Efficient synthetic inhibitors of anthrax lethal factor (Q33868811)

29 July 2017

Efficient synthetic inhibitors of anthrax lethal factor (English)

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29 July 2017

Barbara Becattini

8

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Martino Forino

object named as

Martino Forino

1

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Roberto Fattorusso

object named as

Roberto Fattorusso

7

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Alex Strongin

object named as

Alex Y Strongin

15

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author name string

Sherida Johnson

2

1 reference

29 July 2017

Thiang Y Wong

3

1 reference

29 July 2017

Dmitri V Rozanov

4

1 reference

29 July 2017

Alexei Y Savinov

5

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29 July 2017

Wei Li

6

1 reference

29 July 2017

Andrew J Orry

9

1 reference

29 July 2017

Dawoon Jung

10

1 reference

29 July 2017

Ruben A Abagyan

11

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29 July 2017

Jeffrey W Smith

12

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29 July 2017

Ken Alibek

13

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29 July 2017

Robert C Liddington

14

1 reference

29 July 2017

Maurizio Pellecchia

16

1 reference

29 July 2017

language of work or name

English

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publication date

27 June 2005

1 reference

Proceedings of the National Academy of Sciences of the United States of America

29 July 2017

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29 July 2017

102

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29 July 2017

9499-9504

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29 July 2017

27

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NMR-based techniques in the hit identification and optimisation processes

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1160517

Targeting apoptosis via chemical design: inhibition of bid-induced cell death by small organic molecules.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1160517

The application of x-ray, NMR, and molecular modeling in the design of MMP inhibitors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1160517

The design and synthesis of aryl hydroxamic acid inhibitors of MMPs and TACE.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1160517

Chemical screening by mass spectrometry to identify inhibitors of anthrax lethal factor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1160517

Identification of small molecule inhibitors of anthrax lethal factor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1160517

The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1160517

Observations on experimental anthrax; demonstration of a specific lethal factor produced in vivo by Bacillus anthracis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1160517

Human capillary morphogenesis protein 2 functions as an anthrax toxin receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1160517

Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1160517

28 July 2018

NMR in drug discovery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1160517

A Common Mechanism Underlying Promiscuous Inhibitors from Virtual and High-Throughput Screening

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1160517

Crystal structure of the anthrax lethal factor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1160517

Identification of the cellular receptor for anthrax toxin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1160517

Spin label enhanced NMR screening

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1160517

Susceptibility of mitogen-activated protein kinase kinase family members to proteolysis by anthrax lethal factor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1160517

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1160517

Anthrax lethal factor cleaves the N-terminus of MAPKKs and induces tyrosine/threonine phosphorylation of MAPKs in cultured macrophages

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1160517

Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1160517

Anthrax pathogenesis and host response.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1160517

Crystal structure of the anthrax toxin protective antigen

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1160517

The properties of known drugs. 1. Molecular frameworks

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1160517

On the role of macrophages in anthrax

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1160517

Anthrax toxin edema factor: a bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1160517

Anthrax lethal factor cleaves MKK3 in macrophages and inhibits the LPS/IFNgamma-induced release of NO and TNFalpha

28 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502733102

NMR spectroscopy techniques for screening and identifying ligand binding to protein receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502733102

Substrate hydrolysis by matrix metalloproteinase-9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502733102

Dominant-Negative Mutants of a Toxin Subunit: An Approach to Therapy of Anthrax

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502733102

NMR-based structural characterization of large protein-ligand interactions

21 January 2018

1 reference

12 December 2020

A general NMR method for rapid, efficient, and reliable biochemical screening

1 reference

12 December 2020

A novel coumarin-labelled peptide for sensitive continuous assays of the matrix metalloproteinases

1 reference

12 December 2020

Characterization of Ligand Binding by Saturation Transfer Difference NMR Spectroscopy

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0502733102

1 reference

release_yfz24nhcjrhv7ohuhtkgnffrmm

29 July 2017

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1 reference

Fatcat

https://api.fatcat.wiki/v0/release/yfz24nhcjrhv7ohuhtkgnffrmm

24 November 2022

mapped directly with Wikidata item

PMCID

1160517

1 reference

29 July 2017

1 reference