1 and Th2 inflammatory responses by controlling Ca2+/NFAT signaling

5 July 2018

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Bim/Bcl-2 balance is critical for maintaining naive and memory T cell homeostasis

5 July 2018

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Rho GTPases and their regulators in neuronal functions and development

5 July 2018

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Rho GTPase Cdc42 coordinates hematopoietic stem cell quiescence and niche interaction in the bone marrow

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063799

RhoH is important for positive thymocyte selection and T-cell receptor signaling

5 July 2018

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RhoH GTPase recruits and activates Zap70 required for T cell receptor signaling and thymocyte development

5 July 2018

1 reference

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Gene targeting of Cdc42 and Cdc42GAP affirms the critical involvement of Cdc42 in filopodia induction, directed migration, and proliferation in primary mouse embryonic fibroblasts

5 July 2018

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T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063799

Specific patterns of Cdc42 activity are related to distinct elements of T cell polarization

5 July 2018

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Cdc42 is not essential for filopodium formation, directed migration, cell polarization, and mitosis in fibroblastoid cells

5 July 2018

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What is the importance of the immunological synapse?

5 July 2018

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Paradoxical roles of IFN-gamma in models of Th1-mediated autoimmunity

5 July 2018

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The regulation of actin remodeling during T-cell-APC conjugate formation

5 July 2018

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T cell receptor signaling precedes immunological synapse formation

5 July 2018

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The interaction between Cdc42 and WASP is required for SDF-1-induced T-lymphocyte chemotaxis.

5 July 2018

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Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice

5 July 2018

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Regulation of naive T cell differentiation by varying the potency of TCR signal transduction

5 July 2018

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Cdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity

5 July 2018

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The JNK pathway regulates the In vivo deletion of immature CD4(+)CD8(+) thymocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063799

Regulation of the polarization of T cells toward antigen-presenting cells by Ras-related GTPase CDC42

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063799

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063799

Cell type-specific functions of Rho GTPases revealed by gene targeting in mice.

5 July 2018

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Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction

21 January 2018

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Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018002

An orally active Th1/Th2 balance modulator, M50367, suppresses Th2 differentiation of naı̈ve Th cell in vitro

21 January 2018

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12 December 2020

Strong TCR signaling, TLR ligands, and cytokine redundancies ensure robust development of type 1 effector T cells

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12 December 2020

Rho GTPase CDC42 regulates directionality and random movement via distinct MAPK pathways in neutrophils

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12 December 2020

Expression of activated CDC42 induces T cell apoptosis in thymus and peripheral lymph organs via different pathways

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The pathogenesis of primary biliary cirrhosis

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12 December 2020

10.1371/JOURNAL.PONE.0018002

Identifiers

DOI

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29 July 2017

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29 July 2017

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