Kinetic characterization of ebselen, chelerythrine and apomorphine as glutaminase inhibitors (Q33889353)

29 July 2017

title

Kinetic characterization of ebselen, chelerythrine and apomorphine as glutaminase inhibitors (English)

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29 July 2017

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5

Anton Simeonov

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29 July 2017

10

Barbara S Slusher

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29 July 2017

1

Ajit G Thomas

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29 July 2017

Camilo Rojas

2

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29 July 2017

Cordelle Tanega

3

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29 July 2017

Min Shen

4

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29 July 2017

Matthew B Boxer

6

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29 July 2017

Douglas S Auld

7

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29 July 2017

Dana V Ferraris

8

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29 July 2017

Takashi Tsukamoto

9

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29 July 2017

language of work or name

English

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publication date

10 July 2013

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Biochemical and Biophysical Research Communications

29 July 2017

published in

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29 July 2017

volume

438

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29 July 2017

issue

2

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29 July 2017

page(s)

243-248

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Design, synthesis, and pharmacological evaluation of bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide 3 (BPTES) analogs as glutaminase inhibitors.

29 July 2017

cites work

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Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism

5 July 2018

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Dibenzophenanthridines as inhibitors of glutaminase C and cancer cell proliferation.

5 July 2018

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Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism

5 July 2018

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Full-length human glutaminase in complex with an allosteric inhibitor

5 July 2018

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Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1.

5 July 2018

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Targeting mitochondrial glutaminase activity inhibits oncogenic transformation

5 July 2018

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Sanguinarine as a potent and specific inhibitor of protein phosphatase 2C in vitro and induces apoptosis via phosphorylation of p38 in HL60 cells

5 July 2018

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Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer

5 July 2018

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Glutamine in neoplastic cells: focus on the expression and roles of glutaminases

5 July 2018

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c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

5 July 2018

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13C MR spectroscopy measurements of glutaminase activity in human hepatocellular carcinoma cells using hyperpolarized 13C-labeled glutamine

5 July 2018

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Differential effect of sanguinarine, chelerythrine and chelidonine on DNA damage and cell viability in primary mouse spleen cells and mouse leukemic cells

5 July 2018

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Glutamate production by HIV-1 infected human macrophage is blocked by the inhibition of glutaminase

5 July 2018

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Ebselen, a seleno-organic antioxidant, as an electrophile

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094369

Highly stable phenanthridinium frameworks as a new class of tunable DNA binding agents with cytotoxic properties

5 July 2018

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Mitochondrial glutaminase enhances extracellular glutamate production in HIV-1-infected macrophages: linkage to HIV-1 associated dementia.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094369

The apomorphine test: a biological marker for heroin dependence disorder?

5 July 2018

1 reference

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Differential actions of antiparkinson agents at multiple classes of monoaminergic receptor. I. A multivariate analysis of the binding profiles of 14 drugs at 21 native and cloned human receptor subtypes

5 July 2018

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The glutamine commute: take the N line and transfer to the A

5 July 2018

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Subcutaneous apomorphine in Parkinson's disease

5 July 2018

1 reference

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Ebselen in acute ischemic stroke: a placebo-controlled, double-blind clinical trial. Ebselen Study Group

5 July 2018

1 reference

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Pharmacological activities of Chelidonium majus L. (Papaveraceae).

5 July 2018

1 reference

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Benzo[c]phenanthridine alkaloids sanguinarine and chelerythrine: biological activities and dental care applications

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094369

Molecular actions of Ebselen—an antiinflammatory antioxidant

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094369

Phase I study of 6-diazo-5-oxo-L-norleucine (DON).

5 July 2018

1 reference

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Phase I and pharmacokinetic studies of DON

5 July 2018

1 reference

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Phase I trial of 6-diazo-5-oxo-L-norleucine (DON) administered by 5-day courses

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094369

5 July 2018

Glutamine binding sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094369

Inactivation of rat renal phosphate-dependent glutaminase with 6-diazo-5-oxo-L-norleucine. Evidence for interaction at the glutamine binding site

5 July 2018

1 reference

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BPTES inhibition of hGA(124-551), a truncated form of human kidney-type glutaminase.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094369

Blockade of glutamate release from microglia attenuates experimental autoimmune encephalomyelitis in mice

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094369

Blockade of microglial glutamate release protects against ischemic brain injury

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094369

Kinetic studies of the radical-scavenging activity of ebselen, a seleno-organic compound.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094369

Properties of glutaminase of crayfish CNS: implications for axon-glia signaling

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094369

Ebselen in acute middle cerebral artery occlusion: a placebo-controlled, double-blind clinical trial

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094369

Neuroprotective effect of an antioxidant, ebselen, in patients with delayed neurological deficits after aneurysmal subarachnoid hemorrhage

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094369

In Vivo Release from Cerebral Cortex of [14C]Glutamate Synthesized from [U-14C]Glutamine

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094369

Chelerythrine chloride induces rapid polymorphonuclear leukocyte apoptosis through activation of caspase-3

29 October 2018

1 reference

12 December 2020

Glutaminase A of escherichia coli. Reactions with the substrate analogue, 6-diazo-5-oxonorleucine

1 reference

12 December 2020

Inhibition of liver alanine aminotransferase activity by some benzophenanthridine alkaloids

1 reference

12 December 2020

Neuroprotective effects of ebselen following forebrain ischemia: involvement of glutamate and nitric oxide

1 reference

12 December 2020

Implementation of a continuous, enzyme-coupled fluorescence assay for high-throughput analysis of glutamate-producing enzymes

1 reference

12 December 2020

10.1016/J.BBRC.2013.06.110

Identifiers

DOI

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29 July 2017

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29 July 2017

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