The cis-regulatory effect of an Alzheimer's disease-associated poly-T locus on expression of TOMM40 and apolipoprotein E genes (Q33901364)

29 July 2017

title

The cis-regulatory effect of an Alzheimer's disease-associated poly-T locus on expression of TOMM40 and apolipoprotein E genes (English)

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29 July 2017

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Michael W Lutz

5

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James R Burke

object named as

James R Burke

9

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author name string

Colton Linnertz

1

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29 July 2017

Lauren Anderson

2

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29 July 2017

William Gottschalk

3

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Donna Crenshaw

4

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Jawara Allen

6

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Sunita Saith

7

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Mirta Mihovilovic

8

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Kathleen A Welsh-Bohmer

10

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Allen D Roses

11

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Ornit Chiba-Falek

12

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29 July 2017

publication date

15 January 2014

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29 July 2017

published in

Alzheimer's and Dementia

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29 July 2017

volume

10

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29 July 2017

issue

5

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29 July 2017

page(s)

541-551

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TOMM40 and APOE: Requirements for replication studies of association with age of disease onset and enrichment of a clinical trial.

29 July 2017

cites work

1 reference

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Using genetics to enable studies on the prevention of Alzheimer's disease

5 July 2018

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Comprehensive search for Alzheimer disease susceptibility loci in the APOE region

5 July 2018

1 reference

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A homopolymer polymorphism in the TOMM40 gene contributes to cognitive performance in aging

5 July 2018

1 reference

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Functional analysis of APOE locus genetic variation implicates regional enhancers in the regulation of both TOMM40 and APOE.

5 July 2018

1 reference

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Levels of cerebrospinal fluid neurofilament light protein in healthy elderly vary as a function of TOMM40 variants

5 July 2018

1 reference

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Mitochondria and cell bioenergetics: increasingly recognized components and a possible etiologic cause of Alzheimer's disease

5 July 2018

1 reference

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Association and expression analyses with single-nucleotide polymorphisms in TOMM40 in Alzheimer disease

5 July 2018

1 reference

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TOMM40 poly-T repeat lengths, age of onset and psychosis risk in Alzheimer disease.

5 July 2018

1 reference

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Cerebrospinal fluid cortisol concentrations in healthy elderly are affected by both APOE and TOMM40 variants

5 July 2018

1 reference

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The effect of TOMM40 poly-T length on gray matter volume and cognition in middle-aged persons with APOE ε3/ε3 genotype

5 July 2018

1 reference

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Association of ApoE and LRP mRNA levels with dementia and AD neuropathology

5 July 2018

1 reference

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Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage

5 July 2018

1 reference

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The Alzheimer's disease mitochondrial cascade hypothesis

5 July 2018

1 reference

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Genetic variation at a single locus and age of onset for Alzheimer's disease.

5 July 2018

1 reference

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A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease

5 July 2018

1 reference

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Genetic regulation of alpha-synuclein mRNA expression in various human brain tissues

5 July 2018

1 reference

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Mitochondrial trafficking of APP and alpha synuclein: Relevance to mitochondrial dysfunction in Alzheimer's and Parkinson's diseases

5 July 2018

1 reference

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Poly(dA:dT) tracts: major determinants of nucleosome organization

5 July 2018

1 reference

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The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae

5 July 2018

1 reference

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Expression of APP pathway mRNAs and proteins in Alzheimer's disease

5 July 2018

1 reference

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Conserved roles of Sam50 and metaxins in VDAC biogenesis

5 July 2018

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Gene expression profiling in single cells from the pancreatic islets of Langerhans reveals lognormal distribution of mRNA levels

5 July 2018

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The law of mass action applied to neurodegenerative disease: a hypothesis concerning the etiology and pathogenesis of complex diseases

5 July 2018

1 reference

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Poly(dA-dT) promoter elements increase the equilibrium accessibility of nucleosomal DNA target sites

5 July 2018

1 reference

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Biochemical studies of poly-T variants in the Alzheimer's disease associated TOMM40 gene.

5 July 2018

1 reference

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Downregulation of TOMM40 expression in the blood of Alzheimer disease subjects compared with matched controls

29 October 2018

1 reference

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TOMM40 rs10524523 polymorphism's role in late-onset Alzheimer's disease and in longevity.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098029

TaqMan systems for genotyping of disease-related polymorphisms present in the gene encoding apolipoprotein E.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098029

Increased apolipoprotein E mRNA in the hippocampus in Alzheimer disease and in rats after entorhinal cortex lesioning

29 October 2018

1 reference

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10.1016/J.JALZ.2013.08.280

29 October 2018

Identifiers

DOI

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29 July 2017

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29 July 2017

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