Imaging progesterone receptor in breast tumors: synthesis and receptor binding affinity of fluoroalkyl-substituted analogues of tanaproget. (Q33909035)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20355713%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

title

Imaging progesterone receptor in breast tumors: synthesis and receptor binding affinity of fluoroalkyl-substituted analogues of tanaproget (English)

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29 January 2020

1

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29 January 2020

author name string

Jae Hak Lee

2

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29 January 2020

Christopher G Mayne

3

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29 January 2020

Kathryn E Carlson

4

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29 January 2020

John A Katzenellenbogen

5

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29 January 2020

language of work or name

English

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publication date

1 April 2010

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Journal of Medicinal Chemistry

29 January 2020

published in

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29 January 2020

volume

53

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29 January 2020

issue

8

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29 January 2020

page(s)

3349-3360

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Tamoxifen: the drug that came in from the cold

29 January 2020

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Compound profiling using a panel of steroid hormone receptor cell-based assays

5 July 2018

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Evaluation of a bromine-76-labeled progestin 16alpha,17alpha-dioxolane for breast tumor imaging and radiotherapy: in vivo biodistribution and metabolic stability studies

5 July 2018

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A new generation of progesterone receptor modulators

5 July 2018

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5 July 2018

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5 July 2018

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Synthesis and structure-activity relationship of novel 6-aryl-1,4-dihydrobenzo[d][1,3]oxazine-2-thiones as progesterone receptor modulators leading to the potent and selective nonsteroidal progesterone receptor agonist tanaproget

5 July 2018

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Molecular and pharmacological properties of a potent and selective novel nonsteroidal progesterone receptor agonist tanaproget

5 July 2018

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Aromatase inhibitors: rationale and use in breast cancer

5 July 2018

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Characterization of a new class of selective nonsteroidal progesterone receptor agonists

5 July 2018

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Novel 6-aryl-1,4-dihydrobenzo[d]oxazine-2-thiones as potent, selective, and orally active nonsteroidal progesterone receptor agonists

5 July 2018

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Progesterone receptors--animal models and cell signalling in breast cancer. Diverse activation pathways for the progesterone receptor: possible implications for breast biology and cancer

5 July 2018

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Nonsteroidal progesterone receptor ligands with unprecedented receptor selectivity

5 July 2018

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Progesterone antagonists and progesterone receptor modulators in the treatment of breast cancer

5 July 2018

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5 July 2018

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Metabolism of a [18F]fluorine labeled progestin (21-[18F]fluoro-16 alpha-ethyl-19-norprogesterone) in humans: a clue for future investigations

5 July 2018

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The pharmacology and clinical uses of tamoxifen

5 July 2018

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Towards the mapping of the progesterone and androgen receptors

5 July 2018

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Fluorinated androgens and progestins: molecular probes for androgen and progesterone receptors with potential use in positron emission tomography.

5 July 2018

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Correspondence analysis applied to steroid receptor binding.

5 July 2018

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Endocrine treatment of breast cancer in women

5 July 2018

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Fluorine-substituted corticosteroids: synthesis and evaluation as potential receptor-based imaging agents for positron emission tomography of the brain

5 July 2018

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Ab initio fragment molecular orbital study of ligand binding to human progesterone receptor ligand-binding domain

5 July 2018

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Synthesis and biological evaluation of [18F]bicalutamide, 4-[76Br]bromobicalutamide, and 4-[76Br]bromo-thiobicalutamide as non-steroidal androgens for prostate cancer imaging.

29 October 2018

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29 October 2018

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Progesterone Receptor Status Significantly Improves Outcome Prediction Over Estrogen Receptor Status Alone for Adjuvant Endocrine Therapy in Two Large Breast Cancer Databases

29 October 2018

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The binding mode of progesterone to its receptor deduced from molecular dynamics simulations

29 October 2018

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Metabolic flare: indicator of hormone responsiveness in advanced breast cancer

29 October 2018

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29 October 2018

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Fluorine-18-labeled progestin ketals: synthesis and target tissue uptake selectivity of potential imaging agents for receptor-positive breast tumors.

29 October 2018

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Endocrine therapy for advanced carcinoma of the breast: relationship between the effect of tamoxifen upon concentrations of progesterone receptor and subsequent response to treatment

29 October 2018

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Increase of progesterone receptor by tamoxifen as a hormonal challenge test in breast cancer

10 December 2018

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12 December 2020

Induction of progesterone receptor with tamoxifen in human breast cancer with special reference to its behavior over time

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12 December 2020

Binding of steroids to the progestin and glucocorticoid receptors analyzed by correspondence analysis

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12 December 2020

Fluorine-18-labeled progestin 16 alpha, 17 alpha-dioxolanes: development of high-affinity ligands for the progesterone receptor with high in vivo target site selectivity

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12 December 2020

Positron emission tomography with 2-[18F]Fluoro-2-deoxy-D-glucose and 16alpha-[18F]fluoro-17beta-estradiol in breast cancer: correlation with estrogen receptor status and response to systemic therapy

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12 December 2020

Bromine- and iodine-substituted 16alpha,17alpha-dioxolane progestins for breast tumor imaging and radiotherapy: synthesis and receptor binding affinity

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12 December 2020

Selective progesterone receptor modulators 3: use in oncology, endocrinology and psychiatry

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12 December 2020

Identifiers

DOI

10.1021/JM100052K

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20355713%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

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29 January 2020

PubMed publication ID

20355713

1 reference