Mitochondrial membrane potential and neuronal glutamate excitotoxicity: mortality and millivolts (Q33863123)

29 July 2017

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title

Mitochondrial membrane potential and neuronal glutamate excitotoxicity: mortality and millivolts (English)

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29 July 2017

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Nicholls DG

1

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PubMed ID

10717676

29 July 2017

Ward MW

series ordinal

2

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29 July 2017

1 April 2000

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29 July 2017

Trends in Neurosciences

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29 July 2017

23

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29 July 2017

166-174

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29 July 2017

4

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Pathobiology of ischaemic stroke: an integrated view

29 July 2017

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https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

The changing landscape of ischaemic brain injury mechanisms.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Mitochondria and neuronal glutamate excitotoxicity.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Mitochondrial depolarization in glutamate-stimulated neurons: an early signal specific to excitotoxin exposure

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Mitochondrial dysfunction is a primary event in glutamate neurotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Mitochondrial deenergization underlies neuronal calcium overload following a prolonged glutamate challenge

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Neurotoxic glutamate treatment of cultured cerebellar granule cells induces Ca2+ -dependent collapse of mitochondrial membrane potential and ultrastructural alterations of mitochondria.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Altered Ca2+ signaling and mitochondrial deficiencies in hippocampal neurons of trisomy 16 mice: a model of Down's syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Effects of oxidants and glutamate receptor activation on mitochondrial membrane potential in rat forebrain neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Mitochondrial transmembrane potential and free radical production in excitotoxic neurodegeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Contributions of mitochondria to animal physiology: from homeostatic sensor to calcium signalling and cell death

1 reference

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7 January 2021

Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Nitric oxide mediates glutamate-induced mitochondrial depolarization in rat cortical neurons.

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https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Glutamate-induced calcium transient triggers delayed calcium overload and neurotoxicity in rat hippocampal neurons

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7 January 2021

Source specificity of early calcium neurotoxicity in cultured embryonic spinal neurons

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7 January 2021

Glutamate-induced intracellular calcium changes and neurotoxicity in cortical neurons in vitro: effect of chemical ischemia

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https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Mitochondria and neuronal survival

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https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Mitochondria and Na+/Ca2+ exchange buffer glutamate-induced calcium loads in cultured cortical neurons

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https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Sequestration of glutamate-induced Ca2+ loads by mitochondria in cultured rat hippocampal neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Dominant role of mitochondria in protection against a delayed neuronal Ca2+ overload induced by endogenous excitatory amino acids following a glutamate pulse.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Mitochondrial control of acute glutamate excitotoxicity in cultured cerebellar granule cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Mitochondria accumulate Ca2+ following intense glutamate stimulation of cultured rat forebrain neurones.

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https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Oxidative stress, mitochondrial function, and acute glutamate excitotoxicity in cultured cerebellar granule cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

The regulation of extramitochondrial free calcium ion concentration by rat liver mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

The permeability transition pore as a mitochondrial calcium release channel: a critical appraisal

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https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

The mitochondrial permeability transition.

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https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Role of mitochondrial Ca2+ regulation in neuronal and glial cell signalling

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https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

The lack of extracellular Na+ exacerbates Ca2+-dependent damage of cultured cerebellar granule cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Glutamate-induced mitochondrial depolarisation and perturbation of calcium homeostasis in cultured rat hippocampal neurones

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Inter-Relationships between Proton Electrochemical Gradient, Adenine-Nucleotide Phosphorylation Potential and Respiration, during Substrate-Level and Oxidative Phosphorylation by Mitochondria from Brown Adipose Tissue of Cold-Adapted Guinea-Pigs

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Role of uncoupled and non-coupled oxidations in maintenance of safely low levels of oxygen and its one-electron reductants

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Dependence of H2O2 formation by rat heart mitochondria on substrate availability and donor age.

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https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

A role for uncoupling protein-2 as a regulator of mitochondrial hydrogen peroxide generation

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https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Isolated cerebral and cerebellar mitochondria produce free radicals when exposed to elevated CA2+ and Na+: implications for neurodegeneration

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https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Ca(2+)-induced mitochondrial membrane permeabilization: role of coenzyme Q redox state.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Mitochondrial production of reactive oxygen species in cortical neurons following exposure to N-methyl-D-aspartate

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation

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https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Superoxide production in rat hippocampal neurons: selective imaging with hydroethidine

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https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

In vitro ischemia promotes glutamate-mediated free radical generation and intracellular calcium accumulation in hippocampal pyramidal neurons.

