Cytotoxic potential of lung CD8(+) T cells increases with chronic obstructive pulmonary disease severity and with in vitro stimulation by IL-18 or IL-15. (Q33903742)

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English	Cytotoxic potential of lung CD8(+) T cells increases with chronic obstructive pulmonary disease severity and with in vitro stimulation by IL-18 or IL-15.	scientific article

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scholarly article

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Europe PubMed Central

29 July 2017

Cytotoxic potential of lung CD8(+) T cells increases with chronic obstructive pulmonary disease severity and with in vitro stimulation by IL-18 or IL-15. (English)

1 reference

Europe PubMed Central

29 July 2017

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chronic obstructive pulmonary disease

1 reference

based on heuristic

inferred from title

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Susan Murray

4

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Jeffrey L. Curtis

object named as

Jeffrey L Curtis

15

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Fernando J Martinez

3

object named as

Fernando J Martinez

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Europe PubMed Central

29 July 2017

2

object named as

MeiLan K Han

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Europe PubMed Central

29 July 2017

Christine M Freeman

1

object named as

Christine M Freeman

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Europe PubMed Central

29 July 2017

Stephen W Chensue

6

object named as

Stephen W Chensue

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Europe PubMed Central

29 July 2017

Joanne Sonstein

8

object named as

Joanne Sonstein

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Europe PubMed Central

29 July 2017

9

object named as

Jill C Todt

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Europe PubMed Central

29 July 2017

10

object named as

Theresa M Ames

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Europe PubMed Central

29 July 2017

Douglas Arenberg

11

object named as

Douglas A Arenberg

1 reference

Europe PubMed Central

29 July 2017

Catherine A Meldrum

12

object named as

Catherine A Meldrum

1 reference

Europe PubMed Central

29 July 2017

13

object named as

Christi Getty

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Europe PubMed Central

29 July 2017

14

object named as

Lisa McCloskey

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Europe PubMed Central

29 July 2017

author name string

Lyrica X Liu

5

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29 July 2017

Timothy J Polak

7

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29 July 2017

language of work or name

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publication date

28 April 2010

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29 July 2017

Journal of Immunology

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29 July 2017

184

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29 July 2017

11

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29 July 2017

6504-6513

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Europe PubMed Central

29 July 2017

Lung dendritic cell expression of maturation molecules increases with worsening chronic obstructive pulmonary disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

5 July 2018

Altered effector function of peripheral cytotoxic cells in COPD.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

5 July 2018

Sustained CTL activation by murine pulmonary epithelial cells promotes the development of COPD-like disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

5 July 2018

Respiratory syncytial virus persistence in chronic obstructive pulmonary disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

5 July 2018

The cytolytic enzymes granyzme A, granzyme B, and perforin: expression patterns, cell distribution, and their relationship to cell maturity and bright CD57 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

5 July 2018

IL-7 and IL-15 differentially regulate CD8+ T-cell subsets during contraction of the immune response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

5 July 2018

Cigarette smoke selectively enhances viral PAMP- and virus-induced pulmonary innate immune and remodeling responses in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

5 July 2018

An IFN-gamma-IL-18 signaling loop accelerates memory CD8+ T cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

5 July 2018

Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

5 July 2018

Memory CD8+ T cells protect dendritic cells from CTL killing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

5 July 2018

The immunopathogenesis of chronic obstructive pulmonary disease: insights from recent research

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

5 July 2018

Perforin, granzyme B, and FasL expression by peripheral blood T lymphocytes in emphysema

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

5 July 2018

Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

5 July 2018

CC chemokine receptor 5 and CXC chemokine receptor 6 expression by lung CD8+ cells correlates with chronic obstructive pulmonary disease severity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

5 July 2018

Antielastin autoimmunity in tobacco smoking-induced emphysema

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

5 July 2018

Human effector CD8+ T lymphocytes express TLR3 as a functional coreceptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

5 July 2018

Elevated MMP-12 protein levels in induced sputum from patients with COPD.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

5 July 2018

Selective accumulation of differentiated CD8+ T cells specific for respiratory viruses in the human lung.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

5 July 2018

Local and systemic inflammation in chronic obstructive pulmonary disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

5 July 2018

Role of viruses in exacerbations of chronic obstructive pulmonary disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

5 July 2018

An immune basis for lung parenchymal destruction in chronic obstructive pulmonary disease and emphysema

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

5 July 2018

Synthesis and secretion of interleukin-15 by freshly isolated human bronchial epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

5 July 2018

Activation, differentiation, and migration of naive virus-specific CD8+ T cells during pulmonary influenza virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

5 July 2018

The nature of small-airway obstruction in chronic obstructive pulmonary disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

5 July 2018

Bystander suppression of allergic airway inflammation by lung resident memory CD8+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

5 July 2018

Interleukin 18 acts on memory T helper cells type 1 to induce airway inflammation and hyperresponsiveness in a naive host mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

