Polyglutamine expansion down-regulates specific neuronal genes before pathologic changes in SCA1. (Q33887926)

29 July 2017

title

Polyglutamine expansion down-regulates specific neuronal genes before pathologic changes in SCA1. (English)

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29 July 2017

5

H Y Zoghbi

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29 July 2017

X Lin

1

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29 July 2017

B Antalffy

series ordinal

2

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29 July 2017

D Kang

series ordinal

3

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29 July 2017

H T Orr

series ordinal

4

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29 July 2017

language of work or name

English

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publication date

1 February 2000

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29 July 2017

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29 July 2017

volume

3

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29 July 2017

issue

2

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29 July 2017

page(s)

157-163

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Spinocerebellar ataxia type 1

29 July 2017

cites work

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SCA1 transgenic mice: A model for neurodegeneration caused by an expanded CAG trinucleotide repeat

21 January 2018

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Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures

21 January 2018

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Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice

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Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum

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Genes encoding farnesyl cysteine carboxyl methyltransferase in Schizosaccharomyces pombe and Xenopus laevis

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Regulation of second messengers by the inositol polyphosphate 5-phosphatases

21 January 2018

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Comparison of neuronal inositol 1,4,5-trisphosphate 3-kinase and receptor mRNA distributions in the adult rat brain using in situ hybridization histochemistry

21 January 2018

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Expression of rat cGMP-binding cGMP-specific phosphodiesterase mRNA in Purkinje cell layers during postnatal neuronal development

21 January 2018

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Isolation of two cDNAs encoding novel α1-antichymotrypsin-like proteins in a murine chondrocytic cell line

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Mutation of the Angelman ubiquitin ligase in mice causes increased cytoplasmic p53 and deficits of contextual learning and long-term potentiation.

21 January 2018

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Immunochemical identification of the serine protease inhibitor alpha 1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease

21 January 2018

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Expression of the Alzheimer amyloid-promoting factor antichymotrypsin is induced in human astrocytes by IL-1.

21 January 2018

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Developmental expression of alpha 1-antichymotrypsin in brain may be related to astrogliosis.

21 January 2018

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Extra-junctional localization of glutamate transporter EAAT4 at excitatory Purkinje cell synapses

21 January 2018

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On the molecular basis and regulation of cellular capacitative calcium entry: roles for Trp proteins.

21 January 2018

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trp, a novel mammalian gene family essential for agonist-activated capacitative Ca2+ entry

21 January 2018

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The family of inositol and phosphatidylinositol polyphosphate 5-phosphatases

21 January 2018

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Cloning and expression of human brain type I inositol 1,4,5-trisphosphate 5-phosphatase. High levels of mRNA in cerebellar Purkinje cells

21 January 2018

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The endoplasmic reticulum of Purkinje neuron body and dendrites: molecular identity and specializations for Ca2+ transport

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Ataxia and epileptic seizures in mice lacking type 1 inositol 1,4,5-trisphosphate receptor.

21 January 2018

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Three additional inositol 1,4,5-trisphosphate receptors: molecular cloning and differential localization in brain and peripheral tissues

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Neuronal calcium signaling

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Calcium and neuronal ageing

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Chemical biology of protein isoprenylation/methylation

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Protein isoprenylation and methylation at carboxyl-terminal cysteine residues

21 January 2018

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Modification of eukaryotic signaling proteins by C-terminal methylation reactions

21 January 2018

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Endomembrane trafficking of ras: the CAAX motif targets proteins to the ER and Golgi

21 January 2018

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Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1.

21 January 2018

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The ubiquitin-proteasome proteolytic pathway

21 January 2018

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Proteasome-dependent degradation of the human estrogen receptor

21 January 2018

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Proteasomal regulation of nuclear receptor corepressor-mediated repression

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Modulation of CREB binding protein function by the promyelocytic (PML) oncoprotein suggests a role for nuclear bodies in hormone signaling

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Mice lacking ataxin-1 display learning deficits and decreased hippocampal paired-pulse facilitation

21 January 2018

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7 January 2021

Purkinje cell expression of a mutant allele of SCA1 in transgenic mice leads to disparate effects on motor behaviors, followed by a progressive cerebellar dysfunction and histological alterations.

1 reference

7 January 2021

EAAT4 is a post-synaptic glutamate transporter at Purkinje cell synapses

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7 January 2021

The rat phospholipase C beta 4 gene is expressed at high abundance in cerebellar Purkinje cells.

1 reference

7 January 2021

Neurotrophic regulation of mouse muscle beta-amyloid protein precursor and alpha 1-antichymotrypsin as revealed by axotomy

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7 January 2021

Inositol lipid 5-phosphatases--traffic signals and signal traffic.

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7 January 2021

Ca2+ stores in Purkinje neurons: endoplasmic reticulum subcompartments demonstrated by the heterogeneous distribution of the InsP3 receptor, Ca(2+)-ATPase, and calsequestrin

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7 January 2021

Multiple/heterogeneous Ca2+ stores in cerebellum Purkinje neurons

1 reference

7 January 2021

The type 1 inositol 1,4,5-trisphosphate receptor gene is altered in the opisthotonos mouse

1 reference

7 January 2021

Localization of an endoplasmic reticulum calcium ATPase mRNA in rat brain by in situ hybridization

1 reference

7 January 2021

Immunohistochemical localization of an inositol 1,4,5-trisphosphate receptor, P400, in neural tissue: studies in developing and adult mouse brain

1 reference

7 January 2021

Consequences of functional expression of the plasma membrane Ca2+ pump isoform 1a

1 reference

7 January 2021

Identifiers

DOI

10.1038/72101

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Dimensions Publication ID

29 July 2017

1009302936

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