Meal-related increases in microvascular vasomotion are impaired in obese individuals: a potential mechanism in the pathogenesis of obesity-related insulin resistance (Q33883164)

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English	Meal-related increases in microvascular vasomotion are impaired in obese individuals: a potential mechanism in the pathogenesis of obesity-related insulin resistance	scientific article

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scholarly article

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Europe PubMed Central

29 July 2017

Meal-related increases in microvascular vasomotion are impaired in obese individuals: a potential mechanism in the pathogenesis of obesity-related insulin resistance (English)

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Europe PubMed Central

29 July 2017

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1 reference

based on heuristic

inferred from title

insulin resistance

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based on heuristic

inferred from title

Peter W de Leeuw

4

object named as

Peter W de Leeuw

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Europe PubMed Central

29 July 2017

6

object named as

Yvo M Smulders

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Europe PubMed Central

29 July 2017

5

object named as

Erik H Serné

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Europe PubMed Central

29 July 2017

1

object named as

Amy M Jonk

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Europe PubMed Central

29 July 2017

Coenraad Dirk Adriaan Stehouwer

7

object named as

Coen D Stehouwer

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Europe PubMed Central

29 July 2017

Alfons J H M Houben

2

object named as

Alfons J Houben

1 reference

Europe PubMed Central

29 July 2017

Nicolaas Schaper

3

object named as

Nicolaas C Schaper

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Europe PubMed Central

29 July 2017

language of work or name

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publication date

1 May 2011

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Europe PubMed Central

29 July 2017

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Europe PubMed Central

29 July 2017

34 Suppl 2

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Europe PubMed Central

29 July 2017

S342-8

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Europe PubMed Central

29 July 2017

copyright license

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

28 August 2021

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April 2022 Public Data File from Crossref

copyright status

0 references

Muscle contraction, but not insulin, increases microvascular blood volume in the presence of free fatty acid-induced insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

5 July 2018

Infusing lipid raises plasma free fatty acids and induces insulin resistance in muscle microvasculature

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

5 July 2018

Decreased microvascular vasomotion and myogenic response in rat skeletal muscle in association with acute insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

5 July 2018

Adipose tissue dysfunction in obesity, diabetes, and vascular diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

5 July 2018

Vascular inflammation, insulin resistance, and reduced nitric oxide production precede the onset of peripheral insulin resistance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

5 July 2018

Tumor necrosis factor-alpha downregulates endothelial nitric oxide synthase mRNA stability via translation elongation factor 1-alpha 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

5 July 2018

Impaired microvascular perfusion: a consequence of vascular dysfunction and a potential cause of insulin resistance in muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

5 July 2018

Renin-angiotensin system, natriuretic peptides, obesity, metabolic syndrome, and hypertension: an integrated view in humans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

5 July 2018

Decreased NO signaling leads to enhanced vasoconstrictor responsiveness in skeletal muscle arterioles of the ZDF rat prior to overt diabetes and hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

5 July 2018

The human cutaneous circulation as a model of generalized microvascular function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

5 July 2018

Impaired local microvascular vasodilatory effects of insulin and reduced skin microvascular vasomotion in obese women

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

5 July 2018

Skeletal muscle capillary responses to insulin are abnormal in late-stage diabetes and are restored by angiotensin-converting enzyme inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

5 July 2018

Microvascular dysfunction in obesity: a potential mechanism in the pathogenesis of obesity-associated insulin resistance and hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

5 July 2018

Point: There is capillary recruitment in active skeletal muscle during exercise

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

5 July 2018

Regulation of vascular function and insulin sensitivity by adipose tissue: focus on perivascular adipose tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

5 July 2018

Microvascular dysfunction: a potential pathophysiological role in the metabolic syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

5 July 2018

Angiotensin II-induced NADPH oxidase activation impairs insulin signaling in skeletal muscle cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

5 July 2018

Obesity blunts insulin-mediated microvascular recruitment in human forearm muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

5 July 2018

Physiological concentrations of insulin induce endothelin-dependent vasoconstriction of skeletal muscle resistance arteries in the presence of tumor necrosis factor-alpha dependence on c-Jun N-terminal kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

5 July 2018

Skin blood flowmotion response to insulin iontophoresis in normal subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

5 July 2018

Endothelial dysfunction, inflammation, and insulin resistance: a focus on subjects at risk for type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

5 July 2018

Physiological hyperinsulinaemia increases intramuscular microvascular reactive hyperaemia and vasomotion in healthy volunteers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

