H3K27 trimethylation is an early epigenetic event of p16INK4a silencing for regaining tumorigenesis in fusion reprogrammed hepatoma cells (Q33897945)

29 July 2017

title

H3K27 trimethylation is an early epigenetic event of p16INK4a silencing for regaining tumorigenesis in fusion reprogrammed hepatoma cells (English)

1 reference

29 July 2017

main subject

hepatocellular carcinoma

1 reference

Jia-Yi Yao

1

1 reference

29 July 2017

Lei Zhang

2

1 reference

29 July 2017

Xin Zhang

3

1 reference

29 July 2017

Zhi-Ying He

4

1 reference

29 July 2017

Yue Ma

5

1 reference

29 July 2017

Li-Jian Hui

6

1 reference

29 July 2017

Xin Wang

7

1 reference

29 July 2017

Yi-Ping Hu

8

1 reference

29 July 2017

language of work or name

English

0 references

publication date

10 April 2010

1 reference

Journal of Biological Chemistry

29 July 2017

number of pages

10

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

29 July 2017

volume

285

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29 July 2017

issue

24

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29 July 2017

page(s)

18828-18837

1 reference

Human embryonic stem cell microenvironment suppresses the tumorigenic phenotype of aggressive cancer cells

29 July 2017

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5 July 2018

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5 July 2018

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5 July 2018

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Erasure of cellular memory by fusion with pluripotent cells

5 July 2018

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A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing

5 July 2018

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5 July 2018

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5 July 2018

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Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state

5 July 2018

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5 July 2018

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5 July 2018

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Nuclei of embryonic stem cells reprogram somatic cells

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Liver tumor development. c-Jun antagonizes the proapoptotic activity of p53

5 July 2018

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5 July 2018

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Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements

5 July 2018

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5 July 2018

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In situ detection of the hypermethylation-induced inactivation of the p16 gene as an early event in oncogenesis

5 July 2018

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Progressive region-specific de novo methylation of the p16 CpG island in primary human mammary epithelial cell strains during escape from M(0) growth arrest

5 July 2018

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In vitro and in vivo study of pluripotency in intraspecific hybrid cells obtained by fusion of murine embryonic stem cells with splenocytes

5 July 2018

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Embryonic germ cells induce epigenetic reprogramming of somatic nucleus in hybrid cells

5 July 2018

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5 July 2018

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Inactivation of p16INK4 in hepatocellular carcinoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881805

Infrequent alterations of the p16INK4A gene in liver cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881805

Muscle cell components dictate hepatocyte gene expression and the distribution of the Golgi apparatus in heterokaryons

5 July 2018

1 reference

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Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes

5 July 2018

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Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

21 January 2018

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Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice

21 January 2018

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Nuclear reprogramming of somatic cells by in vitro hybridization with ES cells.

21 January 2018

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Comparison of neurosphere cells with cumulus cells after fusion with embryonic stem cells: reprogramming potential.

21 January 2018

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21 January 2018

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Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene.

21 January 2018

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Nanog promotes transfer of pluripotency after cell fusion.

21 January 2018

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Mouse embryos cloned from brain tumors

21 January 2018

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Methylation of p16(INK4a) promoters occurs in vivo in histologically normal human mammary epithelia.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881805

Mutational study of p16CDKN2/MTS1/INK4A and p57KIP2 genes in hepatocellular carcinoma

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20382980

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

p16(INK4) is inactivated by extensive CpG methylation in human hepatocellular carcinoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20382980

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M109.077974

1 reference

29 July 2017

1 reference

29 July 2017

1 reference