5 July 2018

IL-15 mimics T cell receptor crosslinking in the induction of cellular proliferation, gene expression, and cytotoxicity in CD8+ memory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

5 July 2018

Interleukin-18 is a unique cytokine that stimulates both Th1 and Th2 responses depending on its cytokine milieu

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

5 July 2018

Interleukin-18 regulates both Th1 and Th2 responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

5 July 2018

Interferon gamma induction of pulmonary emphysema in the adult murine lung

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

5 July 2018

CD8+ve cells in the lungs of smokers with chronic obstructive pulmonary disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

5 July 2018

Molecular cloning, expression, and chromosomal localization of the human earliest lymphocyte activation antigen AIM/CD69, a new member of the C-type animal lectin superfamily of signal-transmitting receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

5 July 2018

Direct contact between T lymphocytes and monocytes is a major pathway for induction of metalloproteinase expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

5 July 2018

Cloning of a new cytokine that induces IFN-gamma production by T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

5 July 2018

Interleukin-18 production and pulmonary function in COPD.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

29 October 2018

Profound enhancement of the IL-12/IL-18 pathway of IFN-gamma secretion in human CD8+ memory T cell subsets via IL-15.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

29 October 2018

Pulmonary inflammation and emphysema: role of the cytokines IL-18 and IL-13.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

29 October 2018

Airway epithelial IL-15 transforms monocytes into dendritic cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

29 October 2018

IL-18 is induced and IL-18 receptor alpha plays a critical role in the pathogenesis of cigarette smoke-induced pulmonary emphysema and inflammation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

29 October 2018

Three memory subsets of human CD8+ T cells differently expressing three cytolytic effector molecules.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

29 October 2018

Mechanisms of autoimmune emphysema

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

29 October 2018

Trends in the leading causes of death in the United States, 1970-2002.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

29 October 2018

Direct stimulation of human T cells via TLR5 and TLR7/8: flagellin and R-848 up-regulate proliferation and IFN-gamma production by memory CD4+ T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

29 October 2018

Increase in macrophage elastase (MMP-12) in lungs from patients with chronic obstructive pulmonary disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

29 October 2018

Activation of virus-specific CD8+ T cells by lipopolysaccharide-induced IL-12 and IL-18.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

29 October 2018

IL-15 induces antigen-independent expansion and differentiation of human naive CD8+ T cells in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

29 October 2018

Apoptosis and emphysema: the missing link.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

29 October 2018

Long-term maintenance of virus-specific effector memory CD8+ T cells in the lung airways depends on proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

29 October 2018

Cytomegalovirus seropositivity drives the CD8 T cell repertoire toward greater clonality in healthy elderly individuals.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

29 October 2018

Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

29 October 2018

Interleukin 18 (IL-18) in synergy with IL-2 induces lethal lung injury in mice: a potential role for cytokines, chemokines, and natural killer cells in the pathogenesis of interstitial pneumonia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

29 October 2018

Long-term persistence and reactivation of T cell memory in the lung of mice infected with respiratory syncytial virus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

29 October 2018

Human lung tissue macrophages, but not alveolar macrophages, express matrix metalloproteinases after direct contact with activated T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

29 October 2018

Site and Nature of Airway Obstruction in Chronic Obstructive Lung Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

29 October 2018

Leu 23 induction as an early marker of functional CD3/T cell antigen receptor triggering. Requirement for receptor cross-linking, prolonged elevation of intracellular [Ca++] and stimulation of protein kinase C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

29 October 2018

Intracellular cytokine profile of T lymphocytes in patients with chronic obstructive pulmonary disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098931

10 December 2018

The CD69 receptor: a multipurpose cell-surface trigger for hematopoietic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammation in bronchial biopsies of subjects with chronic bronchitis: inverse relationship of CD8+ T lymphocytes with FEV1

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinase expression and production by alveolar macrophages in emphysema

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD8+ T-lymphocytes in peripheral airways of smokers with chronic obstructive pulmonary disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemoattraction of Human T Cells by IL-18

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Predominant TH1 cytokine pattern in peripheral blood from subjects with chronic obstructive pulmonary disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine production by bronchoalveolar lavage T lymphocytes in chronic obstructive pulmonary disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TCR-independent cytokine stimulation induces non-MHC-restricted T cell activity and is negatively regulated by HLA class I

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased airway granzyme b and perforin in current and ex-smoking COPD subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated Levels of IL-18 in Plasma and Skeletal Muscle in Chronic Obstructive Pulmonary Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection of CD8+ T cells from activation-induced cell death by IL-18

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Airway epithelium expresses interleukin-18

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human collagenase (matrix metalloproteinase-1) expression in the lungs of patients with emphysema

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lymphocyte population and apoptosis in the lungs of smokers and their relation to emphysema

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Perforin expression and cytotoxic activity of sputum CD8+ lymphocytes in patients with COPD

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.1000006

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

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