Human serotonin transporter variants display altered sensitivity to protein kinase G and p38 mitogen-activated protein kinase (Q33913931)

30 July 2017

title

Human serotonin transporter variants display altered sensitivity to protein kinase G and p38 mitogen-activated protein kinase (English)

1 reference

30 July 2017

James S Sutcliffe

8

0 references

author name string

Harish C Prasad

1

1 reference

30 July 2017

Chong-Bin Zhu

2

1 reference

30 July 2017

Jacob L McCauley

3

1 reference

30 July 2017

Devadoss J Samuvel

4

1 reference

30 July 2017

Sammanda Ramamoorthy

5

1 reference

30 July 2017

Richard C Shelton

6

1 reference

30 July 2017

William A Hewlett

7

1 reference

30 July 2017

Randy D Blakely

9

1 reference

30 July 2017

language of work or name

English

0 references

publication date

29 July 2005

1 reference

Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

published in

1 reference

30 July 2017

volume

102

1 reference

30 July 2017

issue

32

1 reference

30 July 2017

page(s)

11545-11550

1 reference

A role for p38 mitogen-activated protein kinase in the regulation of the serotonin transporter: evidence for distinct cellular mechanisms involved in transporter surface expression.

30 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

Early-life blockade of the 5-HT transporter alters emotional behavior in adult mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

Neurotransmitter transporter trafficking: endocytosis, recycling, and regulation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

Evidence for sex-specific risk alleles in autism spectrum disorder

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

Multiple Rare Alleles Contribute to Low Plasma Levels of HDL Cholesterol

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

Serotonin transporter: gene, genetic disorders, and pharmacogenetics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

Serotonin transporter missense mutation associated with a complex neuropsychiatric phenotype

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

A genomewide screen of 345 families for autism-susceptibility loci

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

Evolutionary conservation predicts function of variants of the human organic cation transporter, OCT1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

Monoamine transporter gene structure and polymorphisms in relation to psychiatric and other complex disorders

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

The multiple LIM domain-containing adaptor protein Hic-5 synaptically colocalizes and interacts with the dopamine transporter

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

Alternative non-coding exons support serotonin transporter mRNA expression in the brain and gut.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

Interaction of the C-terminal region of the rat serotonin transporter with MacMARCKS modulates 5-HT uptake regulation by protein kinase C.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

Regulation of the serotonin transporter by interacting proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

Symmetrical dimer of the human dopamine transporter revealed by cross-linking Cys-306 at the extracellular end of the sixth transmembrane segment

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

A genomewide screen for autism: strong evidence for linkage to chromosomes 2q, 7q, and 16p.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

Are rare variants responsible for susceptibility to complex diseases?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

Cocaine and antidepressant-sensitive biogenic amine transporters exist in regulated complexes with protein phosphatase 2A.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

Orthostatic intolerance and tachycardia associated with norepinephrine-transporter deficiency

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

A serotonin transporter gene intron 2 polymorphic region, correlated with affective disorders, has allele-dependent differential enhancer-like properties in the mouse embryo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

Review article: roles played by 5-hydroxytryptamine in the physiology of the bowel

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

Phosphorylation and sequestration of serotonin transporters differentially modulated by psychostimulants

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

Characterization of single-nucleotide polymorphisms in coding regions of human genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

Phosphorylation and regulation of antidepressant-sensitive serotonin transporters

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

The third transmembrane domain of the serotonin transporter contains residues associated with substrate and cocaine binding

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

Alternative splicing of the human serotonin transporter gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

The serotonin system in autism

5 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

5 July 2018

https://api.crossref.org/works/10.1073%2FPNAS.0501432102

Protein kinase C activation regulates human serotonin transporters in HEK-293 cells via altered cell surface expression

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

Antidepressant- and cocaine-sensitive human serotonin transporter: molecular cloning, expression, and chromosomal localization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

Adenosine A3 receptors regulate serotonin transport via nitric oxide and cGMP.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

Serotonin in obsessions, compulsions, and the control of aggressive impulses

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

Role of serotonin in depression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

Platelet serotonin, a possible marker for familial autism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

Cloning of a serotonin transporter affected by antidepressants

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

Structure and function of the brain serotonin system

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

Clinical economics review: medical management of inflammatory bowel disease.

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0501432102

Adenosine receptor, protein kinase G, and p38 mitogen-activated protein kinase-dependent up-regulation of serotonin transporters involves both transporter trafficking and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0501432102

p38 MAPK activation elevates serotonin transport activity via a trafficking-independent, protein phosphatase 2A-dependent process

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0501432102

Screening a large reference sample to identify very low frequency sequence variants: comparisons between two genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0501432102

A human serotonin transporter mutation causes constitutive activation of transport activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0501432102

Stimulation of serotonin transport by the cyclic GMP phosphodiesterase-5 inhibitor sildenafil

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0501432102

Linkage and association analysis at the serotonin transporter (SLC6A4) locus in a rigid-compulsive subset of autism

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0501432102

Delineation of an endogenous zinc-binding site in the human dopamine transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0501432102

Evidence for biphasic effects of protein kinase C on serotonin transporter function, endocytosis, and phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0501432102

Hyperserotonemia and early infantile autism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0501432102

Developmental changes in brain serotonin synthesis capacity in autistic and nonautistic children

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0501432102

Barrel pattern formation requires serotonin uptake by thalamocortical afferents, and not vesicular monoamine release.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

Transient developmental expression of monoamine transporters in the rodent forebrain

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1183547

Increase of human platelet serotonin uptake by atypical histamine receptors

29 October 2018

1 reference

12 December 2020

Systematic screening for mutations in the coding region of the human serotonin transporter (5-HTT) gene using PCR and DGGE

1 reference

12 December 2020

Determination of external loop topology in the serotonin transporter by site-directed chemical labeling

1 reference

12 December 2020

Ultrastructural localization of the serotonin transporter in superficial and deep layers of the rat prelimbic prefrontal cortex and its spatial relationship to dopamine terminals

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0501432102

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference