Ligand-mediated tertiary structure changes of reconstituted P-glycoprotein. A tryptophan fluorescence quenching analysis (Q33864499)

29 July 2017

Ligand-mediated tertiary structure changes of reconstituted P-glycoprotein. A tryptophan fluorescence quenching analysis (English)

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29 July 2017

N Sonveaux

1

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29 July 2017

C Vigano

2

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29 July 2017

A B Shapiro

3

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29 July 2017

V Ling

4

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29 July 2017

J M Ruysschaert

5

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29 July 2017

language of work or name

English

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publication date

1 June 1999

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Journal of Biological Chemistry

29 July 2017

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29 July 2017

274

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29 July 2017

25

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29 July 2017

17649-17654

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MDR1 gene expression in solid tumours

29 July 2017

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https://api.crossref.org/works/10.1074%2FJBC.274.25.17649

Membrane topology of a cysteine-less mutant of human P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17649

Transmembrane organization of mouse P-glycoprotein determined by epitope insertion and immunofluorescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17649

Topological folding and proteolysis profile of P-glycoprotein in membranes of multidrug-resistant cells: implications for the drug-transport mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17649

ATP-dependent transport systems in bacteria and humans: relevance to cystic fibrosis and multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17649

ATP-dependent transport of vinblastine in vesicles from human multidrug-resistant cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17649

The biochemistry of P-glycoprotein-mediated multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17649

Covalent modification of human P-glycoprotein mutants containing a single cysteine in either nucleotide-binding fold abolishes drug-stimulated ATPase activity

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.25.17649

The catalytic cycle of P-glycoprotein

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.25.17649

P-glycoprotein is stably inhibited by vanadate-induced trapping of nucleotide at a single catalytic site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17649

P-glycoprotein--a mediator of multidrug resistance in tumour cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17649

Mechanism of action of human P-glycoprotein ATPase activity. Photochemical cleavage during a catalytic transition state using orthovanadate reveals cross-talk between the two ATP sites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17649

Site-directed fluorescence labeling of P-glycoprotein on cysteine residues in the nucleotide binding domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17649

Cellular uptake, cytotoxicity, and transport kinetics of anthracyclines in human sensitive and multidrug-resistant K562 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17649

A simplification of the protein assay method of Lowry et al. which is more generally applicable

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17649

Reconstitution of drug transport by purified P-glycoprotein

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.25.17649

P-glycoprotein-mediated Hoechst 33342 transport out of the lipid bilayer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17649

Photoaffinity labeling of the multidrug-resistance-related P-glycoprotein with photoactive analogs of verapamil

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17649

Conformational changes of P-glycoprotein by nucleotide binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17649

Dissection of drug-binding-induced conformational changes in P-glycoprotein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17649

P-glycoprotein function involves conformational transitions detectable by differential immunoreactivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17649

The P-glycoprotein efflux pump: how does it transport drugs?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17649

Evidence for two nonidentical drug-interaction sites in the human P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17649

Positively cooperative sites for drug transport by P-glycoprotein with distinct drug specificities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17649

Transmembrane aromatic amino acid distribution in P-glycoprotein. A functional role in broad substrate specificity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17649

21 January 2018

Identifiers

DOI

10.1074/JBC.274.25.17649

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29 July 2017

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