The Toxoplasma pseudokinase ROP5 forms complexes with ROP18 and ROP17 kinases that synergize to control acute virulence in mice (Q33861156)

29 July 2017

title

The Toxoplasma pseudokinase ROP5 forms complexes with ROP18 and ROP17 kinases that synergize to control acute virulence in mice (English)

1 reference

29 July 2017

6

L David Sibley

1 reference

29 July 2017

Ronald D Etheridge

1

1 reference

29 July 2017

Aditi Alaganan

2

1 reference

29 July 2017

Keliang Tang

3

1 reference

29 July 2017

Hua Jane Lou

4

1 reference

29 July 2017

Benjamin E Turk

5

1 reference

29 July 2017

language of work or name

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1 May 2014

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29 July 2017

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29 July 2017

volume

15

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29 July 2017

issue

5

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29 July 2017

page(s)

537-550

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Toxoplasma GRA7 effector increases turnover of immunity-related GTPases and contributes to acute virulence in the mouse

29 July 2017

cites work

1 reference

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IRG and GBP host resistance factors target aberrant, "non-self" vacuoles characterized by the missing of "self" IRGM proteins

5 July 2018

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Guanylate-binding protein 1 (Gbp1) contributes to cell-autonomous immunity against Toxoplasma gondii

5 July 2018

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Murine guanylate binding protein 2 (mGBP2) controls Toxoplasma gondii replication

5 July 2018

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The polymorphic pseudokinase ROP5 controls virulence in Toxoplasma gondii by regulating the active kinase ROP18

5 July 2018

1 reference

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IFN-inducible GTPases in host cell defense

5 July 2018

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Modulation of innate immunity by Toxoplasma gondii virulence effectors

5 July 2018

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A Toxoplasma gondii pseudokinase inhibits host IRG resistance proteins

5 July 2018

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5 July 2018

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The IRG protein-based resistance mechanism in mice and its relation to virulence in Toxoplasma gondii

5 July 2018

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The secreted kinase ROP18 defends Toxoplasma's border

5 July 2018

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A Conserved Non-canonical Motif in the Pseudoactive Site of the ROP5 Pseudokinase Domain Mediates Its Effect on Toxoplasma Virulence

5 July 2018

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ATF6beta is a host cellular target of the Toxoplasma gondii virulence factor ROP18.

5 July 2018

1 reference

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Virulence differences in Toxoplasma mediated by amplification of a family of polymorphic pseudokinases

5 July 2018

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Polymorphic family of injected pseudokinases is paramount in Toxoplasma virulence

5 July 2018

1 reference

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Phosphorylation of mouse immunity-related GTPase (IRG) resistance proteins is an evasion strategy for virulent Toxoplasma gondii

5 July 2018

1 reference

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Phosphorylation of immunity-related GTPases by a Toxoplasma gondii-secreted kinase promotes macrophage survival and virulence

5 July 2018

1 reference

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Integrative genomic approaches highlight a family of parasite-specific kinases that regulate host responses

5 July 2018

1 reference

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Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole

5 July 2018

1 reference

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A helical membrane-binding domain targets the Toxoplasma ROP2 family to the parasitophorous vacuole

5 July 2018

1 reference

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Virulent Toxoplasma gondii evade immunity-related GTPase-mediated parasite vacuole disruption within primed macrophages

5 July 2018

1 reference

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The Toxoplasma gondii dense granule protein GRA7 is phosphorylated upon invasion and forms an unexpected association with the rhoptry proteins ROP2 and ROP4

5 July 2018

1 reference

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Population structure of Toxoplasma gondii: clonal expansion driven by infrequent recombination and selective sweeps

5 July 2018

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Control of IFN-gamma-mediated host resistance to intracellular pathogens by immunity-related GTPases (p47 GTPases).

5 July 2018

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Determining protein kinase substrate specificity by parallel solution-phase assay of large numbers of peptide substrates

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086214

Polymorphic secreted kinases are key virulence factors in toxoplasmosis

5 July 2018

1 reference

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A secreted serine-threonine kinase determines virulence in the eukaryotic pathogen Toxoplasma gondii

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086214

Proteomic analysis of rhoptry organelles reveals many novel constituents for host-parasite interactions in Toxoplasma gondii

5 July 2018

1 reference

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Composite genome map and recombination parameters derived from three archetypal lineages of Toxoplasma gondii

5 July 2018

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Identification of quantitative trait loci controlling acute virulence in Toxoplasma gondii

5 July 2018

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Toxoplasma evacuoles: a two-step process of secretion and fusion forms the parasitophorous vacuole

5 July 2018

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The tandem affinity purification (TAP) method: a general procedure of protein complex purification

5 July 2018

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Pathogen-specific loss of host resistance in mice lacking the IFN-gamma-inducible gene IGTP

5 July 2018

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Effector cells of both nonhemopoietic and hemopoietic origin are required for interferon (IFN)-gamma- and tumor necrosis factor (TNF)-alpha-dependent host resistance to the intracellular pathogen, Toxoplasma gondii

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086214

Molecular characterization of a 65-kilodalton Toxoplasma gondii antigen expressed abundantly in the matrix of tissue cysts

5 July 2018

1 reference

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Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086214

Mouse model of X-linked chronic granulomatous disease, an inherited defect in phagocyte superoxide production

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086214

Tight control of transcription in Toxoplasma gondii using an alternative tet repressor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086214

Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24832449

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A Cluster of Interferon-γ-Inducible p65 GTPases Plays a Critical Role in Host Defense against Toxoplasma gondii

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24832449

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CHOM.2014.04.002

1 reference

29 July 2017

1 reference

29 July 2017

1 reference