Pathways of T cell pathology in models of chronic intestinal inflammation (Q33867150)

29 July 2017

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title

Pathways of T cell pathology in models of chronic intestinal inflammation (English)

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29 July 2017

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Simpson SJ

1

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29 July 2017

de Jong YP

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2

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29 July 2017

Comiskey M

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3

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29 July 2017

Terhorst C

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4

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29 July 2017

1 January 2000

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International Reviews of Immunology

29 July 2017

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29 July 2017

19

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29 July 2017

1-37

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29 July 2017

1

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On the etiology of Crohn disease

29 July 2017

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Clarifying the causes of Crohn's

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Inflammatory bowel disease (1)

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

The germfree state prevents development of gut and joint inflammatory disease in HLA-B27 transgenic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Spontaneous inflammatory disease in transgenic rats expressing HLA-B27 and human beta 2m: an animal model of HLA-B27-associated human disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Early-onset multifocal inflammation in the transforming growth factor beta 1-null mouse is lymphocyte mediated

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Interleukin-10-deficient mice develop chronic enterocolitis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Impaired defense of intestinal mucosa in mice lacking intestinal trefoil factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Ulcerative colitis and adenocarcinoma of the colon in G alpha i2-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

A block in both early T lymphocyte and natural killer cell development in transgenic mice with high-copy numbers of the human CD3E gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Development and function of T lymphocytes and natural killer cells after bone marrow transplantation of severely immunodeficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Developmental control point in induction of thymic cortex regulated by a subpopulation of prothymocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Over-expression of CD3 epsilon transgenes blocks T lymphocyte development.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

CD4+ T cells that express high levels of CD45RB induce wasting disease when transferred into congenic severe combined immunodeficient mice. Disease development is prevented by cotransfer of purified CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Regulatory interactions between CD45RBhigh and CD45RBlow CD4+ T cells are important for the balance between protective and pathogenic cell-mediated immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Inhibition of Th1 responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

A monoclonal antibody to murine CD45R distinguishes CD4 T cell populations that produce different cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Functional diversity of helper T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Acquisition of lymphokine-producing phenotype by CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Expression of pro-inflammatory cytokines by TCR alpha beta+ and TCR gamma delta+ T cells in an experimental model of colitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Cellular responses to interferon-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Selective suppression of interleukin-12 induction after macrophage receptor ligation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Interleukin-12 is produced by dendritic cells and mediates T helper 1 development as well as interferon-gamma production by T helper 1 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Interleukin-12 primes human CD4 and CD8 T cell clones for high production of both interferon-gamma and interleukin-10.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Interleukin-12 regulates the proliferation of Th1, but not Th2 or Th0, clones.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

IFN-gamma induces IL-12 mRNA expression by a murine macrophage cell line, J774.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

STATs: signal transducers and activators of transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Stat3 and Stat4: members of the family of signal transducers and activators of transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Stat4, a novel gamma interferon activation site-binding protein expressed in early myeloid differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Interleukin 12, interferon gamma, and tumor necrosis factor alpha are the key cytokines of the generalized Shwartzman reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Antibodies to interleukin 12 abrogate established experimental colitis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Prevention of experimental autoimmune encephalomyelitis by antibodies against interleukin 12.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Effect of anti-interferon-gamma and anti-interleukin-2 monoclonal antibody treatment on the development of actively and passively induced experimental allergic encephalomyelitis in the SJL/J mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Myelin basic protein-specific T helper 2 (Th2) cells cause experimental autoimmune encephalomyelitis in immunodeficient hosts rather than protect them from the disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

T helper 2 (Th2) T cells induce acute pancreatitis and diabetes in immune-compromised nonobese diabetic (NOD) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Cytokine imbalance and autoantibody production in T cell receptor-alpha mutant mice with inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Cloning of a new cytokine that induces IFN-gamma production by T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Interferon-gamma-inducing factor enhances T helper 1 cytokine production by stimulated human T cells: synergism with interleukin-12 for interferon-gamma production

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

IGIF does not drive Th1 development but synergizes with IL-12 for interferon-gamma production and activates IRAK and NFkappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Taming TNF: strategies to restrain this proinflammatory cytokine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Treatment of Crohn's disease with anti-tumor necrosis factor chimeric monoclonal antibody (cA2).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Mechanism of interleukin 12-mediated toxicities during experimental viral infections: role of tumor necrosis factor and glucocorticoids

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Surface lymphotoxin alpha/beta complex is required for the development of peripheral lymphoid organs

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Distinct roles in lymphoid organogenesis for lymphotoxins alpha and beta revealed in lymphotoxin beta-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Signaling through the lymphotoxin beta receptor induces the death of some adenocarcinoma tumor lines

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Massive upregulation of the Fas ligand in lpr and gld mice: implications for Fas regulation and the graft-versus-host disease-like wasting syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Cytotoxic reactivity of gut lamina propria CD4+ alpha beta T cells in SCID mice with colitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Evidence that CD4+, but not CD8+ T cells are responsible for murine interleukin-2-deficient colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Attenuation of colitis in the cotton-top tamarin by anti-alpha 4 integrin monoclonal antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Multiple pathways for the initiation of T helper 2 (Th2) responses

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

T cells in inflammatory bowel disease: protective and pathogenic roles.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Chronic intestinal inflammation: an unexpected outcome in cytokine or T cell receptor mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Oral tolerance: immune mechanisms and treatment of autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

The thymus contains a high frequency of cells that prevent autoimmune diabetes on transfer into prediabetic recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

The physiological role of regulatory T cells in the prevention of autoimmunity: the function of the thymus in the generation of the regulatory T cell subset

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

T cell-mediated pathology in two models of experimental colitis depends predominantly on the interleukin 12/Signal transducer and activator of transcription (Stat)-4 pathway, but is not conditional on interferon gamma expression by T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Both the lymphotoxin and tumor necrosis factor pathways are involved in experimental murine models of colitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Critical role for β7 integrins in formation of the gut-associated lymphoid tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

Differential production of interferon-γ and interleukin-4 in response to Th1- and Th2-stimulating pathogens by γδ T cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180009048387

10.3109/08830180009048387

21 January 2018

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DOI

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29 July 2017

1 reference