The DNA-unwinding mechanism of the ring helicase of bacteriophage T7. (Q33904389)

29 July 2017

The DNA-unwinding mechanism of the ring helicase of bacteriophage T7. (English)

1 reference

29 July 2017

1 reference

Yong-Joo Jeong

1

1 reference

PubMed ID

15123793

29 July 2017

Mikhail K Levin

series ordinal

2

1 reference

PubMed ID

15123793

29 July 2017

Smita S Patel

series ordinal

3

1 reference

29 July 2017

3 May 2004

1 reference

Proceedings of the National Academy of Sciences of the United States of America

29 July 2017

1 reference

29 July 2017

101

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29 July 2017

19

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29 July 2017

7264-7269

1 reference

General Methods for Analysis of Sequential “n-step” Kinetic Mechanisms: Application to Single Turnover Kinetics of Helicase-Catalyzed DNA Unwinding

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409907

Mcm4,6,7 uses a "pump in ring" mechanism to unwind DNA by steric exclusion and actively translocate along a duplex.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409907

Structure of the replicative helicase of the oncoprotein SV40 large tumour antigen

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409907

The 2B domain of the Escherichia coli Rep protein is not required for DNA helicase activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409907

Pre-steady-state DNA unwinding by bacteriophage T4 Dda helicase reveals a monomeric molecular motor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409907

Hepatitis C virus NS3 and simian virus 40 T antigen helicases displace streptavidin from 5'-biotinylated oligonucleotides but not from 3'-biotinylated oligonucleotides: evidence for directional bias in translocation on single-stranded DNA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409907

A general model for nucleic acid helicases and their "coupling" within macromolecular machines

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409907

Processive translocation and DNA unwinding by individual RecBCD enzyme molecules

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409907

Structure and function of hexameric helicases.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409907

Uncoupling DNA translocation and helicase activity in PcrA: direct evidence for an active mechanism.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409907

Crystal structure of T7 gene 4 ring helicase indicates a mechanism for sequential hydrolysis of nucleotides

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409907

Crystal structure of the helicase domain from the replicative helicase-primase of bacteriophage T7

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409907

DNA helicases displace streptavidin from biotin-labeled oligonucleotides

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409907

Crystal structures of complexes of PcrA DNA helicase with a DNA substrate indicate an inchworm mechanism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409907

Kinetics of conformational fluctuations in DNA hairpin-loops

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409907

Coordinated leading and lagging strand DNA synthesis on a minicircular template.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409907

A hexameric helicase encircles one DNA strand and excludes the other during DNA unwinding

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409907

Mechanisms of helicase-catalyzed DNA unwinding

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409907

DNA is bound within the central hole to one or two of the six subunits of the T7 DNA helicase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409907

Stoichiometry and DNA unwinding by the bacteriophage T4 41:59 helicase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409907

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409907

Coupling of a replicative polymerase and helicase: a tau-DnaB interaction mediates rapid replication fork movement

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409907

Oligomeric structure of bacteriophage T7 DNA primase/helicase proteins.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409907

Interactions of bacteriophage T7 DNA primase/helicase protein with single-stranded and double-stranded DNAs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409907

DNA helicases: enzymes with essential roles in all aspects of DNA metabolism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409907

Bacteriophage T7 helicase/primase proteins form rings around single-stranded DNA that suggest a general structure for hexameric helicases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409907

The gene 4 protein of bacteriophage T7. Characterization of helicase activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409907

Interactions of the DNA polymerase and gene 4 protein of bacteriophage T7. Protein-protein and protein-DNA interactions involved in RNA-primed DNA synthesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409907

The contribution of DNA single-stranded order to the thermodynamics of duplex formation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409907

Energy flow considerations and thermal fluctuational opening of DNA base pairs at a replicating fork: unwinding consistent with observed replication rates

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409907

Large scale purification and biochemical characterization of T7 primase/helicase proteins. Evidence for homodimer and heterodimer formation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409907

DnaB drives DNA branch migration and dislodges proteins while encircling two DNA strands.

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400372101

Active disruption of an RNA-protein interaction by a DExH/D RNA helicase

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400372101

A motor that makes its own track: helicase unwinding of DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400372101

Kinetic measurement of the step size of DNA unwinding by Escherichia coli UvrD helicase

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400372101

T7 DNA helicase: a molecular motor that processively and unidirectionally translocates along single-stranded DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400372101

Asymmetric interactions of hexameric bacteriophage T7 DNA helicase with the 5'- and 3'-tails of the forked DNA substrate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400372101

Cooperative interactions of nucleotide ligands are linked to oligomerization and DNA binding in bacteriophage T7 gene 4 helicases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400372101

E. coli Rep oligomers are required to initiate DNA unwinding in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400372101

Demonstration of unidirectional single-stranded DNA translocation by PcrA helicase: measurement of step size and translocation speed

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400372101

The DExH protein NPH-II is a processive and directional motor for unwinding RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400372101

The 3′-tail of a forked-duplex sterically determines whether one or two DNA strands pass through the central channel of a replication-fork helicase 1 1Edited by M. Gottesman

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400372101

Escherichia coli rep helicase unwinds DNA by an active mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400372101

Studies of base pair kinetics by NMR measurement of proton exchange

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400372101

Substrate requirements for duplex DNA translocation by the eukaryal and archaeal minichromosome maintenance helicases

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400372101

Bacteriophage T7 DNA helicase binds dTTP, forms hexamers, and binds DNA in the absence of Mg2+. The presence of dTTP is sufficient for hexamer formation and DNA binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400372101

Complex of Escherichia coli primary replicative helicase DnaB protein with a replication fork: recognition and structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400372101

21 January 2018

Identifiers

DOI

10.1073/PNAS.0400372101

1 reference

29 July 2017

0 references

1 reference

29 July 2017

1 reference

PubMed ID

15123793