The ETV6-NTRK3 gene fusion encodes a chimeric protein tyrosine kinase that transforms NIH3T3 cells (Q33892265)

29 July 2017

The ETV6-NTRK3 gene fusion encodes a chimeric protein tyrosine kinase that transforms NIH3T3 cells (English)

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29 July 2017

Wai DH

1

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29 July 2017

Knezevich SR

2

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29 July 2017

Lucas T

3

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29 July 2017

Jansen B

4

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29 July 2017

Kay RJ

5

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29 July 2017

Sorensen PH

6

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29 July 2017

language of work or name

English

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publication date

1 February 2000

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29 July 2017

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29 July 2017

19

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29 July 2017

7

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29 July 2017

906-915

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1203396

29 July 2017

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cites work

Deletion of part of the short arm of chromosome 17 in a congenital fibrosarcoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

Genomic organization of TEL: the human ETS-variant gene 6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

The Trk family of neurotrophin receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

Structural and functional properties of the TRK family of neurotrophin receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

Inositol trisphosphate and calcium signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

Caveolin interacts with Trk A and p75(NTR) and regulates neurotrophin signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

The TEL/platelet-derived growth factor beta receptor (PDGF beta R) fusion in chronic myelomonocytic leukemia is a transforming protein that self-associates and activates PDGF beta R kinase-dependent signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

ETV6 is the target of chromosome 12p deletions in t(12;21) childhood acute lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

Inositol-lipid-specific phospholipase C isoenzymes and their differential regulation by receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

Neurotrophin regulation of the developing nervous system: analyses of knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

Neurotrophins and their receptors in nerve injury and repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

Oligomerization of the ABL tyrosine kinase by the Ets protein TEL in human leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

Naturally occurring tyrosine kinase inserts block high affinity binding of phospholipase C gamma and Shc to TrkC and neurotrophin-3 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

Analysis of mitogen-activated protein kinase activation by naturally occurring splice variants of TrkC, the receptor for neurotrophin-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

Grb2-associated binder-1 mediates phosphatidylinositol 3-kinase activation and the promotion of cell survival by nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

Genomic characterization of the human trkC gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

Nerve growth factor mediates signal transduction through trk homodimer receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

Signal transduction by the neurotrophin receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

A novel ETV6-NTRK3 gene fusion in congenital fibrosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

The ets family member Tel binds to the Fli-1 oncoprotein and inhibits its transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

Significance of PIP2 hydrolysis and regulation of phospholipase C isozymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

Regulation of signal transduction and signal diversity by receptor oligomerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

Molecular cloning of the cDNA for human TrkC (NTRK3), chromosomal assignment, and evidence for a splice variant

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

Abnormalities of the ETV6 gene occur in the majority of patients with aberrations of the short arm of chromosome 12: a combined PCR and Southern blotting analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

Suc1-associated neurotrophic factor target (SNT) protein is a major FGF-stimulated tyrosine phosphorylated 90-kDa protein which binds to the SH2 domain of GRB2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

Production of high-titer helper-free retroviruses by transient transfection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

Analysis of TEL proteins in human leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

The TEL gene products: nuclear phosphoproteins with DNA binding properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

Identification and characterization of novel substrates of Trk receptors in developing neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

SNT, a differentiation-specific target of neurotrophic factor-induced tyrosine kinase activity in neurons and PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

Congenital mesoblastic nephroma t(12;15) is associated with ETV6-NTRK3 gene fusion: cytogenetic and molecular relationship to congenital (infantile) fibrosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

Consistent numerical chromosome aberrations in congenital fibrosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

Cytogenetic investigation of a case of congenital fibrosarcoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

A t(6;12)(q23;p13) results in the fusion of ETV6 to a novel gene, STL, in a B-cell ALL cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

The rat trkC locus encodes multiple neurogenic receptors that exhibit differential response to neurotrophin-3 in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

Alternative forms of rat TrkC with different functional capabilities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

Yolk sac angiogenic defect and intra-embryonic apoptosis in mice lacking the Ets-related factor TEL

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

The TEL/ETV6 gene is required specifically for hematopoiesis in the bone marrow

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

Fusion of TEL/ETV6 to a novel ACS2 in myelodysplastic syndrome and acute myelogenous leukemia with t(5;12)(q31;p13)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

Nerve growth factor induced stimulation of Ras requires Trk interaction with Shc but does not involve phosphoinositide 3-OH kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

Neurotrophic factors and their receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

7 January 2021

So-called congenital-infantile fibrosarcoma: does it exist and what is it?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

7 January 2021

Autophosphorylation of activation loop tyrosines regulates signaling by the TRK nerve growth factor receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

7 January 2021

The fusion of TEL and ABL in human acute lymphoblastic leukaemia is a rare event

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

7 January 2021

trkC encodes multiple neurotrophin-3 receptors with distinct biological properties and substrate specificities

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

7 January 2021

Nonrandom numerical chromosome aberrations (+8, +11, +17, +20) in infantile fibrosarcoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

7 January 2021

Protein kinase C and lipid signaling for sustained cellular responses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

7 January 2021

Deletion of a conserved juxtamembrane sequence in Trk abolishes NGF-promoted neuritogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

7 January 2021

TrkC isoforms with inserts in the kinase domain show impaired signaling responses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203396

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203396

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Dimensions Publication ID

29 July 2017

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