Interleukin-11 therapy selectively downregulates type I cytokine proinflammatory pathways in psoriasis lesions (Q33902313)

29 July 2017

Interleukin-11 therapy selectively downregulates type I cytokine proinflammatory pathways in psoriasis lesions (English)

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29 July 2017

W L Trepicchio

1

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29 July 2017

M Ozawa

2

1 reference

29 July 2017

I B Walters

3

1 reference

29 July 2017

T Kikuchi

4

1 reference

29 July 2017

P Gilleaudeau

5

1 reference

29 July 2017

J L Bliss

6

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29 July 2017

U Schwertschlag

7

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29 July 2017

A J Dorner

8

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29 July 2017

J G Krueger

9

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29 July 2017

language of work or name

English

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publication date

1 December 1999

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Journal of Clinical Investigation

29 July 2017

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29 July 2017

104

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29 July 2017

11

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29 July 2017

1527-1537

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409858

29 July 2017

1 reference

Recombinant human interleukin-11 does not affect functions of purified human neutrophils in vitro

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409858

Interleukin-11 promotes T cell polarization and prevents acute graft-versus-host disease after allogeneic bone marrow transplantation.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409858

IL-10 is a key cytokine in psoriasis. Proof of principle by IL-10 therapy: a new therapeutic approach

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409858

Regulation of the inflammatory response in animal models of multiple sclerosis by interleukin-12.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409858

Jaks and Stats in cytokine signaling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409858

Early events controlling T-helper cell differentiation: the role of the IL-12 receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409858

Langerhans cells may trigger the psoriatic disease process via production of nitric oxide

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409858

STATs and gene regulation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409858

Interleukin-11 inhibits macrophage interleukin-12 production

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409858

Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409858

A proinflammatory activity of interleukin 8 in human skin: expression of the inducible nitric oxide synthase in psoriatic lesions and cultured keratinocytes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409858

Real time quantitative PCR

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409858

Dermal injection of immunocytes induces psoriasis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409858

IL-11 enhances survival and decreases TNF production after radiation-induced thoracic injury.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409858

Inflammation, immunoregulation, and inducible nitric oxide synthase.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409858

Antibodies to interleukin 12 abrogate established experimental colitis in mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409858

Keratins (Kl6 and Kl7) as markers of keratinocyte hyperproliferation in psoriasis in vivo and in vitro

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409858

Adhesion of T lymphoblasts to epidermal keratinocytes is regulated by interferon gamma and is mediated by intercellular adhesion molecule 1 (ICAM-1).

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409858

Interleukin 6 is expressed in high levels in psoriatic skin and stimulates proliferation of cultured human keratinocytes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409858

Immune-associated surface markers of human keratinocytes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409858

Severe Psoriasis – Oral Therapy with a New Retinoid

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409858

The majority of epidermal T cells in Psoriasis vulgaris lesions can produce type 1 cytokines, interferon-gamma, interleukin-2, and tumor necrosis factor-alpha, defining TC1 (cytotoxic T lymphocyte) and TH1 effector populations: a type 1 differentiat

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409858

The regulation of IL-12: its role in infectious, autoimmune, and allergic diseases.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409858

Quantification of immunosuppression by flow cytometric measurement of intracellular cytokine synthesis.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409858

Differential effects of detergents on keratinocyte gene expression.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409858

29 October 2018

Treatment of psoriasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409858

The Cytokine Network in Lesional and Lesion-Free Psoriatic Skin Is Characterized by a T-Helper Type 1 Cell-Mediated Response

29 October 2018

1 reference

12 December 2020

Upper Keratinocytes of Psoriatic Skin Lesions Express High Levels of NAP-1/IL-8 mRNA In Situ

1 reference

12 December 2020

Treatment of recalcitrant plaque psoriasis with a humanized non-depleting antibody to CD4

1 reference

12 December 2020

IL-11, a pleiotropic cytokine: exciting new effects of IL-11 on gastrointestinal mucosal biology

1 reference

12 December 2020

Quantification of cytokine mRNA expression by RT PCR in samples of previously frozen blood

1 reference

12 December 2020

Studies of the effect of cyclosporine in psoriasis in vivo: combined effects on activated T lymphocytes and epidermal regenerative maturation

1 reference

12 December 2020

Narrowband UV-B produces superior clinical and histopathological resolution of moderate-to-severe psoriasis in patients compared with broadband UV-B

1 reference

12 December 2020

T lymphocytes in skin lesions of psoriasis and mycosis fungoides express B7-1: a ligand for CD28

1 reference

12 December 2020

IL-11 regulates macrophage effector function through the inhibition of nuclear factor-kappaB

1 reference

12 December 2020

Recombinant human interleukin-11 in experimental Pseudomonas aeruginosa sepsis in immunocompromised animals

1 reference

12 December 2020

Molecular effects of recombinant human interleukin-11 in the HLA-B27 rat model of inflammatory bowel disease

1 reference

12 December 2020

lnterleukin-8 Induces HLA-DR Expression on Cultured Human Keratinocytes via Specific Receptors

1 reference

12 December 2020

Recombinant human IL-11 attenuates the inflammatory response through down-regulation of proinflammatory cytokine release and nitric oxide production

1 reference

12 December 2020

Elevated tumour necrosis factor-alpha (TNF-alpha) biological activity in psoriatic skin lesions

1 reference

12 December 2020

Expression of interleukin-12 is increased in psoriatic skin

1 reference

12 December 2020

Response of psoriasis to a lymphocyte-selective toxin (DAB389IL-2) suggests a primary immune, but not keratinocyte, pathogenic basis

1 reference

12 December 2020

Epidermal keratinocyte expression of inducible nitric oxide synthase in skin lesions of psoriasis vulgaris

1 reference

12 December 2020

Increased expression of epidermal IL-8 receptor in psoriasis. Down-regulation by FK-506 in vitro

1 reference

12 December 2020

IL-8/IL-8 receptor expression in psoriasis and the response to systemic tacrolimus (FK506) therapy

1 reference

12 December 2020

Autocrine and paracrine regulation of human T cell IL-10 production

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI6910

1 reference

29 July 2017

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29 July 2017

1 reference