The muscarinic M(5) receptor: a silent or emerging subtype? (Q33898782)

29 July 2017

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title

The muscarinic M(5) receptor: a silent or emerging subtype? (English)

1 reference

29 July 2017

R M Eglen

1

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29 July 2017

S R Nahorski

series ordinal

2

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29 July 2017

language of work or name

English

0 references

publication date

1 May 2000

1 reference

British Journal of Pharmacology

29 July 2017

published in

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29 July 2017

volume

130

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29 July 2017

issue

1

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29 July 2017

page(s)

13-21

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Characterization of the muscarinic receptor in isolated uterus of sham operated and ovariectomized rats

29 July 2017

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5 July 2018

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5 July 2018

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5 July 2018

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The second intracellular loop of the m5 muscarinic receptor is the switch which enables G-protein coupling

5 July 2018

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Identification of a ligand-dependent switch within a muscarinic receptor

5 July 2018

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Pharmacological characterization of muscarinic receptors in rabbit isolated iris sphincter muscle and urinary bladder smooth muscle

5 July 2018

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5 July 2018

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Expression and localization of muscarinic receptors in P19-derived neurons

5 July 2018

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Structure/function relationships of a G-protein coupling pocket formed by the third intracellular loop of the m5 muscarinic receptor

5 July 2018

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Phosphorylation of phospholipase C-coupled receptors

5 July 2018

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Activation of the G protein Gq/11 through tyrosine phosphorylation of the alpha subunit

5 July 2018

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G-protein-coupled receptors: molecular mechanisms involved in receptor activation and selectivity of G-protein recognition

5 July 2018

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The M5 (m5) receptor subtype: fact or fiction?

5 July 2018

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Discovery & development of selective M3 antagonists for clinical use.

5 July 2018

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Functional role of M2 and M3 muscarinic receptors in the urinary bladder of rats in vitro and in vivo

5 July 2018

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Elementary and global aspects of calcium signalling

5 July 2018

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Muscarinic receptor subtypes and smooth muscle function

5 July 2018

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Functional properties of muscarinic receptor subtypes Hm1, Hm3 and Hm5 expressed in Sf9 cells using the baculovirus expression system.

5 July 2018

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Pharmacology of muscarinic acetylcholine receptor subtypes (m1-m5): high throughput assays in mammalian cells

5 July 2018

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The classification of seven transmembrane receptors in recombinant expression systems

5 July 2018

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Induction of muscarinic receptor subtypes in monocytic/macrophagic cells differentiated from EoL-1 cells

5 July 2018

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Diversity and selectivity of receptor-G protein interaction

5 July 2018

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Identification and molecular characterization of a m5 muscarinic receptor in A2058 human melanoma cells. Coupling to inhibition of adenylyl cyclase and stimulation of phospholipase A2

5 July 2018

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Muscarinic m1 receptor-stimulated adenylate cyclase activity in Chinese hamster ovary cells is mediated by Gs alpha and is not a consequence of phosphoinositidase C activation

5 July 2018

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Characterization of muscarinic agonists in recombinant cell lines

5 July 2018

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Intramolecular interactions in muscarinic acetylcholine receptors studied with chimeric m2/m5 receptors

5 July 2018

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Transfected muscarinic acetylcholine receptors selectively couple to Gi-type G proteins and Gq/11.

5 July 2018

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Muscarinic cholinergic receptor subtypes in rat sublingual glands

5 July 2018

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Cholinergic deafferentation of dorsal hippocampus by fimbria-fornix lesioning differentially regulates subtypes (m1-m5) of muscarinic receptors

5 July 2018

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Membrane organization in G-protein mechanisms.

5 July 2018

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Structure-function of muscarinic receptor coupling to G proteins. Random saturation mutagenesis identifies a critical determinant of receptor affinity for G proteins

5 July 2018

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Muscarinic acetylcholine receptors: signal transduction through multiple effectors.

5 July 2018

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Application of transfected cell lines in studies of functional receptor subtype selectivity of muscarinic agonists

5 July 2018

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Human muscarinic receptors expressed in A9L and CHO cells: activation by full and partial agonists

5 July 2018

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Oxybutynin. A review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic use in detrusor instability.