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https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

NMDA-induced superoxide production and neurotoxicity in cultured rat hippocampal neurons: role of mitochondria.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Sources of reactive oxygen species production in excitotoxin- stimulated cerebellar granule cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Glutamate-induced neuron death requires mitochondrial calcium uptake

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Chloromethyltetramethylrosamine (Mitotracker Orange) induces the mitochondrial permeability transition and inhibits respiratory complex I. Implications for the mechanism of cytochrome c release.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Is chloromethyl-X-rosamine useful in measuring mitochondrial transmembrane potential?

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Chloromethyl-X-Rosamine is an aldehyde-fixable potential-sensitive fluorochrome for the detection of early apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Analysis of mitochondrial morphology and function with novel fixable fluorescent stains

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Influx and efflux kinetics of cationic dye binding to respiring mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Rhodamine 123 as a probe of transmembrane potential in isolated rat-liver mitochondria: spectral and metabolic properties

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Monitoring of relative mitochondrial membrane potential in living cells by fluorescence microscopy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Bcl-xL regulates apoptosis by heterodimerization-dependent and -independent mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Excitotoxic degeneration is initiated at non-random sites in cultured rat cerebellar neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Relative mitochondrial membrane potential and [Ca2+]i in type I cells isolated from the rabbit carotid body

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Ca(2+)-dependent changes in the mitochondrial energetics in single dissociated mouse sensory neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Measurement of mitochondrial membrane potential using fluorescent rhodamine derivatives

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https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Simultaneous imaging of cell and mitochondrial membrane potentials

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https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Imaging in five dimensions: time-dependent membrane potentials in individual mitochondria

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https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Mitochondrial depolarization accompanies cytochrome c release during apoptosis in PC6 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Membrane potential can be determined in individual cells from the nernstian distribution of cationic dyes

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Physiological cytosolic Ca2+ transients evoke concurrent mitochondrial depolarizations.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Inhibitors of NADH-ubiquinone reductase: an overview

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Quantitative assay by flow cytometry of the mitochondrial membrane potential in intact cells

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Mitochondrial dysfunction in lymphocytes from old mice: enhanced activation of the permeability transition

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https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

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https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

The overexpression of Bax produces cell death upon induction of the mitochondrial permeability transition

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

J-aggregate formation of a carbocyanine as a quantitative fluorescent indicator of membrane potential

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Mitochondrial membrane potential monitored by JC-1 dye.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Mitochondrial membrane potential in single living adult rat cardiac myocytes exposed to anoxia or metabolic inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

A new method for the cytofluorimetric analysis of mitochondrial membrane potential using the J-aggregate forming lipophilic cation 5,5',6,6'-tetrachloro-1,1',3,3'-tetraethylbenzimidazolcarbocyanine iodide (JC-1).

1 reference

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7 January 2021

Functional Heterogeneity of an Isolated Mitochondrial Population Revealed by Cytofluorometric Analysis at the Single Organelle Level

1 reference

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7 January 2021

JC-1, but not DiOC6(3) or rhodamine 123, is a reliable fluorescent probe to assess delta psi changes in intact cells: implications for studies on mitochondrial functionality during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Intracellular fluorescent probe concentrations by confocal microscopy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Mitochondrial perturbations define lymphocytes undergoing apoptotic depletion in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo.

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https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Generation of hydrogen peroxide precedes loss of mitochondrial membrane potential during DNA alkylation-induced apoptosis

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https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Modulation of neuronal mitochondrial membrane potential by the NMDA receptor: role of arachidonic acid.

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7 January 2021

Flow cytometric study of mitochondrial dysfunction after AMPA receptor activation

1 reference

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7 January 2021

Changes in membrane potential during calcium ion influx and efflux across the mitochondrial membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Localization of mitochondria in living cells with rhodamine 123

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Calcineurin and mitochondrial function in glutamate-induced neuronal cell death.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Trifluoperazine and dibucaine-induced inhibition of glutamate-induced mitochondrial depolarization in rat cultured forebrain neurones

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Glutathione depletion and neuronal cell death: the role of reactive oxygen intermediates and mitochondrial function.

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https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Energy transduction in intact synaptosomes. Influence of plasma-membrane depolarization on the respiration and membrane potential of internal mitochondria determined in situ

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Rapid uncoupling of oxidative phosphorylation accompanies glutamate toxicity in rat cerebellar granule cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Oxidative modification of a carboxyl-terminal vicinal methionine in calmodulin by hydrogen peroxide inhibits calmodulin-dependent activation of the plasma membrane Ca-ATPase

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https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

Loss of conformational stability in calmodulin upon methionine oxidation

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https://api.crossref.org/works/10.1016%2FS0166-2236%2899%2901534-9

7 January 2021

10.1016/S0166-2236(99)01534-9

Identifiers

DOI

1 reference

29 July 2017

1 reference

PubMed ID

10717676