AGEs decrease insulin synthesis in pancreatic β-cell by repressing Pdx-1 protein expression at the post-translational level (Q33886522)

29 July 2017

AGEs decrease insulin synthesis in pancreatic β-cell by repressing Pdx-1 protein expression at the post-translational level (English)

1 reference

29 July 2017

1 reference

Tingting Shu

1

1 reference

29 July 2017

Yunxia Zhu

2

1 reference

29 July 2017

Hongdong Wang

3

1 reference

29 July 2017

Yan Lin

4

1 reference

29 July 2017

Zhuo Ma

5

1 reference

29 July 2017

Xiao Han

6

1 reference

29 July 2017

language of work or name

English

0 references

publication date

18 April 2011

1 reference

29 July 2017

1 reference

29 July 2017

6

1 reference

29 July 2017

4

1 reference

29 July 2017

e18782

1 reference

Creative Commons Attribution 4.0 International

29 July 2017

start time

18 April 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Advanced glycation end-products affect transcription factors regulating insulin gene expression

5 July 2018

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Forkhead box O1/pancreatic and duodenal homeobox 1 intracellular translocation is regulated by c-Jun N-terminal kinase and involved in prostaglandin E2-induced pancreatic beta-cell dysfunction

5 July 2018

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Inhibition of forkhead box O1 protects pancreatic beta-cells against dexamethasone-induced dysfunction

5 July 2018

1 reference

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Advanced glycation end products inhibit glucose-stimulated insulin secretion through nitric oxide-dependent inhibition of cytochrome c oxidase and adenosine triphosphate synthesis

5 July 2018

1 reference

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Induction of apoptosis of Beta cells of the pancreas by advanced glycation end-products, important mediators of chronic complications of diabetes mellitus

5 July 2018

1 reference

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Interaction of the RAGE cytoplasmic domain with diaphanous-1 is required for ligand-stimulated cellular migration through activation of Rac1 and Cdc42

5 July 2018

1 reference

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Role of AGEs in diabetic nephropathy

5 July 2018

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Glucolipotoxicity: fuel excess and beta-cell dysfunction.

5 July 2018

1 reference

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PDX-1 and MafA play a crucial role in pancreatic beta-cell differentiation and maintenance of mature beta-cell function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078922

Role of FoxO Proteins in Pancreatic beta Cells

5 July 2018

1 reference

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Pancreatic islet beta-cell and oxidative stress: the importance of glutathione peroxidase

5 July 2018

1 reference

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Prostaglandin E2 regulates Foxo activity via the Akt pathway: implications for pancreatic islet beta cell dysfunction

5 July 2018

1 reference

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5 July 2018

1 reference

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Phosphorylation marks IPF1/PDX1 protein for degradation by glycogen synthase kinase 3-dependent mechanisms

5 July 2018

1 reference

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The forkhead transcription factor Foxo1 bridges the JNK pathway and the transcription factor PDX-1 through its intracellular translocation

5 July 2018

1 reference

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Advanced glycation end products and RAGE: a common thread in aging, diabetes, neurodegeneration, and inflammation

5 July 2018

1 reference

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Mechanism of insulin gene regulation by the pancreatic transcription factor Pdx-1: application of pre-mRNA analysis and chromatin immunoprecipitation to assess formation of functional transcriptional complexes

5 July 2018

1 reference

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Chronic oxidative stress as a central mechanism for glucose toxicity in pancreatic islet beta cells in diabetes

5 July 2018

1 reference

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The receptor for advanced glycation end-products (RAGE) directly binds to ERK by a D-domain-like docking site

5 July 2018

1 reference

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Glucose toxicity in beta-cells: type 2 diabetes, good radicals gone bad, and the glutathione connection

5 July 2018

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The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth

5 July 2018

1 reference

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Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078922

Diabetes and advanced glycation endproducts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078922

Advanced glycation end products cause epithelial-myofibroblast transdifferentiation via the receptor for advanced glycation end products (RAGE)

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078922

Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078922

Age, neurofibrillary changes, A beta-amyloid and the onset of Alzheimer's disease

5 July 2018

1 reference

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Type 2 diabetes-a matter of beta-cell life and death?

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018782

Relationship between proinsulin-to-insulin ratio and advanced glycation endproducts in Japanese type 2 diabetic subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018782

Inhibition of advanced glycation end products: an implicit goal in clinical medicine for the treatment of diabetic nephropathy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018782

Improved glucose tolerance and acinar dysmorphogenesis by targeted expression of transcription factor PDX-1 to the exocrine pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018782

Reduced PDX-1 expression impairs islet response to insulin resistance and worsens glucose homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018782

Tissue inhibitor of metalloproteinase-1 prevents cytokine-mediated dysfunction and cytotoxicity in pancreatic islets and beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018782

Advanced glycation end products induce apoptosis in fibroblasts through activation of ROS, MAP kinases, and the FOXO1 transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018782

Methylglyoxal induces advanced glycation end product (AGEs) formation and dysfunction of PDGF receptor-beta: implications for diabetic atherosclerosis

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21533167

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0018782

1 reference

release_rusxc2r25jafzaqfqnlhoiptsa

29 July 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/rusxc2r25jafzaqfqnlhoiptsa

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMCID

3078922

1 reference

29 July 2017

1 reference