Small molecule-driven mitophagy-mediated NLRP3 inflammasome inhibition is responsible for the prevention of colitis-associated cancer (Q33878967)

29 July 2017

Small molecule-driven mitophagy-mediated NLRP3 inflammasome inhibition is responsible for the prevention of colitis-associated cancer (English)

1 reference

29 July 2017

1 reference

Wenjie Guo

1

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29 July 2017

Yang Sun

2

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29 July 2017

Wen Liu

3

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29 July 2017

Xingxin Wu

4

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29 July 2017

Lele Guo

5

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29 July 2017

Peifen Cai

6

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29 July 2017

Xuefeng Wu

7

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29 July 2017

Xudong Wu

8

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29 July 2017

Yan Shen

9

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29 July 2017

Yongqian Shu

10

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29 July 2017

Yanhong Gu

11

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29 July 2017

Qiang Xu

12

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29 July 2017

1 June 2014

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29 July 2017

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29 July 2017

10

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29 July 2017

972-985

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29 July 2017

6

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Inflammasome in intestinal inflammation and cancer

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091180

Novel monofunctional platinum (II) complex Mono-Pt induces apoptosis-independent autophagic cell death in human ovarian carcinoma cells, distinct from cisplatin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091180

Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091180

Inflammatory bowel disease cancer risk, detection and surveillance

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091180

Mitophagy: mechanisms, pathophysiological roles, and analysis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091180

IL-1β mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4(+) Th17 cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091180

Genetic and epigenetic events generate multiple pathways in colorectal cancer progression

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091180

Andrographolide sensitizes cisplatin-induced apoptosis via suppression of autophagosome-lysosome fusion in human cancer cells.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091180

The cytokine release inhibitory drug CRID3 targets ASC oligomerisation in the NLRP3 and AIM2 inflammasomes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091180

The inflammasome: an integrated view

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091180

28 July 2018

Global cancer statistics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091180

Andrographolide enhances nuclear factor-kappaB subunit p65 Ser536 dephosphorylation through activation of protein phosphatase 2A in vascular smooth muscle cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091180

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091180

A role for mitochondria in NLRP3 inflammasome activation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091180

The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091180

Nonresolving inflammation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091180

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091180

IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091180

Cytokines: from gut inflammation to colorectal cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091180

Chemically induced mouse models of intestinal inflammation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091180

A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091180

Antiviral properties of ent-labdene diterpenes of Andrographis paniculata nees, inhibitors of herpes simplex virus type 1.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091180

Annual report to the nation on the status of cancer, 1975-2000, featuring the uses of surveillance data for cancer prevention and control

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091180

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091180

Interleukin 18 is a primary mediator of the inflammation associated with dextran sulphate sodium induced colitis: blocking interleukin 18 attenuates intestinal damage

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091180

Neutralization of interleukin-18 reduces severity in murine colitis and intestinal IFN-gamma and TNF-alpha production

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091180

NF-kappaB signaling proteins as therapeutic targets for inflammatory bowel diseases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091180

Involvement of interleukin-1 in the development of ulcerative colitis induced by dextran sulfate sodium in mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091180

Expression of interleukin 1 beta and interleukin 1 beta converting enzyme by intestinal macrophages in health and inflammatory bowel disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091180

Biologic basis for interleukin-1 in disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091180

Role of interleukin 1 in inflammatory bowel disease--enhanced production during active disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091180

Interleukin 1 in ulcerative colitis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091180

Evaluation of an interleukin-1 receptor antagonist in the rat acetic acid-induced colitis model

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091180

Inflammation and colorectal cancer: colitis-associated neoplasia

28 July 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.28374

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.28374

Hallmarks of Cancer: The Next Generation

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.28374

Inflammation and colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.28374

In vitro and in vivo anti-inflammatory effects of andrographolide

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.28374

Neuroprotective effects of andrographolide in a rat model of permanent cerebral ischaemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.28374

Andrographolide, a potential cancer therapeutic agent isolated from Andrographis paniculata

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.28374

Prostaglandins and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.28374

Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.28374

The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.28374

IL-1 beta -converting enzyme (caspase-1) in intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.28374

The interleukin-1 beta-converting enzyme inhibitor pralnacasan reduces dextran sulfate sodium-induced murine colitis and T helper 1 T-cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.28374

Andrographolide induces autophagic cell death in human liver cancer cells through cyclophilin D-mediated mitochondrial permeability transition pore.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.28374

Inducible NOS-induced chloride intracellular channel 4 (CLIC4) nuclear translocation regulates macrophage deactivation.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.28374

Colorectal cancer and inflammatory bowel disease: epidemiology, risk factors, mechanisms of carcinogenesis and prevention strategies

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091180

Dangerous Liaisons: Mitochondrial DNA Meets the NLRP3 Inflammasome

29 October 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.28374

Protective and aggravating effects of Nlrp3 inflammasome activation in IBD models: influence of genetic and environmental factors

21 January 2018

1 reference

12 December 2020

The ICE inhibitor pralnacasan prevents DSS-induced colitis in C57BL/6 mice and suppresses IP-10 mRNA but not TNF-alpha mRNA expression

1 reference

12 December 2020

Molecular genetics of colorectal cancer

1 reference

12 December 2020

Andrographolide acts as an anti-inflammatory agent in LPS-stimulated RAW264.7 macrophages by inhibiting STAT3-mediated suppression of the NF-κB pathway

1 reference

12 December 2020

Enhanced secretion of tumour necrosis factor-alpha, IL-6, and IL-1 beta by isolated lamina propria mononuclear cells from patients with ulcerative colitis and Crohn's disease

1 reference

12 December 2020

Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome

1 reference

12 December 2020

Cancer risk in patients with inflammatory bowel disease: a population-based study

1 reference

12 December 2020

Mitochondrial control of the NLRP3 inflammasome

1 reference

12 December 2020

1 reference

12 December 2020

Identifiers

DOI

10.4161/AUTO.28374

1 reference

release_xg2jmwgykzgsrcxpj3agep5cvy

29 July 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/xg2jmwgykzgsrcxpj3agep5cvy

24 November 2022

mapped directly with Wikidata item

PMCID

4091180

1 reference

29 July 2017

1 reference