Prodrug-activating systems in suicide gene therapy. (Q33904264)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10791987%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

review article

1 reference

title

Prodrug-activating systems in suicide gene therapy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10791987%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

0 references

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10791987%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

author name string

I Niculescu-Duvaz

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10791987%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

language of work or name

English

0 references

publication date

1 May 2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10791987%20AND%20SRC:MED&resulttype=core&format=json

Journal of Clinical Investigation

6 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10791987%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

volume

105

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10791987%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10791987%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

page(s)

1161-1167

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10791987%20AND%20SRC:MED&resulttype=core&format=json

Immunomodulation of cancer: potential use of selectively replicating agents

6 November 2019

cites work

1 reference

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Gene delivery from replication-selective viruses: arming guided missiles in the war against cancer

5 July 2018

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Efficacy of a replication-competent adenovirus (ONYX-015) following intratumoral injection: intratumoral spread and distribution effects

5 July 2018

1 reference

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Self-immolative anthracycline prodrugs for suicide gene therapy

5 July 2018

1 reference

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Improving enzymes for cancer gene therapy

5 July 2018

1 reference

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The bystander effect in the HSVtk/ganciclovir system and its relationship to gap junctional communication

5 July 2018

1 reference

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Self-immolative nitrogen mustard prodrugs for suicide gene therapy.

5 July 2018

1 reference

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Superior cytotoxicity with ganciclovir compared with acyclovir and 1-beta-D-arabinofuranosylthymine in herpes simplex virus-thymidine kinase-expressing cells: a novel paradigm for cell killing.

5 July 2018

1 reference

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The design of selectively-activated anti-cancer prodrugs for use in antibody-directed and gene-directed enzyme-prodrug therapies

5 July 2018

1 reference

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Double suicide gene (cytosine deaminase and herpes simplex virus thymidine kinase) but not single gene transfer allows reliable elimination of tumor cells in vivo

5 July 2018

1 reference

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Gene-directed enzyme prodrug therapy: quantitative bystander cytotoxicity and DNA damage induced by CB1954 in cells expressing bacterial nitroreductase

5 July 2018

1 reference

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Potentiation of cytochrome P450/cyclophosphamide-based cancer gene therapy by coexpression of the P450 reductase gene

5 July 2018

1 reference

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Anti-tumor immunity is involved in the thymidine kinase-mediated killing of tumors induced by activated Ki-ras(G12V).

5 July 2018

1 reference

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Expression of the bacterial nitroreductase enzyme in mammalian cells renders them selectively sensitive to killing by the prodrug CB1954.

5 July 2018

1 reference

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Creation of drug-specific herpes simplex virus type 1 thymidine kinase mutants for gene therapy

5 July 2018

1 reference

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Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315452

Superiority of yeast over bacterial cytosine deaminase for enzyme/prodrug gene therapy in colon cancer xenografts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315452

Enhancement of the herpes simplex virus thymidine kinase/ganciclovir bystander effect and its antitumor efficacy in vivo by pharmacologic manipulation of gap junctions

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315452

Superior cytostatic activity of the ganciclovir elaidic acid ester due to the prolonged intracellular retention of ganciclovir anabolites in herpes simplex virus type 1 thymidine kinase gene-transfected tumor cells

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315452

Differential ganciclovir-mediated cytotoxicity and bystander killing in human colon carcinoma cell lines expressing herpes simplex virus thymidine kinase

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315452

Bystander tumoricidal effect and gap junctional communication in lung cancer cell lines.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315452

A cell surface tethered enzyme improves efficiency in gene-directed enzyme prodrug therapy

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315452

Combination suicide and cytokine gene therapy for hepatic metastases of colon carcinoma: sustained antitumor immunity prolongs animal survival.

29 October 2018

1 reference

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Gene-Directed Enzyme Prodrug Therapy

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315452

Gene-directed enzyme prodrug therapy with a mustard prodrug/carboxypeptidase G2 combination

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315452

In vivo analysis of the 'bystander effect': a cytokine cascade

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10791987

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Toward antibody-directed enzyme prodrug therapy with the T268G mutant of human carboxypeptidase A1 and novel in vivo stable prodrugs of methotrexate

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10791987

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Concomitant expression of E. coli cytosine deaminase and uracil phosphoribosyltransferase improves the cytotoxicity of 5-fluorocytosine

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10791987

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1172/JCI10001

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10791987%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10791987%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

PubMed publication ID

10791987

1 reference