Visualizing inducible nitric-oxide synthase in living cells with a heme-binding fluorescent inhibitor (Q33900440)

29 July 2017

title

Visualizing inducible nitric-oxide synthase in living cells with a heme-binding fluorescent inhibitor (English)

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29 July 2017

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2

Mamta Chawla-Sarkar

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29 July 2017

Koustubh Panda

1

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29 July 2017

Cecile Santos

3

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29 July 2017

Thomas Koeck

4

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29 July 2017

Serpil C Erzurum

5

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29 July 2017

John F Parkinson

6

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29 July 2017

Dennis J Stuehr

7

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29 July 2017

language of work or name

English

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publication date

8 July 2005

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Proceedings of the National Academy of Sciences of the United States of America

29 July 2017

published in

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29 July 2017

volume

102

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29 July 2017

issue

29

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29 July 2017

page(s)

10117-10122

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Regulation of inducible nitric oxide synthase by rapid cellular turnover and cotranslational down-regulation by dimerization inhibitors

29 July 2017

cites work

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Allosteric inhibitors of inducible nitric oxide synthase dimerization discovered via combinatorial chemistry

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A novel, testis-specific mRNA transcript encoding an NH2-terminal truncated nitric-oxide synthase

5 July 2018

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Characterization of heme-deficient neuronal nitric-oxide synthase reveals a role for heme in subunit dimerization and binding of the amino acid substrate and tetrahydrobiopterin.

5 July 2018

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Heme iron reduction and catalysis by a nitric oxide synthase heterodimer containing one reductase and two oxygenase domains

5 July 2018

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Endothelial nitric-oxide synthase. Expression in Escherichia coli, spectroscopic characterization, and role of tetrahydrobiopterin in dimer formation.

5 July 2018

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Intracellular assembly of inducible NO synthase is limited by nitric oxide-mediated changes in heme insertion and availability

5 July 2018

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5 July 2018

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5 July 2018

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Oxidation of NG-hydroxy-L-arginine by nitric oxide synthase: evidence for the involvement of the heme in catalysis

5 July 2018

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5 July 2018

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5 July 2018

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Nitric oxide synthases: properties and catalytic mechanism

5 July 2018

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Nitric oxide synthase: Aspects concerning structure and catalysis

5 July 2018

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Isoforms of nitric oxide synthase. Properties, cellular distribution and expressional control.

5 July 2018

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5 July 2018

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Cloned, expressed rat cerebellar nitric oxide synthase contains stoichiometric amounts of heme, which binds carbon monoxide

5 July 2018

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Increased arginase II and decreased NO synthesis in endothelial cells of patients with pulmonary arterial hypertension

5 July 2018

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Exogenous nitric oxide activates the endothelial glucocorticoid receptor

29 October 2018

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Inducible nitric oxide synthase dimerization inhibitor prevents cardiovascular and renal morbidity in sheep with combined burn and smoke inhalation injury.

29 October 2018

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A selective inducible NOS dimerization inhibitor prevents systemic, cardiac, and pulmonary hemodynamic dysfunction in endotoxemic mice.

29 October 2018

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Distinct dimer interaction and regulation in nitric-oxide synthase types I, II, and III.

29 October 2018

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Mechanistic studies with potent and selective inducible nitric-oxide synthase dimerization inhibitors

29 October 2018

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Calmodulin activates intersubunit electron transfer in the neuronal nitric-oxide synthase dimer

29 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1177357

Haem insertion, dimerization and reactivation of haem-free rat neuronal nitric oxide synthase.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1177357

Calmodulin-dependent nitric-oxide synthase. Mechanism of inhibition by imidazole and phenylimidazoles

29 October 2018

1 reference

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Decreased Cu,Zn-SOD activity in asthmatic airway epithelium: correction by inhaled corticosteroid in vivo

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1177357

Synthesis of nitrite and nitrate in murine macrophage cell lines

29 October 2018

1 reference

12 December 2020

Macrophage nitric oxide synthase subunits. Purification, characterization, and role of prosthetic groups and substrate in regulating their association into a dimeric enzyme

1 reference

12 December 2020

Identification of nitric oxide synthase as a thiolate-ligated heme protein using magnetic circular dichroism spectroscopy. Comparison with cytochrome P-450-CAM and chloroperoxidase

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12 December 2020

Analysis of substrate-induced electronic, catalytic, and structural changes in inducible NO synthase

1 reference

12 December 2020

High-level expression of mouse inducible nitric oxide synthase in Escherichia coli requires coexpression with calmodulin

1 reference

12 December 2020

Comparative functioning of dihydro- and tetrahydropterins in supporting electron transfer, catalysis, and subunit dimerization in inducible nitric oxide synthase

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0408972102

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29 July 2017

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29 July 2017

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