Bone marrow CD34(+) cells and megakaryoblasts secrete beta-chemokines that block infection of hematopoietic cells by M-tropic R5 HIV. (Q33903275)

29 July 2017

title

Bone marrow CD34(+) cells and megakaryoblasts secrete beta-chemokines that block infection of hematopoietic cells by M-tropic R5 HIV. (English)

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29 July 2017

8

M Z Ratajczak

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29 July 2017

M Majka

1

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29 July 2017

T Rozmyslowicz

2

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29 July 2017

B Lee

3

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29 July 2017

S L Murphy

4

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29 July 2017

Z Pietrzkowski

5

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29 July 2017

G N Gaulton

6

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29 July 2017

L Silberstein

7

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29 July 2017

language of work or name

English

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publication date

1 December 1999

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Journal of Clinical Investigation

29 July 2017

published in

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29 July 2017

volume

104

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29 July 2017

issue

12

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29 July 2017

page(s)

1739-1749

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Binding of stromal derived factor-1alpha (SDF-1alpha) to CXCR4 chemokine receptor in normal human megakaryoblasts but not in platelets induces phosphorylation of mitogen-activated protein kinase p42/44 (MAPK), ELK-1 transcription factor and serine/t

29 July 2017

cites work

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Fusion of monocytes and macrophages with HIV-1 correlates with biochemical properties of CXCR4 and CCR5.

5 July 2018

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Megakaryocyte precursors, megakaryocytes and platelets express the HIV co-receptor CXCR4 on their surface: determination of response to stromal-derived factor-1 by megakaryocytes and platelets

5 July 2018

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5 July 2018

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Natural killer cells from HIV-1+ patients produce C-C chemokines and inhibit HIV-1 infection.

5 July 2018

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Peripheral blood-derived CD34+ progenitor cells: CXC chemokine receptor 4 and CC chemokine receptor 5 expression and infection by HIV.

5 July 2018

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Stromal cell-derived factor-1 alpha and stem cell factor/kit ligand share signaling pathways in hemopoietic progenitors: a potential mechanism for cooperative induction of chemotaxis.

5 July 2018

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5 July 2018

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Natural killer cells from human immunodeficiency virus (HIV)-infected individuals are an important source of CC-chemokines and suppress HIV-1 entry and replication in vitro

5 July 2018

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The chemokine receptor CXCR-4 is expressed on CD34+ hematopoietic progenitors and leukemic cells and mediates transendothelial migration induced by stromal cell-derived factor-1.

5 July 2018

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Chemokines and HIV-1 second receptors: the therapeutic connection

5 July 2018

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An intricate Web: chemokine receptors, HIV-1 and hematopoiesis

5 July 2018

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Beta-chemokines are released from HIV-1-specific cytolytic T-cell granules complexed to proteoglycans

5 July 2018

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5 July 2018

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The pathways connecting G protein-coupled receptors to the nucleus through divergent mitogen-activated protein kinase cascades

5 July 2018

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In vitro and in vivo evidence that ex vivo cytokine priming of donor marrow cells may ameliorate posttransplant thrombocytopenia.

5 July 2018

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5 July 2018

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Indicator cell lines for detection of primary strains of human and simian immunodeficiency viruses

5 July 2018

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Molecular and functional characterization of two novel human C-C chemokines as inhibitors of two distinct classes of myeloid progenitors

5 July 2018

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The chemokine SDF-1 is a chemoattractant for human CD34+ hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34+ progenitors to peripheral blood.

5 July 2018

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CD8+ T-cell-derived soluble factor(s), but not beta-chemokines RANTES, MIP-1 alpha, and MIP-1 beta, suppress HIV-1 replication in monocyte/macrophages

5 July 2018

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5 July 2018

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Polymerization of murine macrophage inflammatory protein 1 alpha inactivates its myelosuppressive effects in vitro: the active form is a monomer

5 July 2018

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Release from quiescence of CD34+ CD38- human umbilical cord blood cells reveals their potentiality to engraft adults

5 July 2018

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Requirement of MIP-1 alpha for an inflammatory response to viral infection.

5 July 2018

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Tyrosine sulfation of the amino terminus of CCR5 facilitates HIV-1 entry

5 July 2018

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Coreceptor/chemokine receptor expression on human hematopoietic cells: biological implications for human immunodeficiency virus-type 1 infection.

29 October 2018

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CD34+, kit+, rhodamine123(low) phenotype identifies a marrow cell population highly enriched for human hematopoietic stem cells.

29 October 2018

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Ex vivo culture of CD34+/Lin-/DR- cells in stroma-derived soluble factors, interleukin-3, and macrophage inflammatory protein-1alpha maintains not only myeloid but also lymphoid progenitors in a novel switch culture assay.

29 October 2018

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An improved serum free system for cloning human "pure" erythroid colonies. The role of different growth factors and cytokines on BFU-E formation by the bone marrow and cord blood CD34+ cells.

29 October 2018

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Inhibition of immature erythroid progenitor cell proliferation by macrophage inflammatory protein-1alpha by interacting mainly with a C-C chemokine receptor, CCR1

29 October 2018

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12 December 2020

MCP-1, not MIP-1alpha, is the endogenous chemokine that cooperates with TGF-beta to inhibit the cycling of primitive normal but not leukemic (CML) progenitors in long-term human marrow cultures

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12 December 2020

Interferon-gamma upregulates CCR5 expression in cord and adult blood mononuclear phagocytes

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12 December 2020

Comparative analysis of the human macrophage inflammatory protein family of cytokines (chemokines) on proliferation of human myeloid progenitor cells. Interacting effects involving suppression, synergistic suppression, and blocking of suppression

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12 December 2020

Expression of interleukin-1 beta gene in candidate human hematopoietic stem cells

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12 December 2020

Expression and physiologic significance of Kit ligand and stem cell tyrosine kinase-1 receptor ligand in normal human CD34+, c-Kit+ marrow cells

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12 December 2020

Cytokine and chemokine production by CD34+ haemopoietic progenitor cells: detection in single cells

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12 December 2020

The role of insulin (INS) and insulin-like growth factor-I (IGF-I) in regulating human erythropoiesis. Studies in vitro under serum-free conditions – comparison to other cytokines and growth factors

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12 December 2020

Identifiers

DOI

10.1172/JCI7779

1 reference

29 July 2017

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29 July 2017

1 reference