Antagonizing deactivating cytokines to enhance host defense and chemotherapy in experimental visceral leishmaniasis (Q33883498)

29 July 2017

title

Antagonizing deactivating cytokines to enhance host defense and chemotherapy in experimental visceral leishmaniasis (English)

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29 July 2017

main subject

visceral leishmaniasis

1 reference

1 reference

Henry W Murray

1

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29 July 2017

Kathleen C Flanders

2

1 reference

29 July 2017

Debra D Donaldson

3

1 reference

29 July 2017

Joseph P Sypek

4

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29 July 2017

Philip J Gotwals

5

1 reference

29 July 2017

Jianguo Liu

6

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29 July 2017

Xiaojing Ma

7

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29 July 2017

language of work or name

English

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publication date

1 July 2005

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29 July 2017

published in

Infection and Immunity

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29 July 2017

volume

73

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29 July 2017

issue

7

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29 July 2017

page(s)

3903-3911

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Regulation and role of transforming growth factor-beta in immune tolerance induction and inflammation.

29 July 2017

cites work

1 reference

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The immunopathology of experimental visceral leishmaniasis

28 July 2018

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Does the Leishmania major paradigm of pathogenesis and protection hold for New World cutaneous leishmaniases or the visceral disease?

28 July 2018

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Immunotherapy with OX40L-Fc or anti-CTLA-4 enhances local tissue responses and killing of Leishmania donovani.

28 July 2018

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Hepatic cellular immune responses in mice with "cure" and "non-cure" phenotype to Leishmania infantum infection: importance of CD8+ T cells and TGF-beta production

28 July 2018

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Immunoenhancement combined with amphotericin B as treatment for experimental visceral leishmaniasis

28 July 2018

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Both interleukin-4 (IL-4) and IL-4 receptor alpha signaling contribute to the development of hepatic granulomas with optimal antileishmanial activity

28 July 2018

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Enhanced interleukin (IL)-13 responses in mice lacking IL-13 receptor alpha 2.

28 July 2018

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The TGF-beta response to Leishmania chagasi in the absence of IL-12

28 July 2018

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Interleukin-10 (IL-10) in experimental visceral leishmaniasis and IL-10 receptor blockade as immunotherapy

28 July 2018

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Blockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases.

28 July 2018

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TGF-beta antagonists: why suppress a tumor suppressor?

28 July 2018

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Transforming growth factor-beta in T-cell biology

28 July 2018

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Mice lacking Smad3 are protected against cutaneous injury induced by ionizing radiation

28 July 2018

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Tissue granuloma structure-function in experimental visceral leishmaniasis

28 July 2018

1 reference

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IL-10 mediates susceptibility to Leishmania donovani infection.

28 July 2018

1 reference

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Interleukin-13 in Iranian patients with visceral leishmaniasis: relationship to other Th2 and Th1 cytokines

28 July 2018

1 reference

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Interleukin-10 and the interleukin-10 receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168607

Visceral leishmaniasis in mice devoid of tumor necrosis factor and response to treatment

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168607

Interleukin-12 regulates the response to chemotherapy in experimental visceral Leishmaniasis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168607

IL-13 is a susceptibility factor for Leishmania major infection.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168607

Roles of endogenous gamma interferon and macrophage microbicidal mechanisms in host response to chemotherapy in experimental visceral leishmaniasis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168607

Behavior of visceral Leishmania donovani in an experimentally induced T helper cell 2 (Th2)-associated response model

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168607

Th1 and Th2 cell-associated cytokines in experimental visceral leishmaniasis.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168607

In vivo cytokine profiles in patients with kala-azar. Marked elevation of both interleukin-10 and interferon-gamma

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168607

The regulation of immunity to Leishmania major

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168607

Modulation of T-Cell Costimulation as Immunotherapy or Immunochemotherapy in Experimental Visceral Leishmaniasis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168607

Determinants of response to interleukin-10 receptor blockade immunotherapy in experimental visceral leishmaniasis

29 October 2018

1 reference

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Dendritic cell-based immunotherapy combined with antimony-based chemotherapy cures established murine visceral leishmaniasis.

29 October 2018

1 reference

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Decoy receptors in the regulation of T helper cell type 2 responses

29 October 2018

1 reference

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Activation of TGF-beta by Leishmania chagasi: importance for parasite survival in macrophages

29 October 2018

1 reference

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An essential role for IL-13 in maintaining a non-healing response following Leishmania mexicana infection.

