High glucose inhibits glucose-6-phosphate dehydrogenase, leading to increased oxidative stress and beta-cell apoptosis (Q33890987)

29 July 2017

High glucose inhibits glucose-6-phosphate dehydrogenase, leading to increased oxidative stress and beta-cell apoptosis (English)

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29 July 2017

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9

Joseph Loscalzo

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29 July 2017

Zhaoyun Zhang

1

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29 July 2017

Chong Wee Liew

2

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29 July 2017

Diane E Handy

3

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29 July 2017

Yingyi Zhang

4

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29 July 2017

Jane A Leopold

5

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29 July 2017

Ji Hu

6

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29 July 2017

Lili Guo

7

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29 July 2017

Rohit N Kulkarni

8

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29 July 2017

Robert C Stanton

10

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29 July 2017

language of work or name

English

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publication date

23 December 2009

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29 July 2017

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29 July 2017

24

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29 July 2017

1497-1505

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29 July 2017

5

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describes a project that uses

29 July 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2879949/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Beta-cell apoptosis in type 2 diabetes: quantitative and functional consequences.

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Oxidative stress as a major culprit in kidney disease in diabetes

5 July 2018

1 reference

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Oxidative stress: the vulnerable beta-cell

5 July 2018

1 reference

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Caspase-3 activation is a critical determinant of genotoxic stress-induced apoptosis

5 July 2018

1 reference

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Update in type 1 diabetes

5 July 2018

1 reference

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Pancreatic islet beta-cell and oxidative stress: the importance of glutathione peroxidase

5 July 2018

1 reference

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beta-cell failure in diabetes and preservation by clinical treatment

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879949

Increase in glucose-6-phosphate dehydrogenase in adipocytes stimulates oxidative stress and inflammatory signals

5 July 2018

1 reference

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A pyruvate cycling pathway involving cytosolic NADP-dependent isocitrate dehydrogenase regulates glucose-stimulated insulin secretion

5 July 2018

1 reference

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Glucose-6-phosphate dehydrogenase activity and NADPH/NADP+ ratio in liver and pancreas are dependent on the severity of hyperglycemia in rat

5 July 2018

1 reference

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Prevention of oxidative stress by adenoviral overexpression of glutathione-related enzymes in pancreatic islets

5 July 2018

1 reference

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Oxidative stress-mediated, post-translational loss of MafA protein as a contributing mechanism to loss of insulin gene expression in glucotoxic beta cells

5 July 2018

1 reference

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Chronic oxidative stress as a central mechanism for glucose toxicity in pancreatic islet beta cells in diabetes

5 July 2018

1 reference

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Beta-cell glucose toxicity, lipotoxicity, and chronic oxidative stress in type 2 diabetes

5 July 2018

1 reference

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Glucose-6-phosphate dehydrogenase modulates vascular endothelial growth factor-mediated angiogenesis

5 July 2018

1 reference

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Protection of insulin-secreting INS-1 cells against oxidative stress through adenoviral-mediated glutathione peroxidase overexpression

5 July 2018

1 reference

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Diabetes, oxidative stress, and antioxidants: a review

5 July 2018

1 reference

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Glucose-6-phosphate dehydrogenase overexpression decreases endothelial cell oxidant stress and increases bioavailable nitric oxide

5 July 2018

1 reference

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Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

5 July 2018

1 reference

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A role for glutathione peroxidase in protecting pancreatic beta cells against oxidative stress in a model of glucose toxicity

5 July 2018

1 reference

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Reduced beta-cell mass and expression of oxidative stress-related DNA damage in the islet of Japanese Type II diabetic patients.

5 July 2018

1 reference

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Importance of glucose-6-phosphate dehydrogenase activity in cell death

5 July 2018

1 reference

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Adenovirus-mediated catalase gene transfer reduces oxidant stress in human, porcine and rat pancreatic islets

5 July 2018

1 reference

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Importance of glucose-6-phosphate dehydrogenase activity for cell growth

5 July 2018

1 reference

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Relation between antioxidant enzyme gene expression and antioxidative defense status of insulin-producing cells

5 July 2018

1 reference

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Enhanced expression of glucose-6-phosphate dehydrogenase in human cells sustaining oxidative stress

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879949

A glucose-6-phosphate dehydrogenase (G6PD) splice site consensus sequence mutation associated with G6PD enzyme deficiency

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879949

The murine Ki-67 cell proliferation antigen accumulates in the nucleolar and heterochromatic regions of interphase cells and at the periphery of the mitotic chromosomes in a process essential for cell cycle progression

5 July 2018

1 reference

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A new lease of life for an old enzyme

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879949

5 July 2018

Proliferation markers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879949

Signal transduction proteins that associate with the platelet-derived growth factor (PDGF) receptor mediate the PDGF-induced release of glucose-6-phosphate dehydrogenase from permeabilized cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879949

Targeted disruption of the housekeeping gene encoding glucose 6-phosphate dehydrogenase (G6PD): G6PD is dispensable for pentose synthesis but essential for defense against oxidative stress

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879949

Effect of 6-aminonicotinamide on insulin release and C-14 glucose oxidation by isolated pancreatic rat islets: difference between glucose, tolbutamide and aminophylline.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879949

The role of the pentose phosphate shunt in glucose induced insulin release: in vitro studies with 6-aminonicotinamide, methylene blue, NAD + , NADH, NADP + , NADPH and nicotinamide on isolated pancreatic rat islets.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879949

X-linked glucose-6-phosphate dehydrogenase deficiency in Mus musculus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879949

Glucose-6-phosphate dehydrogenase deficiency decreases vascular superoxide and atherosclerotic lesions in apolipoprotein E(-/-) mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879949

Differentially expressed proteins in the pancreas of diet-induced diabetic mice

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879949

Diabetes causes inhibition of glucose-6-phosphate dehydrogenase via activation of PKA, which contributes to oxidative stress in rat kidney cortex

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879949

Pancreatic islets from type 2 diabetic patients have functional defects and increased apoptosis that are ameliorated by metformin.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879949

Glucose-6-phosphate dehydrogenase modulates cytosolic redox status and contractile phenotype in adult cardiomyocytes

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879949

Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879949

Mechanisms of protection of catalase by NADPH. Kinetics and stoichiometry

29 October 2018

1 reference

12 December 2020

High glucose inhibits glucose-6-phosphate dehydrogenase via cAMP in aortic endothelial cells

1 reference

12 December 2020

6-Amnionicotinamide (6-AN) as a diabetogenic agent. In vitro and in vivo studies in the rat

1 reference

12 December 2020

An improved method for isolation of mouse pancreatic islets

1 reference

12 December 2020

Upregulation of glucose-6-phosphate dehydrogenase and NAD(P)H oxidase activity increases oxidative stress in failing human heart

1 reference

12 December 2020

Chronic oxidative stress as a mechanism for glucose toxicity of the beta cell in type 2 diabetes

1 reference

12 December 2020

Complementary action of antioxidant enzymes in the protection of bioengineered insulin-producing RINm5F cells against the toxicity of reactive oxygen species

1 reference

12 December 2020

Role of oxidative stress in diabetic complications: a new perspective on an old paradigm

1 reference

12 December 2020

Enhanced glutathione levels and oxidoresistance mediated by increased glucose-6-phosphate dehydrogenase expression

1 reference

12 December 2020

Identifiers

DOI

10.1096/FJ.09-136572

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29 July 2017

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29 July 2017

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