Non-invasive drug delivery to the human brain using endogenous blood-brain barrier transport systems (Q33861126)

29 July 2017

Non-invasive drug delivery to the human brain using endogenous blood-brain barrier transport systems (English)

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29 July 2017

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29 July 2017

1 February 1999

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Pharmaceutical science & technology today

29 July 2017

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29 July 2017

2

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29 July 2017

2

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29 July 2017

49-59

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CNS drug design based on principles of blood-brain barrier transport

29 July 2017

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https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900117-5

7 January 2021

Drug delivery to the brain

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https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900117-5

7 January 2021

Brain-targeted delivery of a leucine-enkephalin analogue by retrometabolic design.

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900117-5

7 January 2021

N-docosahexaenoyl, 3 hydroxytyramine: a dopaminergic compound that penetrates the blood-brain barrier and suppresses appetite

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900117-5

7 January 2021

Pharmacokinetics of chlorambucil-tertiary butyl ester, a lipophilic chlorambucil derivative that achieves and maintains high concentrations in brain

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https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900117-5

7 January 2021

Transport of metabolic substrates through the blood-brain barrier.

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https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900117-5

7 January 2021

In vivo demonstration of subcellular localization of anti-transferrin receptor monoclonal antibody-colloidal gold conjugate in brain capillary endothelium

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900117-5

7 January 2021

Transport of [125I]transferrin through the rat blood-brain barrier

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https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900117-5

7 January 2021

Nutrition, somatomedins, and the brain

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https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900117-5

7 January 2021

Anti-transferrin receptor antibody and antibody-drug conjugates cross the blood-brain barrier

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https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900117-5

7 January 2021

Human insulin receptor monoclonal antibody undergoes high affinity binding to human brain capillaries in vitro and rapid transcytosis through the blood-brain barrier in vivo in the primate

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900117-5

7 January 2021

Drug targeting of a peptide radiopharmaceutical through the primate blood-brain barrier in vivo with a monoclonal antibody to the human insulin receptor

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https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900117-5

7 January 2021

Human blood-brain barrier insulin receptor

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https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900117-5

7 January 2021

Blood-brain barrier: interface between internal medicine and the brain

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900117-5

7 January 2021

Differential expression of 53- and 45-kDa brain capillary-specific proteins by brain capillary endothelium and choroid plexus in vivo and by brain capillary endothelium in tissue culture

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900117-5

7 January 2021

Transport of human recombinant brain-derived neurotrophic factor (BDNF) through the rat blood-brain barrier in vivo using vector-mediated peptide drug delivery

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900117-5

7 January 2021

Disruption of the low affinity receptor-binding site in NGF allows neuronal survival and differentiation by binding to the trk gene product

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900117-5

7 January 2021

Carboxyl-directed pegylation of brain-derived neurotrophic factor markedly reduces systemic clearance with minimal loss of biologic activity

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https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900117-5

7 January 2021

Classical electrostatics in biology and chemistry

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https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900117-5

7 January 2021

Combined use of carboxyl-directed protein pegylation and vector-mediated blood-brain barrier drug delivery system optimizes brain uptake of brain-derived neurotrophic factor following intravenous administration.

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900117-5

7 January 2021

Characterization of the relaxant effects of vasoactive intestinal peptide (VIP) and PHI on isolated brain arteries.

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https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900117-5

7 January 2021

Pharmacologic effects in vivo in brain by vector-mediated peptide drug delivery.

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https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900117-5

7 January 2021

Pharmacology of neurotrophic factors

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https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900117-5

7 January 2021

Models for studying long-term recovery following forebrain ischemia in the rat. 2. A 2-vessel occlusion model.

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900117-5

7 January 2021

Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900117-5

7 January 2021

Radiolabeling of epidermal growth factor with 99mTc and in vivo localization following intracerebral injection into normal and glioma-bearing rats.

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https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900117-5

7 January 2021

Kinetic analysis of the elimination process of human epidermal growth factor (hEGF) in rats

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900117-5

7 January 2021

Opening the blood-brain and blood-tumor barriers in experimental rat brain tumors: the effect of intracarotid hyperosmolar mannitol on capillary permeability and blood flow.

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900117-5

7 January 2021

Reversible in vitro growth of Alzheimer disease beta-amyloid plaques by deposition of labeled amyloid peptide

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900117-5

7 January 2021

Vector-mediated delivery of 125I-labeled beta-amyloid peptide A beta 1-40 through the blood-brain barrier and binding to Alzheimer disease amyloid of the A beta 1-40/vector complex

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900117-5

7 January 2021

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900117-5

1 reference

7 January 2021

Pre-targeted immunodetection in glioma patients: tumour localization and single-photon emission tomography imaging of [99mTc]PnAO-biotin.

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900117-5

7 January 2021

Avidin and streptavidin

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900117-5

7 January 2021

Brain drug delivery of small molecules using immunoliposomes

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https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900117-5

7 January 2021

The vascularization of the human cerebellar cortex.

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900117-5

7 January 2021

10.1016/S1461-5347(98)00117-5

Identifiers

DOI

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29 July 2017

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PubMed ID

10234207