Lysine-specific demethylase 1 is a therapeutic target for fetal hemoglobin induction (Q33907537)

29 July 2017

Lysine-specific demethylase 1 is a therapeutic target for fetal hemoglobin induction (English)

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29 July 2017

Lihong Shi

1

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29 July 2017

Shuaiying Cui

series ordinal

2

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29 July 2017

James D Engel

series ordinal

3

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29 July 2017

Osamu Tanabe

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4

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29 July 2017

language of work or name

English

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publication date

17 February 2013

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29 July 2017

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29 July 2017

19

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3

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29 July 2017

291-294

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https://scigraph.springernature.com/pub.10.1038/nm.3101

29 July 2017

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cites work

Lysine-specific demethylase 1 restricts hematopoietic progenitor proliferation and is essential for terminal differentiation

1 reference

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Correction of sickle cell disease in adult mice by interference with fetal hemoglobin silencing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5512162

Nuclear receptors TR2 and TR4 recruit multiple epigenetic transcriptional corepressors that associate specifically with the embryonic β-type globin promoters in differentiated adult erythroid cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5512162

Transcriptional regulation of fetal to adult hemoglobin switching: new therapeutic opportunities

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5512162

siDNMT1 increases γ-globin expression in chemical inducer of dimerization (CID)-dependent mouse βYAC bone marrow cells and in baboon erythroid progenitor cell cultures

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5512162

Developmental and species-divergent globin switching are driven by BCL11A

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5512162

LSD1-mediated epigenetic modification is required for TAL1 function and hematopoiesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5512162

The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5512162

Fetal hemoglobin chemical inducers for treatment of hemoglobinopathies.

5 July 2018

1 reference

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Withdrawal from high-dose tranylcypromine

5 July 2018

1 reference

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Pomalidomide and lenalidomide regulate erythropoiesis and fetal hemoglobin production in human CD34+ cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5512162

A QTL influencing F cell production maps to a gene encoding a zinc-finger protein on chromosome 2p15.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5512162

Epigenetic regulation of hematopoietic differentiation by Gfi-1 and Gfi-1b is mediated by the cofactors CoREST and LSD1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5512162

Embryonic and fetal beta-globin gene repression by the orphan nuclear receptors, TR2 and TR4.

5 July 2018

1 reference

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Tranylcypromine: new perspectives on an "old" drug

5 July 2018

1 reference

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Histone H3 lysine 4 demethylation is a target of nonselective antidepressive medications

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5512162

Histone demethylation mediated by the nuclear amine oxidase homolog LSD1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5512162

Ex vivo generation of fully mature human red blood cells from hematopoietic stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5512162

Exploration, normalization, and summaries of high density oligonucleotide array probe level data

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5512162

An embryonic/fetal beta-type globin gene repressor contains a nuclear receptor TR2/TR4 heterodimer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5512162

A combination of hydroxyurea and isobutyramide to induce fetal hemoglobin in transgenic mice is more hematotoxic than the individual agents

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5512162

Pharmacokinetics of monoamine oxidase inhibitors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5512162

5 July 2018

Identifiers

DOI

10.1038/NM.3101

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29 July 2017

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29 July 2017

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