TMPRSS2, a serine protease expressed in the prostate on the apical surface of luminal epithelial cells and released into semen in prostasomes, is misregulated in prostate cancer cells (Q33882562)

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English	TMPRSS2, a serine protease expressed in the prostate on the apical surface of luminal epithelial cells and released into semen in prostasomes, is misregulated in prostate cancer cells	scientific article

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scholarly article

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30 January 2020

TMPRSS2, a serine protease expressed in the prostate on the apical surface of luminal epithelial cells and released into semen in prostasomes, is misregulated in prostate cancer cells (English)

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30 January 2020

prostate cancer

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based on heuristic

inferred from title

2

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30 January 2020

3

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30 January 2020

author name string

Ya-Wen Chen

1

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30 January 2020

Amanda Lucht

4

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30 January 2020

Feng-Pai Chou

5

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30 January 2020

Wei Huang

6

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30 January 2020

Thomas C Havighurst

7

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30 January 2020

KyungMann Kim

8

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30 January 2020

Jehng-Kang Wang

9

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30 January 2020

Toni M Antalis

10

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30 January 2020

Michael D Johnson

11

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30 January 2020

Chen-Yong Lin

12

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30 January 2020

language of work or name

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publication date

9 April 2010

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30 January 2020

The American Journal of Pathology

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30 January 2020

176

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30 January 2020

6

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30 January 2020

2986-2996

1 reference

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30 January 2020

Quantitative expression of TMPRSS2 transcript in prostate tumor cells reflects TMPRSS2-ERG fusion status.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877858

5 July 2018

Identification of PDE4D as a proliferation promoting factor in prostate cancer using a Sleeping Beauty transposon-based somatic mutagenesis screen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877858

5 July 2018

Purification from human milk of matriptase complexes with secreted serpins: mechanism for inhibition of matriptase other than HAI-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877858

5 July 2018

Role of the TMPRSS2-ERG gene fusion in prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877858

5 July 2018

Phenotypic analysis of mice lacking the Tmprss2-encoded protease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877858

5 July 2018

Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877858

5 July 2018

The membrane-anchored serine protease, TMPRSS2, activates PAR-2 in prostate cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877858

5 July 2018

Type II transmembrane serine proteases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877858

5 July 2018

Membrane anchored serine proteases: a rapidly expanding group of cell surface proteolytic enzymes with potential roles in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877858

5 July 2018

The Activation of Matriptase Requires Its Noncatalytic Domains, Serine Protease Domain, and Its Cognate Inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877858

5 July 2018

Regulation of the epithelial sodium channel by serine proteases in human airways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877858

5 July 2018

Cloning and characterization of the cDNA and gene for human epitheliasin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877858

5 July 2018

Catalytic cleavage of the androgen-regulated TMPRSS2 protease results in its secretion by prostate and prostate cancer epithelia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877858

5 July 2018

Expression of transmembrane serine protease TMPRSS2 in mouse and human tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877858

5 July 2018

Type II transmembrane serine proteases. Insights into an emerging class of cell surface proteolytic enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877858

5 July 2018

Prostate-localized and androgen-regulated expression of the membrane-bound serine protease TMPRSS2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877858

5 July 2018

Purification and characterization of a complex containing matriptase and a Kunitz-type serine protease inhibitor from human milk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877858

5 July 2018

Monoclonal antibodies against human prostasomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877858

5 July 2018

Cloning of the TMPRSS2 gene, which encodes a novel serine protease with transmembrane, LDLRA, and SRCR domains and maps to 21q22.3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877858

5 July 2018

Fusion of sperm with prostasomes: effects on membrane fluidity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877858

5 July 2018

Motility stimulant effects of prostasome inclusion in swim-up medium on cryopreserved human spermatozoa.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877858

5 July 2018

Fusion of human sperm to prostasomes at acidic pH.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877858

5 July 2018

Promotive effect on human sperm progressive motility by prostasomes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877858

5 July 2018

Association of TMPRSS2 and KLK11 gene expression levels with clinical progression of human prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877858

29 October 2018

Protein expression of matriptase and its cognate inhibitor HAI-1 in human prostate cancer: a tissue microarray and automated quantitative analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877858

29 October 2018

The androgen-regulated type II serine protease TMPRSS2 is differentially expressed and mislocalized in prostate adenocarcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877858

29 October 2018

TMPRSS2:ERG fusion by translocation or interstitial deletion is highly relevant in androgen-dependent prostate cancer, but is bypassed in late-stage androgen receptor-negative prostate cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877858

29 October 2018

Matriptase activation and shedding with HAI-1 is induced by steroid sex hormones in human prostate cancer cells, but not in breast cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877858

29 October 2018

Endothelial cell serine proteases expressed during vascular morphogenesis and angiogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877858

29 October 2018

The TMPRSS2 gene encoding transmembrane serine protease is overexpressed in a majority of prostate cancer patients: detection of mutated TMPRSS2 form in a case of aggressive disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877858

29 October 2018

Prostasome-like particles in stallion semen.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877858

29 October 2018

Characteristics of human prostasomes isolated from three different sources

1 reference

https://pubmed.ncbi.nlm.nih.gov/20382709

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced recruitment of motile spermatozoa by prostasome inclusion in swim-up medium

1 reference

https://pubmed.ncbi.nlm.nih.gov/20382709

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Promotive effect by prostasomes on normal human spermatozoa exhibiting no forward motility due to buffer washings

1 reference

https://pubmed.ncbi.nlm.nih.gov/20382709

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolongation and improvement of prostasome promotive effect on sperm forward motility

1 reference

https://pubmed.ncbi.nlm.nih.gov/20382709

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human seminal plasma prevents sperm from becoming acrosomally responsive to the agonist, progesterone: cholesterol is the major inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/20382709

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of a novel, membrane-bound, 80-kDa matrix-degrading protease from human breast cancer cells. Monoclonal antibody production, isolation, and localization

1 reference

https://pubmed.ncbi.nlm.nih.gov/20382709

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prostasome fraction of human seminal plasma prevents sperm from becoming acrosomally responsive to the agonist progesterone

1 reference

https://pubmed.ncbi.nlm.nih.gov/20382709

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty acid pattern of human prostasome lipid

1 reference

https://pubmed.ncbi.nlm.nih.gov/20382709

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The motility of human spermatozoa as influenced by prostasomes at various pH levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/20382709

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Type II transmembrane serine proteases

1 reference

https://pubmed.ncbi.nlm.nih.gov/20382709

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2353/AJPATH.2010.090665

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20382709%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20382709%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20382709%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

ResearchGate publication ID

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