In vitro and in vivo pharmacological characterization of J-113397, a potent and selective non-peptidyl ORL1 receptor antagonist (Q33913544)

30 July 2017

title

In vitro and in vivo pharmacological characterization of J-113397, a potent and selective non-peptidyl ORL1 receptor antagonist (English)

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30 July 2017

Ozaki S

1

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30 July 2017

Kawamoto H

2

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30 July 2017

Itoh Y

3

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30 July 2017

Miyaji M

4

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30 July 2017

Azuma T

5

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30 July 2017

Ichikawa D

6

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30 July 2017

Nambu H

7

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30 July 2017

Iguchi T

8

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30 July 2017

Iwasawa Y

9

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30 July 2017

Ohta H

10

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30 July 2017

language of work or name

English

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publication date

1 August 2000

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European Journal of Pharmacology

30 July 2017

published in

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30 July 2017

volume

402

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30 July 2017

issue

1-2

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30 July 2017

page(s)

45-53

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[Phe1psi(CH2-NH)Gly2]nociceptin-(1-13)-NH2 is an agonist of the nociceptin (ORL1) receptor.

30 July 2017

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Pertussis Toxin-Insensitive Signaling of the ORL1 Receptor: Coupling to Gz and G16 Proteins

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[Phe1psi(CH2-NH)Gly2]nociceptin-(1-13)-NH2 acts as an agonist of the orphanin FQ/nociceptin receptor in vivo

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A new selective antagonist of the nociceptin receptor.

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Characterization of nociceptin hyperalgesia and allodynia in conscious mice

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Functional coupling of the nociceptin/orphanin FQ receptor with the G-protein-activated K+ (GIRK) channel.

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Discovery of the first potent and selective small molecule opioid receptor-like (ORL1) antagonist: 1-[(3R,4R)-1-cyclooctylmethyl-3- hydroxymethyl-4-piperidyl]-3-ethyl-1, 3-dihydro-2H-benzimidazol-2-one (J-113397)

7 January 2021

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Pharmacological characterization of acetylcholine-stimulated [35S]-GTP gamma S binding mediated by human muscarinic m1-m4 receptors: antagonist studies

7 January 2021

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Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor

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Orphanin FQ is a functional anti-opioid peptide.

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ORL1, a novel member of the opioid receptor family. Cloning, functional expression and localization

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A novel method for the detection of receptors and membrane proteins by scintillation proximity radioassay

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Unrestrained nociceptive response and disregulation of hearing ability in mice lacking the nociceptin/orphaninFQ receptor

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[Phe1phi(CH2-NH)Gly2]nociceptin-(1-13)-NH2 acts as a partial agonist at ORL1 receptor endogenously expressed in mouse N1E-115 neuroblastoma cells

7 January 2021

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Coexpression studies with endothelin receptor subtypes indicate the existence of intracellular cross-talk between ET(A) and ET(B) receptors

7 January 2021

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A potent and highly selective nonpeptidyl nociceptin/orphanin FQ receptor (ORL1) antagonist: J-113397.

7 January 2021

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7 January 2021

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Orphanin FQ: a neuropeptide that activates an opioidlike G protein-coupled receptor.

7 January 2021

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7 January 2021

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[Phe1psi(CH2-NH)Gly2]-nociceptin-(1-13)NH2, a proposed antagonist of the nociceptin receptor, is a potent and stable agonist in the rat spinal cord

7 January 2021

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10.1016/S0014-2999(00)00520-3

7 January 2021

Identifiers

DOI

1 reference

release_s6iqo4nnvzcldck2eauwf37n6i

30 July 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/s6iqo4nnvzcldck2eauwf37n6i

mapped directly with Wikidata item

24 November 2022

based on heuristic

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