Benzo[a]pyrene diol epoxide stimulates an inflammatory response in normal human lung fibroblasts through a p53 and JNK mediated pathway (Q33884603)

29 July 2017

title

Benzo[a]pyrene diol epoxide stimulates an inflammatory response in normal human lung fibroblasts through a p53 and JNK mediated pathway (English)

1 reference

29 July 2017

Kristian Dreij

1

1 reference

29 July 2017

Kahn Rhrissorrakrai

2

1 reference

29 July 2017

Kristin C Gunsalus

3

1 reference

29 July 2017

Nicholas E Geacintov

4

1 reference

29 July 2017

David A Scicchitano

5

1 reference

29 July 2017

language of work or name

English

0 references

publication date

9 April 2010

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29 July 2017

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29 July 2017

volume

31

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29 July 2017

issue

6

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29 July 2017

page(s)

1149-1157

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DNA repair in mammalian cells : Nucleotide excision repair: variations on versatility

29 July 2017

cites work

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Both replication bypass fidelity and repair efficiency influence the yield of mutations per target dose in intact mammalian cells induced by benzo[a]pyrene-diol-epoxide and dibenzo[a,l]pyrene-diol-epoxide

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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p53 regulates cellular responses to environmental carcinogen benzo[a]pyrene-7,8-diol-9,10-epoxide in human lung cancer cells

5 July 2018

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5 July 2018

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5 July 2018

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Busulfan-induced senescence is dependent on ROS production upstream of the MAPK pathway

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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An evaluation of the ability of pifithrin-alpha and -beta to inhibit p53 function in two wild-type p53 human tumor cell lines

5 July 2018

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Protective effects of aucubin isolated from Eucommia ulmoides against UVB-induced oxidative stress in human skin fibroblasts

5 July 2018

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Differential removal of DNA adducts derived from anti-diol epoxides of dibenzo[a,l]pyrene and benzo[a]pyrene in human cells.

5 July 2018

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Phenotypic anchoring of global gene expression profiles induced by N-hydroxy-4-acetylaminobiphenyl and benzo[a]pyrene diol epoxide reveals correlations between expression profiles and mechanism of toxicity

5 July 2018

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Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878364

Nuclear factor-kappaB: the enemy within

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878364

Tobacco smoke and involuntary smoking

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878364

Cigarette smoke induces cyclooxygenase-2 and microsomal prostaglandin E2 synthase in human lung fibroblasts: implications for lung inflammation and cancer

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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The effect of dibenzo[a,1]pyrene and benzo[a]pyrene on human diploid lung fibroblasts: the induction of DNA adducts, expression of p53 and p21(WAF1) proteins and cell cycle distribution

5 July 2018

1 reference

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Identification of genes responsive to BPDE treatment in HeLa cells using cDNA expression assays

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878364

A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878364

Tobacco smoke carcinogens and lung cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878364

The level of DNA modification by (+)-syn-(11S,12R,13S,14R)- and (-)-anti-(11R,12S,13S,14R)-dihydrodiol epoxides of dibenzo[a,l]pyrene determined the effect on the proteins p53 and p21WAF1 in the human mammary carcinoma cell line MCF-7.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878364

Stimulus-specific regulation of chemokine expression involves differential activation of the redox-responsive transcription factors AP-1 and NF-kappaB.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878364

A role for ATR in the DNA damage-induced phosphorylation of p53

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878364

Enhanced phosphorylation of p53 by ATM in response to DNA damage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878364

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

5 July 2018

1 reference

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The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation

5 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878364

5 July 2018

https://pubmed.ncbi.nlm.nih.gov/20382639

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The natural history of chronic airflow obstruction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878364

Benzo[a]pyrene induces intercellular adhesion molecule-1 through a caveolae and aryl hydrocarbon receptor mediated pathway

5 July 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ073

Interleukin-8 induction by the environmental contaminant benzo(a)pyrene is aryl hydrocarbon receptor-dependent and leads to lung inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ073

Response of human mammary epithelial cells to DNA damage induced by BPDE: involvement of novel regulatory pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ073

Gene expression profiles and genetic damage in benzo(a)pyrene diol epoxide-exposed TK6 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ073

Gene profiling of normal human bronchial epithelial cells in response to asbestos and benzo(a)pyrene diol epoxide (BPDE).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ073

Environmental polycyclic aromatic hydrocarbons, benzo(a) pyrene (BaP) and BaP-quinones, enhance IgE-mediated histamine release and IL-4 production in human basophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ073

Benzo[a]pyrene and its metabolites combined with ultraviolet A synergistically induce 8-hydroxy-2'-deoxyguanosine via reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ073

Benzo[a]pyrene diol epoxide up-regulates COX-2 expression through NF-kappaB in rat astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ073

Benzo[a]pyrene diol-epoxide (B[a]PDE) upregulates COX-2 expression through MAPKs/AP-1 and IKKbeta/NF-kappaB in mouse epidermal Cl41 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ073

p53 controls global nucleotide excision repair of low levels of structurally diverse benzo(g)chrysene-DNA adducts in human fibroblasts

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878364

Metabolic activation of benzo(a)pyrene proceeds by a diol-epoxide

29 October 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ073

The Ah regulatory gene product. Survey of nineteen polycyclic aromatic compounds' and fifteen benzo[a]pyrene metabolites' capacity to bind to the cytosolic receptor

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20382639

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/CARCIN/BGQ073

1 reference

29 July 2017

1 reference

29 July 2017

1 reference