Tocilizumab, a proposed therapy for the cachexia of Interleukin6-expressing lung cancer (Q33882832)

29 July 2017

Tocilizumab, a proposed therapy for the cachexia of Interleukin6-expressing lung cancer (English)

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29 July 2017

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Katsutoshi Ando

1

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29 July 2017

Fumiyuki Takahashi

2

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29 July 2017

Motoyasu Kato

3

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29 July 2017

Norihiro Kaneko

4

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29 July 2017

Tokuhide Doi

5

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29 July 2017

Yuichiro Ohe

6

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29 July 2017

Fumiaki Koizumi

7

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29 July 2017

Kazuto Nishio

8

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29 July 2017

Kazuhisa Takahashi

9

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29 July 2017

language of work or name

English

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publication date

10 July 2014

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29 July 2017

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29 July 2017

9

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29 July 2017

7

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29 July 2017

e102436

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Creative Commons Attribution 4.0 International

29 July 2017

start time

10 July 2014

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Hochuekkito (TJ-41), a Kampo Formula, Ameliorates Cachexia Induced by Colon 26 Adenocarcinoma in Mice.

5 July 2018

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The relationships between body composition and the systemic inflammatory response in patients with primary operable colorectal cancer.

5 July 2018

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Safety and efficacy of tocilizumab for the treatment of rheumatoid arthritis

5 July 2018

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Definition and classification of cancer cachexia: an international consensus

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092149

Humanized anti-interleukin-6 receptor antibody suppresses tumor angiogenesis and in vivo growth of human oral squamous cell carcinoma.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092149

Mechanisms of cancer cachexia

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092149

Novel models of cancer-related anemia in mice inoculated with IL-6-producing tumor cells

5 July 2018

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Sophocarpine and matrine inhibit the production of TNF-alpha and IL-6 in murine macrophages and prevent cachexia-related symptoms induced by colon26 adenocarcinoma in mice

5 July 2018

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Interleukin-6 and its receptor in cancer: implications for translational therapeutics

5 July 2018

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Altered recognition of antigen is a mechanism of CD8+ T cell tolerance in cancer

5 July 2018

1 reference

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Suppression of antitumor immunity by IL-10 and TGF-beta-producing T cells infiltrating the growing tumor: influence of tumor environment on the induction of CD4+ and CD8+ regulatory T cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092149

Definition of cancer cachexia: effect of weight loss, reduced food intake, and systemic inflammation on functional status and prognosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092149

Humanized anti-interleukin-6 receptor antibody treatment of multicentric Castleman disease

5 July 2018

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Mechanisms of suppression by suppressor T cells

5 July 2018

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Interleukin-6: from basic science to medicine--40 years in immunology

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092149

Pathogenesis of cancer cachexia.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092149

Appetite and cancer-associated anorexia: a review.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092149

Cachexia in cancer patients

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092149

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092149

Interleukin-6 cDNA transfected Lewis lung carcinoma cells show unaltered net tumour growth rate but cause weight loss and shortened survival in syngeneic mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092149

Prognostic effect of weight loss prior to chemotherapy in cancer patients. Eastern Cooperative Oncology Group

5 July 2018

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Study of the molecular mechanism of decreased liver synthesis of albumin in inflammation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092149

Interleukin 6, the third mediator of acute-phase reaction, modulates hepatic protein synthesis in human and mouse. Comparison with interleukin 1 beta and tumor necrosis factor-alpha

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092149

Methylprednisolone as palliative therapy for female terminal cancer patients. The Methylprednisolone Female Preterminal Cancer Study Group

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092149

Action of oral methylprednisolone in terminal cancer patients: a prospective randomized double-blind study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092149

Increased resting energy expenditure and weight loss are related to a systemic inflammatory response in lung cancer patients

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0102436

Possible role for tocilizumab, an anti-interleukin-6 receptor antibody, in treating cancer cachexia

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0102436

Osteopontin overproduced by tumor cells acts as a potent angiogenic factor contributing to tumor growth.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0102436

A new look at the statistical model identification

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0102436

Cachexia worsens prognosis in patients with resectable pancreatic cancer

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0102436

Serum albumin is an important prognostic factor for carotid blowout syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0102436

The key role of IL-6-arginase cascade for inducing dendritic cell-dependent CD4(+) T cell dysfunction in tumor-bearing mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0102436

Mini Nutritional Assessment (MNA) and biochemical markers of cachexia in metastatic lung cancer patients: Interrelations and associations with prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0102436

Mechanisms and pathologic significances in increase in serum interleukin-6 (IL-6) and soluble IL-6 receptor after administration of an anti-IL-6 receptor antibody, tocilizumab, in patients with rheumatoid arthritis and Castleman disease

21 January 2018

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12 December 2020

Anti-interleukin-6 receptor antibody prevents muscle atrophy in colon-26 adenocarcinoma-bearing mice with modulation of lysosomal and ATP-ubiquitin-dependent proteolytic pathways

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12 December 2020

AIC model selection using Akaike weights

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12 December 2020

Reply to A. Berti et al

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12 December 2020

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12 December 2020

Drug treatments for metastasis of the Lewis lung carcinoma: lack of correlation between inhibition of lung metastasis and survival

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12 December 2020

Osteopontin induces angiogenesis of murine neuroblastoma cells in mice

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12 December 2020

Characterization of anti-mouse interleukin-6 receptor antibody

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12 December 2020

Studies in a tumor spectrum. III. The effect of phosphoramides on the growth of a variety of mouse and rat tumors

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12 December 2020

Acute-phase protein response and survival duration of patients with pancreatic cancer

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12 December 2020

10.1371/JOURNAL.PONE.0102436

Identifiers

DOI

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29 July 2017

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29 July 2017

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