5 July 2018

Use and abuse of HOMA modeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

5 July 2018

Oxidative stress induces insulin resistance by activating the nuclear factor-kappa B pathway and disrupting normal subcellular distribution of phosphatidylinositol 3-kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

5 July 2018

Vasoconstrictor effects of insulin in skeletal muscle arterioles are mediated by ERK1/2 activation in endothelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

5 July 2018

Elevation of free fatty acids induces inflammation and impairs vascular reactivity in healthy subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

5 July 2018

Blood flow and muscle metabolism: a focus on insulin action.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

5 July 2018

Capillary recruitment is impaired in essential hypertension and relates to insulin's metabolic and vascular actions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

5 July 2018

Insulin-induced vasodilatation: physiology or pharmacology?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

5 July 2018

Hemodynamic actions of insulin in rat skeletal muscle: evidence for capillary recruitment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

5 July 2018

Cross-talk between the insulin and angiotensin signaling systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

5 July 2018

Theoretical analysis of complex oscillations in multibranched microvascular networks.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

5 July 2018

Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

5 July 2018

Hemodynamic actions of insulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

5 July 2018

Rates and Tissue Sites of Noninsulin- and Insulin-Mediated Glucose Uptake in Diabetic Rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

5 July 2018

Endothelial and vascular dysfunctions and insulin resistance in rats fed a high-fat, high-sucrose diet

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

29 October 2018

TNF-alpha levels are associated with skin capillary recruitment in humans: a potential explanation for the relationship between TNF-alpha and insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

29 October 2018

Tumor necrosis factor-alpha induces skeletal muscle insulin resistance in healthy human subjects via inhibition of Akt substrate 160 phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

29 October 2018

"Vasocrine" signalling from perivascular fat: a mechanism linking insulin resistance to vascular disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

29 October 2018

Free fatty acid impairment of nitric oxide production in endothelial cells is mediated by IKKbeta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

29 October 2018

Free fatty acid levels modulate microvascular function: relevance for obesity-associated insulin resistance, hypertension, and microangiopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

29 October 2018

Impaired microvascular function in obesity: implications for obesity-associated microangiopathy, hypertension, and insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

29 October 2018

Enhanced vascular activity of endogenous endothelin-1 in obese hypertensive patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

29 October 2018

TNF-alpha acutely inhibits vascular effects of physiological but not high insulin or contraction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

29 October 2018

Physiological concentrations of insulin induce endothelin-mediated vasoconstriction during inhibition of NOS or PI3-kinase in skeletal muscle arterioles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

29 October 2018

Lipid infusion impairs physiologic insulin-mediated capillary recruitment and muscle glucose uptake in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

29 October 2018

Reduction of inflammatory cytokine concentrations and improvement of endothelial functions in obese women after weight loss over one year

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

29 October 2018

Insulin stimulates both endothelin and nitric oxide activity in the human forearm.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632204

29 October 2018

Acute impairment of insulin-mediated capillary recruitment and glucose uptake in rat skeletal muscle in vivo by TNF-alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/21525480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microcirculation in hypertension: a new target for treatment?

1 reference

https://pubmed.ncbi.nlm.nih.gov/21525480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reassessing the mathematical modeling of the contribution of vasomotion to vascular resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/21525480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of role for nitric oxide (NO) in the selective destabilization of endothelial NO synthase mRNA by tumor necrosis factor-alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/21525480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Body fat distribution predicts the degree of endothelial dysfunction in uncomplicated obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21525480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for two vascular pathways in skeletal muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/21525480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lower capillary density but no difference in VEGF expression in obese vs. lean young skeletal muscle in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/21525480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free fatty acids inhibit insulin signaling-stimulated endothelial nitric oxide synthase activation through upregulating PTEN or inhibiting Akt kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21525480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endocrine role of the renin-angiotensin system in human adipose tissue and muscle: effect of beta-adrenergic stimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21525480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of dietary composition on postprandial endothelial function and adiponectin concentrations in healthy humans: a crossover controlled study

1 reference

https://pubmed.ncbi.nlm.nih.gov/21525480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin increases angiotensinogen expression in human abdominal subcutaneous adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21525480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free fatty acid elevation impairs insulin-mediated vasodilation and nitric oxide production

1 reference

https://pubmed.ncbi.nlm.nih.gov/21525480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2337/DC11-S240

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

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