IDH1 and IDH2 gene mutations identify novel molecular subsets within de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study (Q33897586)

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English	IDH1 and IDH2 gene mutations identify novel molecular subsets within de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study	scientific article

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scholarly article

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Europe PubMed Central

29 July 2017

IDH1 and IDH2 gene mutations identify novel molecular subsets within de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study (English)

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Europe PubMed Central

29 July 2017

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based on heuristic

inferred from title

acute myeloid leukemia

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based on heuristic

inferred from title

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Thomas H Carter

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Klaus H Metzeler

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Klaus H Metzeler

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Richard A. Larson

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Richard A Larson

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Guido Marcucci

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29 July 2017

Clara D. Bloomfield

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Clara D Bloomfield

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Krzysztof Mrózek

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Krzysztof Mrózek

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29 July 2017

2

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Kati Maharry

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29 July 2017

Michael A Caligiuri

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object named as

Michael A Caligiuri

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29 July 2017

Jonathan E Kolitz

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Jonathan E Kolitz

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Meir Wetzler

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29 July 2017

Kelsi B Holland

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Kelsi B Holland

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29 July 2017

Bayard L Powell

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Bayard L Powell

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object named as

Heiko Becker

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Dean Margeson

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Sebastian Schwind

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Sebastian Schwind

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29 July 2017

author name string

Yue-Zhong Wu

3

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29 July 2017

Michael D Radmacher

4

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29 July 2017

Susan P Whitman

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Europe PubMed Central

29 July 2017

Andrew J Carroll

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29 July 2017

Maria R Baer

17

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29 July 2017

language of work or name

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publication date

5 April 2010

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Europe PubMed Central

29 July 2017

Journal of Clinical Oncology

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29 July 2017

28

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Europe PubMed Central

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14

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Europe PubMed Central

29 July 2017

2348-2355

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Europe PubMed Central

29 July 2017

Favorable prognostic impact of NPM1 mutations in older patients with cytogenetically normal de novo acute myeloid leukemia and associated gene- and microRNA-expression signatures: a Cancer and Leukemia Group B study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881719

28 July 2018

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881719

28 July 2018

Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet

1 reference

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28 July 2018

MicroRNA expression profiling in acute myeloid and chronic lymphocytic leukaemias

1 reference

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28 July 2018

Recurring mutations found by sequencing an acute myeloid leukemia genome

1 reference

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MicroRNA-1 and MicroRNA-133 in spontaneous myocardial differentiation of mouse embryonic stem cells

1 reference

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28 July 2018

Prognostic importance of MN1 transcript levels, and biologic insights from MN1-associated gene and microRNA expression signatures in cytogenetically normal acute myeloid leukemia: a cancer and leukemia group B study

1 reference

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28 July 2018

Metabolic enzymes as oncogenes or tumor suppressors

1 reference

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IDH1 and IDH2 mutations in gliomas

1 reference

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28 July 2018

IDH1 mutations at residue p.R132 (IDH1(R132)) occur frequently in high-grade gliomas but not in other solid tumors

1 reference

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Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML.

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Myeloid cell differentiation arrest by miR-125b-1 in myelodysplastic syndrome and acute myeloid leukemia with the t(2;11)(p21;q23) translocation

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Prognostic significance of, and gene and microRNA expression signatures associated with, CEBPA mutations in cytogenetically normal acute myeloid leukemia with high-risk molecular features: a Cancer and Leukemia Group B Study

1 reference

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28 July 2018

Prognostic implications of gene mutations in acute myeloid leukemia with normal cytogenetics

1 reference

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Deregulation of signaling pathways in acute myeloid leukemia

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Central review of cytogenetics is necessary for cooperative group correlative and clinical studies of adult acute leukemia: the Cancer and Leukemia Group B experience

1 reference

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Mutation of the Wilms' tumor 1 gene is a poor prognostic factor associated with chemotherapy resistance in normal karyotype acute myeloid leukemia: the United Kingdom Medical Research Council Adult Leukaemia Working Party

1 reference

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Low-dose interleukin-2 immunotherapy does not improve outcome of patients age 60 years and older with acute myeloid leukemia in first complete remission: Cancer and Leukemia Group B Study 9720.

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Wilms' tumor 1 gene mutations independently predict poor outcome in adults with cytogenetically normal acute myeloid leukemia: a cancer and leukemia group B study

1 reference

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FLT3 D835/I836 mutations are associated with poor disease-free survival and a distinct gene-expression signature among younger adults with de novo cytogenetically normal acute myeloid leukemia lacking FLT3 internal tandem duplications

1 reference

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Acute myeloid leukemia and myelodysplastic syndromes in older patients

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Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: are we ready for a prognostically prioritized molecular classification?

1 reference

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MD1 expression regulates development of regulatory T cells

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Independent confirmation of a prognostic gene-expression signature in adult acute myeloid leukemia with a normal karyotype: a Cancer and Leukemia Group B study

1 reference

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Age and acute myeloid leukemia

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Low or absent SPARC expression in acute myeloid leukemia with MLL rearrangements is associated with sensitivity to growth inhibition by exogenous SPARC protein

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Overexpression of the ETS-related gene, ERG, predicts a worse outcome in acute myeloid leukemia with normal karyotype: a Cancer and Leukemia Group B study

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MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias

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CEBPA mutations in younger adults with acute myeloid leukemia and normal cytogenetics: prognostic relevance and analysis of cooperating mutations

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Absence of the wild-type allele predicts poor prognosis in adult de novo acute myeloid leukemia with normal cytogenetics and the internal tandem duplication of FLT3: a cancer and leukemia group B study.

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ERG expression is an independent prognostic factor and allows refined risk stratification in cytogenetically normal acute myeloid leukemia: a comprehensive analysis of ERG, MN1, and BAALC transcript levels using oligonucleotide microarrays

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Rearrangement of ALL1 (MLL) in acute myeloid leukemia with normal cytogenetics

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12 December 2020

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High Expression Levels of theETS-Related Gene,ERG, Predict Adverse Outcome and Improve Molecular Risk-Based Classification of Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study

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https://pubmed.ncbi.nlm.nih.gov/20368543

12 December 2020

based on heuristic

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Parallel phase I studies of daunorubicin given with cytarabine and etoposide with or without the multidrug resistance modulator PSC-833 in previously untreated patients 60 years of age or older with acute myeloid leukemia: results of cancer and leuk

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12 December 2020

based on heuristic

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Identifiers

10.1200/JCO.2009.27.3730

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

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