Altered responsiveness to chemokines due to targeted disruption of SHIP. (Q33903127)

29 July 2017

title

Altered responsiveness to chemokines due to targeted disruption of SHIP. (English)

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29 July 2017

8

H E Broxmeyer

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29 July 2017

C H Kim

1

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29 July 2017

G Hangoc

2

1 reference

29 July 2017

S Cooper

3

1 reference

29 July 2017

C D Helgason

4

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29 July 2017

S Yew

5

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29 July 2017

R K Humphries

6

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29 July 2017

G Krystal

7

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29 July 2017

language of work or name

English

0 references

publication date

1 December 1999

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Journal of Clinical Investigation

29 July 2017

published in

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29 July 2017

volume

104

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29 July 2017

issue

12

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29 July 2017

page(s)

1751-1759

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Abnormal chemokine-induced responses of immature and mature hematopoietic cells from motheaten mice implicate the protein tyrosine phosphatase SHP-1 in chemokine responses

29 July 2017

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5 July 2018

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5 July 2018

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The inositol phosphatase SHIP inhibits Akt/PKB activation in B cells

5 July 2018

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5 July 2018

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The CC chemokine monocyte chemotactic peptide-1 activates both the class I p85/p110 phosphatidylinositol 3-kinase and the class II PI3K-C2alpha.

5 July 2018

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The src homology 2-containing inositol phosphatase (SHIP) is the gatekeeper of mast cell degranulation

5 July 2018

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Macrophage-inflammatory protein-3 beta/EBI1-ligand chemokine/CK beta-11, a CC chemokine, is a chemoattractant with a specificity for macrophage progenitors among myeloid progenitor cells

5 July 2018

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The alpha-chemokine, stromal cell-derived factor-1alpha, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathways

5 July 2018

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5 July 2018

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Targeted disruption of SHIP leads to hemopoietic perturbations, lung pathology, and a shortened life span

5 July 2018

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The chemokine receptor CXCR-4 is expressed on CD34+ hematopoietic progenitors and leukemic cells and mediates transendothelial migration induced by stromal cell-derived factor-1.

5 July 2018

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SHIP modulates immune receptor responses by regulating membrane association of Btk.

5 July 2018

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Phosphatidylinositol-3,4,5-trisphosphate (PtdIns-3,4,5-P3)/Tec kinase-dependent calcium signaling pathway: a target for SHIP-mediated inhibitory signals

5 July 2018

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CK beta-11/macrophage inflammatory protein-3 beta/EBI1-ligand chemokine is an efficacious chemoattractant for T and B cells

5 July 2018

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The phosphatidylinositol polyphosphate 5-phosphatase SHIP and the protein tyrosine phosphatase SHP-2 form a complex in hematopoietic cells which can be regulated by BCR/ABL and growth factors

5 July 2018

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Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice

5 July 2018

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Two murine homologues of the human chemokine receptor CXCR4 mediating stromal cell-derived factor 1alpha activation of Gi2 are differentially expressed in vivo

5 July 2018

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Deletion of SHIP or SHP-1 reveals two distinct pathways for inhibitory signaling

5 July 2018

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5 July 2018

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Interleukin-3 induces the association of the inositol 5-phosphatase SHIP with SHP2

5 July 2018

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Interleukin 8-stimulated phosphatidylinositol-3-kinase activity regulates the migration of human neutrophils independent of extracellular signal-regulated kinase and p38 mitogen-activated protein kinases

5 July 2018

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The Src homology 2 (SH2) domain of SH2-containing inositol phosphatase (SHIP) is essential for tyrosine phosphorylation of SHIP, its association with Shc, and its induction of apoptosis

5 July 2018

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A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)

5 July 2018

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5 July 2018

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5 July 2018

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The inositol 5'-phosphatase SHIP binds to immunoreceptor signaling motifs and responds to high affinity IgE receptor aggregation

5 July 2018

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5 July 2018

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5 July 2018

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The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1

5 July 2018

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The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry

5 July 2018

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Multiple forms of an inositol polyphosphate 5-phosphatase form signaling complexes with Shc and Grb2

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409879

p150Ship, a signal transduction molecule with inositol polyphosphate-5-phosphatase activity

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409879

The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphatase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409879

The role of CXC chemokines as regulators of angiogenesis

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409879

Polymerization of murine macrophage inflammatory protein 1 alpha inactivates its myelosuppressive effects in vitro: the active form is a monomer

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409879

Unresponsiveness of primitive chronic myeloid leukemia cells to macrophage inflammatory protein 1 alpha, an inhibitor of primitive normal hematopoietic cells

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409879

RANTES-activated human T lymphocytes. A role for phosphoinositide 3-kinase

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409879

Human chemokines: enhancement of specific activity and effects in vitro on normal and leukemic progenitors and a factor-dependent cell line and in vivo in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409879

Chemotactic peptide modulation of actin assembly and locomotion in neutrophils

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409879

Chemokines: signal lamps for trafficking of T and B cells for development and effector function.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409879

Targeted disruption of SHIP leads to Steel factor-induced degranulation of mast cells.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409879

Differential chemotactic behavior of developing T cells in response to thymic chemokines

29 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409879

SLC/exodus2/6Ckine/TCA4 induces chemotaxis of hematopoietic progenitor cells: differential activity of ligands of CCR7, CXCR3, or CXCR4 in chemotaxis vs. suppression of progenitor proliferation

29 October 2018

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12 December 2020

The negative signaling molecule SH2 domain-containing inositol-polyphosphate 5-phosphatase (SHIP) binds to the tyrosine-phosphorylated beta subunit of the high affinity IgE receptor

1 reference

12 December 2020

In vitro behavior of hematopoietic progenitor cells under the influence of chemoattractants: stromal cell-derived factor-1, steel factor, and the bone marrow environment

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12 December 2020

Enhancing and suppressing effects of recombinant murine macrophage inflammatory proteins on colony formation in vitro by bone marrow myeloid progenitor cells

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12 December 2020

Identifiers

DOI

10.1172/JCI7310

1 reference

29 July 2017

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29 July 2017

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