Endogenous purinergic control of bladder activity via presynaptic P2X3 and P2X2/3 receptors in the spinal cord. (Q33898994)

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29 January 2020

title

Endogenous purinergic control of bladder activity via presynaptic P2X3 and P2X2/3 receptors in the spinal cord (English)

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29 January 2020

8

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author name string

Timothy K Y Kaan

1

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29 January 2020

Ping K Yip

2

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29 January 2020

John Grist

3

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29 January 2020

Joseph S Cefalu

4

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29 January 2020

Philip A Nunn

5

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29 January 2020

Anthony P D W Ford

6

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29 January 2020

Yu Zhong

7

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29 January 2020

language of work or name

English

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publication date

1 March 2010

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29 January 2020

published in

Journal of Neuroscience

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29 January 2020

volume

30

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issue

12

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29 January 2020

page(s)

4503-4507

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The ERK 1 and 2 pathway in the nervous system: from basic aspects to possible clinical applications in pain and visceral dysfunction

29 January 2020

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Evaluation of purinergic mechanism for the treatment of voiding dysfunction: a study in conscious spinal cord-injured rats

5 July 2018

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Investigation into the role of P2X(3)/P2X(2/3) receptors in neuropathic pain following chronic constriction injury in the rat: an electrophysiological study

5 July 2018

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Pharmacology of P2X channels

5 July 2018

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5 July 2018

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Purinoceptors as therapeutic targets for lower urinary tract dysfunction

5 July 2018

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P2X2 knockout mice and P2X2/P2X3 double knockout mice reveal a role for the P2X2 receptor subunit in mediating multiple sensory effects of ATP

5 July 2018

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A P2X receptor-mediated nociceptive afferent pathway to lamina I of the spinal cord

5 July 2018

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Investigation of the effects of P2 purinoceptor ligands on the micturition reflex in female urethane-anaesthetized rats

5 July 2018

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MAPK activation in nociceptive neurons and pain hypersensitivity

5 July 2018

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5 July 2018

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Effects of resiniferatoxin desensitization of capsaicin-sensitive afferents on detrusor over-activity induced by intravesical capsaicin, acetic acid or ATP in conscious rats

5 July 2018

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A-317491, a novel potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors, reduces chronic inflammatory and neuropathic pain in the rat.

5 July 2018

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Nerve growth factor induces P2X(3) expression in sensory neurons.

5 July 2018

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Agonists and antagonists acting at P2X receptors: selectivity profiles and functional implications

5 July 2018

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Urinary bladder hyporeflexia and reduced pain-related behaviour in P2X3-deficient mice

5 July 2018

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Evidence for the involvement of spinal endogenous ATP and P2X receptors in nociceptive responses caused by formalin and capsaicin in mice

5 July 2018

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Immunocytochemical localization of the vanilloid receptor 1 (VR1): relationship to neuropeptides, the P2X3 purinoceptor and IB4 binding sites

5 July 2018

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5 July 2018

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5 July 2018

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The use of the slowly degradable analog, alpha, beta-methylene ATP, to produce desensitisation of the P2-purinoceptor: effect on non-adrenergic, non-cholinergic responses of the guinea-pig urinary bladder

5 July 2018

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Identification and SAR of novel diaminopyrimidines. Part 1: The discovery of RO-4, a dual P2X(3)/P2X(2/3) antagonist for the treatment of pain

5 July 2018

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Identification and SAR of novel diaminopyrimidines. Part 2: The discovery of RO-51, a potent and selective, dual P2X(3)/P2X(2/3) antagonist for the treatment of pain

29 October 2018

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29 October 2018

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29 October 2018

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29 October 2018

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29 October 2018

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29 October 2018

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Increased spinal cord phosphorylation of extracellular signal-regulated kinases mediates micturition overactivity in rats with chronic bladder inflammation

29 October 2018

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29 October 2018

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The signaling components of sensory fiber transmission involved in the activation of ERK MAP kinase in the mouse dorsal horn

29 October 2018

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Distinct roles of P2X receptors in modulating glutamate release at different primary sensory synapses in rat spinal cord

29 October 2018

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Activation of central terminal vanilloid receptor-1 receptors and alpha beta-methylene-ATP-sensitive P2X receptors reveals a converged synaptic activity onto the deep dorsal horn neurons of the spinal cord.

29 October 2018

1 reference

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ATP P2X receptor-mediated enhancement of glutamate release and evoked EPSCs in dorsal horn neurons of the rat spinal cord.

29 October 2018

1 reference

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Inflammatory mediators potentiate ATP-gated channels through the P2X(3) subunit

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882023

Intravesical resiniferatoxin desensitizes rat bladder sensory fibres without causing intense noxious excitation. A c-fos study

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20335487

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A-317491, a selective P2X3/P2X2/3 receptor antagonist, reverses inflammatory mechanical hyperalgesia through action at peripheral receptors in rats

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20335487

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The activation of the ERK pathway contributes to the spinal c-fosexpression observed after noxious bladder stimulation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20335487

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1523/JNEUROSCI.6132-09.2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20335487%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

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29 January 2020

PubMed publication ID

20335487

1 reference