A highly toxic cellular prion protein induces a novel, nonapoptotic form of neuronal death (Q33882410)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20472884%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

title

A highly toxic cellular prion protein induces a novel, nonapoptotic form of neuronal death (English)

1 reference

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2 February 2020

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7

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2 February 2020

David A Harris

8

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2 February 2020

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6

John W Olney

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2 February 2020

author name string

Heather M Christensen

1

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2 February 2020

Krikor Dikranian

2

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2 February 2020

Aimin Li

3

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2 February 2020

Kathleen C Baysac

4

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2 February 2020

Ken C Walls

5

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2 February 2020

language of work or name

English

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publication date

14 May 2010

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The American Journal of Pathology

2 February 2020

published in

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2 February 2020

volume

176

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2 February 2020

issue

6

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2 February 2020

page(s)

2695-2706

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A deleted prion protein that is neurotoxic in vivo is localized normally in cultured cells

2 February 2020

cites work

1 reference

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5 July 2018

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Stress-protective signalling of prion protein is corrupted by scrapie prions

5 July 2018

1 reference

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Prion protein attenuates excitotoxicity by inhibiting NMDA receptors

5 July 2018

1 reference

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Mild traumatic brain injury to the infant mouse causes robust white matter axonal degeneration which precedes apoptotic death of cortical and thalamic neurons.

5 July 2018

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Diminishing apoptosis by deletion of Bax or overexpression of Bcl-2 does not protect against infectious prion toxicity in vivo

5 July 2018

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Doppel induces degeneration of cerebellar Purkinje cells independently of Bax

5 July 2018

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Lethal recessive myelin toxicity of prion protein lacking its central domain

5 July 2018

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Cell death in the nervous system

5 July 2018

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A systematic review of prion therapeutics in experimental models

5 July 2018

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Anchorless prion protein results in infectious amyloid disease without clinical scrapie

5 July 2018

1 reference

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Cellular prion protein neuroprotective function: implications in prion diseases

5 July 2018

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Mitochondrial mechanisms of neural cell apoptosis

5 July 2018

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Poly(ADP-ribose) polymerase-1 and apoptosis inducing factor in neurotoxicity

5 July 2018

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Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis.

5 July 2018

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Live and let die: regulatory mechanisms in Fas-mediated apoptosis.

5 July 2018

1 reference

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Morphological and biochemical aspects of apoptosis, oncosis and necrosis

5 July 2018

1 reference

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Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor

5 July 2018

1 reference

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Poly(ADP-ribose) polymerase-1 cleavage during apoptosis: an update

5 July 2018

1 reference

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Doppel-induced cerebellar degeneration in transgenic mice

5 July 2018

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Apoptosis in the in vivo mammalian forebrain

5 July 2018

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Onset of ataxia and Purkinje cell loss in PrP null mice inversely correlated with Dpl level in brain

5 July 2018

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

5 July 2018

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The biochemistry of apoptosis

5 July 2018

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5 July 2018

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Bax inactivation in lurcher mutants rescues cerebellar granule cells but not purkinje cells or inferior olivary neurons

5 July 2018

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5 July 2018

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5 July 2018

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Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

5 July 2018

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BCL-2 counteracts Doppel-induced apoptosis of prion-protein-deficient Purkinje cells in the Ngsk Prnp(0/0) mouse.

5 July 2018

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Bcl-2 overexpression delays caspase-3 activation and rescues cerebellar degeneration in prion-deficient mice that overexpress amino-terminally truncated prion

29 October 2018

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BAX contributes to Doppel-induced apoptosis of prion-protein-deficient Purkinje cells

29 October 2018

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N-terminally deleted forms of the prion protein activate both Bax-dependent and Bax-independent neurotoxic pathways.

29 October 2018

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Neonatal lethality in transgenic mice expressing prion protein with a deletion of residues 105-125.

29 October 2018

1 reference

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Bax deletion does not protect neurons from BSE-induced death

29 October 2018

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Caspase-3 deficiency during development increases vulnerability to hypoxic-ischemic injury through caspase-3-independent pathways

29 October 2018

1 reference

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Role of caspase-3 in ethanol-induced developmental neurodegeneration

29 October 2018

1 reference

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Light and electron microscopic assessment of progressive atrophy following moderate traumatic brain injury in the rat.

29 October 2018

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Ethanol-induced neuroapoptosis in the developing rodent cerebellum and related brain stem structures

29 October 2018

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The influence of age on apoptotic and other mechanisms of cell death after cerebral hypoxia-ischemia.

29 October 2018

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Neurons exclusively express N-Bak, a BH3 domain-only Bak isoform that promotes neuronal apoptosis

29 October 2018

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An autoradiographic analysis of histogenesis in the mouse cerebellum

29 October 2018

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High molecular weight DNA fragments are processed by caspase sensitive or caspase independent pathways in cultures of cerebellar granule neurons

29 October 2018

1 reference

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Role of caspase-3 activation in cerebral ischemia-induced neurodegeneration in adult and neonatal brain

29 October 2018

1 reference

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Distinguishing excitotoxic from apoptotic neurodegeneration in the developing rat brain

29 October 2018

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Neurological illness in transgenic mice expressing a prion protein with an insertional mutation.

29 October 2018

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Normal host prion protein necessary for scrapie-induced neurotoxicity

29 October 2018

1 reference

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Truncated Prion Protein and Doppel Are Myelinotoxic in the Absence of Oligodendrocytic PrPC

29 October 2018

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NMDA and kainate induce internucleosomal DNA cleavage associated with both apoptotic and necrotic cell death in the neonatal rat brain

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20472884

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.2353/AJPATH.2010.091007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20472884%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20472884%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

PubMed publication ID

20472884

1 reference