5 July 2018

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Muscarinic receptors--characterization, coupling and function

5 July 2018

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Receptor binding profiles of some selective muscarinic antagonists

5 July 2018

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Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes

5 July 2018

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Antagonist binding properties of five cloned muscarinic receptors expressed in CHO-K1 cells

5 July 2018

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Molecular cloning and expression of a fifth muscarinic acetylcholine receptor

5 July 2018

1 reference

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Cellular responses to stimulation of the M5 muscarinic acetylcholine receptor as seen in murine L cells

5 July 2018

1 reference

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Antagonist binding profiles of five cloned human muscarinic receptor subtypes

5 July 2018

1 reference

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Identification and localization of muscarinic acetylcholine receptor proteins in brain with subtype-specific antibodies

5 July 2018

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Functional responses of cloned muscarinic receptors expressed in CHO-K1 cells

5 July 2018

1 reference

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The ontogeny of m1–m5 muscarinic receptor subtypes in rat forebrain

5 July 2018

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Reconstitution of agonist-stimulated phosphatidylinositol 4,5-bisphosphate hydrolysis using purified m1 muscarinic receptor, Gq/11, and phospholipase C-beta 1

5 July 2018

1 reference

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Differences between natural and recombinant G protein-coupled receptor systems with varying receptor/G protein stoichiometry

5 July 2018

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Development of antisera selective for m4 and m5 muscarinic cholinergic receptors: distribution of m4 and m5 receptors in rat brain.

21 January 2018

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Differential regulation of molecular subtypes of muscarinic receptors in Alzheimer's disease.

29 October 2018

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m1-m5 muscarinic receptor distribution in rat CNS by RT-PCR and HPLC.

29 October 2018

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Pirenzepine distinguishes between different subclasses of muscarinic receptors

29 October 2018

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Muscarinic receptor-mediated tyrosine phosphorylation of phospholipase C-gamma. An alternative mechanism for cholinergic-induced phosphoinositide breakdown

29 October 2018

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12 December 2020

Characterization of muscarinic receptors in cultured human iris sphincter and ciliary smooth muscle cells

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12 December 2020

Muscarinic potentiation of excitatory amino acid-evoked dopamine release in mesencephalic cells: specificity for the NMDA response and role of intracellular messengers

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12 December 2020

Efficient coupling of m5 muscarinic acetylcholine receptors to activation of nitric oxide synthase

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12 December 2020

A tyrosine kinase signaling pathway, regulated by calcium entry and dissociated from tyrosine phosphorylation of phospholipase Cgamma-1, is involved in inositol phosphate production by activated G protein-coupled receptors in myometrium

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12 December 2020

Discrete activation of transduction pathways associated with acetylcholine m1 receptor by several muscarinic ligands

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12 December 2020

Differential coupling of m1, m2 and m3 muscarinic receptor subtypes to inositol 1,4,5-trisphosphate and adenosine 3',5'-cyclic monophosphate accumulation in Chinese hamster ovary cells

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12 December 2020

M2 muscarinic receptors on the iris sphincter muscle differ from those on iris noradrenergic nerves

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12 December 2020

Pharmacological basis for functional selectivity of partial muscarinic receptor agonists

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12 December 2020

Differential coupling of m1, m3, and m5 muscarinic receptors to activation of neuronal nitric oxide synthase

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12 December 2020

Variation in mRNA expression of alpha-adrenergic, neurokinin and muscarinic receptors amongst four arteries of the rat

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12 December 2020

Muscarinic receptor subtypes in human iris-ciliary body measured by immunoprecipitation

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12 December 2020

Pharmacology of muscarinic receptor subtypes constitutively activated by G proteins

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12 December 2020

Sequestration of human muscarinic acetylcholine receptor hm1-hm5 subtypes: effect of G protein-coupled receptor kinases GRK2, GRK4, GRK5 and GRK6

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12 December 2020

M1, M3 and M5 muscarinic receptors stimulate mitogen-activated protein kinase

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12 December 2020

Structural basis of the subtype selectivity of muscarinic antagonists: a study with chimeric m2/m5 muscarinic receptors

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12 December 2020

A muscarinic receptor different from the M1, M2, M3 and M4 subtypes mediates the contraction of the rabbit iris sphincter

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12 December 2020

Identifiers

DOI

10.1038/SJ.BJP.0703276

1 reference

29 July 2017

1 reference

29 July 2017

1 reference