Effect of HIV integrase inhibitors on the RAG1/2 recombinase (Q33896796)

29 July 2017

title

Effect of HIV integrase inhibitors on the RAG1/2 recombinase (English)

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6

Yves Pommier

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7

Nouri Neamati

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29 July 2017

Meni Melek

1

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Jessica M Jones

2

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29 July 2017

Mary H O'Dea

3

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29 July 2017

Godwin Pais

4

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29 July 2017

Terrence R Burke

5

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29 July 2017

Martin Gellert

8

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29 July 2017

language of work or name

English

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publication date

26 December 2001

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Proceedings of the National Academy of Sciences of the United States of America

29 July 2017

published in

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volume

99

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issue

1

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page(s)

134-137

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describes a project that uses

29 July 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC117527/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Intermediates in V(D)J recombination: a stable RAG1/2 complex sequesters cleaved RSS ends.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=117527

HIV integrase, a brief overview from chemistry to therapeutics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=117527

HIV-1 integrase inhibitors: past, present, and future

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=117527

Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=117527

Mutations of acidic residues in RAG1 define the active site of the V(D)J recombinase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=117527

Mutational analysis of RAG1 and RAG2 identifies three catalytic amino acids in RAG1 critical for both cleavage steps of V(D)J recombination

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=117527

Structure of the HIV-1 integrase catalytic domain complexed with an inhibitor: a platform for antiviral drug design

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=117527

A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=117527

DNA transposition by the RAG1 and RAG2 proteins: a possible source of oncogenic translocations

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=117527

Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=117527

Assembly of a 12/23 paired signal complex: a critical control point in V(D)J recombination

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=117527

Recent advances in understanding V(D)J recombination.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=117527

RAG1 and RAG2 form a stable postcleavage synaptic complex with DNA containing signal ends in V(D)J recombination

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=117527

The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)J recombination

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=117527

Impairment of V(D)J recombination in double-strand break repair mutants

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=117527

Formation and resolution of double-strand break intermediates in V(D)J rearrangement

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=117527

Reversal of Integration and DNA Splicing Mediated by Integrase of Human Immunodeficiency Virus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=117527

Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps.

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.012610699

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.012610699

Rejoining of DNA by the RAG1 and RAG2 proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.012610699

RAG1/2-mediated resolution of transposition intermediates: two pathways and possible consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.012610699

21 January 2018

Identifiers

DOI

10.1073/PNAS.012610699

1 reference

29 July 2017

0 references

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29 July 2017

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