29 October 2018

1 reference

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IL-13 gene-deficient mice are susceptible to cutaneous L. mexicana infection

29 October 2018

1 reference

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Clinical and experimental advances in treatment of visceral leishmaniasis

29 October 2018

1 reference

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Activities of hexadecylphosphocholine (miltefosine), AmBisome, and sodium stibogluconate (Pentostam) against Leishmania donovani in immunodeficient scid mice

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168607

Endogenous IL-4 is necessary for effective drug therapy against visceral leishmaniasis

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168607

TGF-beta in infections and infectious diseases

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168607

An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory response

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168607

Differences between IL-4- and IL-4 receptor alpha-deficient mice in chronic leishmaniasis reveal a protective role for IL-13 receptor signaling

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168607

Anti-TGF-beta treatment promotes rapid healing of Leishmania major infection in mice by enhancing in vivo nitric oxide production.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168607

The importance of TGF-beta in murine visceral leishmaniasis.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168607

The role of IL-13 and its receptor in allergy and inflammatory responses.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168607

Neutralization of IL-12 demonstrates the existence of discrete organ-specific phases in the control of Leishmania donovani.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168607

High levels of plasma IL-10 and expression of IL-10 by keratinocytes during visceral leishmaniasis predict subsequent development of post-kala-azar dermal leishmaniasis

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168607

Cell-mediated immune response in experimental visceral leishmaniasis. I. Correlation between resistance to Leishmania donovani and lymphokine-generating capacity.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168607

Requirement for T cells and effect of lymphokines in successful chemotherapy for an intracellular infection. Experimental visceral leishmaniasis

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168607

Circulating T helper 1 (Th1) cell- and Th2 cell-associated cytokines in Indian patients with visceral leishmaniasis

29 October 2018

1 reference

12 December 2020

The capacity to produce IFN-gamma rather than the presence of interleukin-4 determines the resistance and the degree of susceptibility to Leishmania donovani infection in mice

1 reference

12 December 2020

Role and effect of TNF-alpha in experimental visceral leishmaniasis

1 reference

12 December 2020

Modulating ongoing Th2-cell responses in experimental leishmaniasis

1 reference

12 December 2020

Interleukin (IL)-13 is the predominant Th2 cytokine in localized cutaneous leishmaniasis lesions and renders specific CD4+ T cells unresponsive to IL-12

1 reference

12 December 2020

Infection pattern and immune response in the spleen and liver of BALB/c mice intracardially infected with Leishmania donovani amastigotes

1 reference

12 December 2020

Induction of Protective Th1 Responses toCandida albicansby Antifungal Therapy Alone or in Combination with an Interleukin‐4 Antagonist

1 reference

12 December 2020

Immunochemotherapy for intracellular Leishmania donovani infection: gamma interferon plus pentavalent antimony

1 reference

12 December 2020

IL-4-independent inhibition of IL-12 responsiveness during Leishmania amazonensis infection

1 reference

12 December 2020

IL-12 gene-deficient C57BL/6 mice are susceptible to Leishmania donovani but have diminished hepatic immunopathology

1 reference

12 December 2020

Interleukin-4 and interleukin-10 synergize to inhibit cell-mediated immunity in vivo

1 reference

12 December 2020

The hamster as a model of human visceral leishmaniasis: progressive disease and impaired generation of nitric oxide in the face of a prominent Th1-like cytokine response

1 reference

12 December 2020

Transforming growth factor-beta in leishmanial infection: a parasite escape mechanism

1 reference

12 December 2020

Expression of Th2 cytokines and the stable Th2 marker ST2L in the absence of IL-4 during Leishmania major infection

1 reference

12 December 2020

Leishmania donovani: evolution and architecture of the splenic cellular immune response related to control of infection

1 reference

12 December 2020

The Relative Contribution of IL-4 Receptor Signaling and IL-10 to Susceptibility toLeishmania major

1 reference

12 December 2020

Macrophage deactivating factor and transforming growth factors-beta 1 -beta 2 and -beta 3 inhibit induction of macrophage nitrogen oxide synthesis by IFN-gamma

1 reference

12 December 2020

10.1128/IAI.73.7.3903-3911.2005

Identifiers

DOI

1 reference

release_4jtcq3oeozdtjfvagscfsnaz7a

29 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/4jtcq3oeozdtjfvagscfsnaz7a

24 November 2022

mapped directly with Wikidata item

PMC publication ID

1168607

1 reference

29 July 2017

1 reference