Towards an understanding of the mechanism of action of praziquantel (Q33914691)

30 July 2017

Towards an understanding of the mechanism of action of praziquantel (English)

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30 July 2017

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Eric S Loker

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30 July 2017

Anthony D Aragon

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30 July 2017

Reza A Imani

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30 July 2017

Vint R Blackburn

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30 July 2017

Pauline M Cupit

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30 July 2017

Sandra D Melman

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30 July 2017

Tinopiwa Goronga

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30 July 2017

Thomas Webb

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30 July 2017

Charles Cunningham

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30 July 2017

language of work or name

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28 November 2008

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Molecular and Biochemical Parasitology

30 July 2017

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30 July 2017

164

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57-65

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on focus list of Wikimedia project

30 July 2017

ScienceSource

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cites work

Microarray based analysis of temperature and oxidative stress induced messenger RNA in Schistosoma mansoni

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Microarray analysis of gene expression induced by sexual contact in Schistosoma mansoni

5 July 2018

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The Drosophila muscle LIM protein, Mlp84B, cooperates with D-titin to maintain muscle structural integrity

5 July 2018

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Activity of praziquantel on in vitro transformed Schistosoma mansoni sporocysts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

Schistosoma mansoni: DNA microarray gene expression profiling during the miracidium-to-mother sporocyst transformation

5 July 2018

1 reference

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HTself: self-self based statistical test for low replication microarray studies

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

Blast2GO: a universal tool for annotation, visualization and analysis in functional genomics research

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

Are Ca2+ channels targets of praziquantel action?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

Gelsolin superfamily proteins: key regulators of cellular functions.

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

Regulatory pathways in ion homeostasis involving calcineurin and a calcium transporting ATPase are different between yeast and schistosomes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

Praziquantel: an urgent and exciting challenge

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

Cloning of 5' and 3' flanking regions of the Schistosoma mansoni calcineurin A gene and their characterization in transiently transformed parasites

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

F-actin and myosin II binding domains in supervillin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

5 July 2018

1 reference

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

Schistosome calcium channel beta subunits. Unusual modulatory effects and potential role in the action of the antischistosomal drug praziquantel

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

Significance analysis of microarrays applied to the ionizing radiation response

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

Resistance to praziquantel: direct evidence from Schistosoma mansoni isolated from Egyptian villagers.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

Schistosoma mansoni Ca2+-ATPase SMA2 restores viability to yeast Ca2+-ATPase-deficient strains and functions in calcineurin-mediated Ca2+ tolerance.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

Regulation of the calmodulin-stimulated protein phosphatase, calcineurin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

Schistosoma mansoni: maturation rate and drug susceptibility of different geographic isolates.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

A summary of the efficacy of praziquantel against schistosomes in animal experiments and notes on its mode of action.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

Effects of praziquantel on different developmental stages of Schistosoma mansoni in vitro and in vivo.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

Sequence and expression of a major egg antigen from Schistosoma mansoni. Homologies to heat shock proteins and alpha-crystallins.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

Schistosoma mansoni: chemotherapy of infections of different ages

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

The 86-kilodalton antigen from Schistosoma mansoni is a heat-shock protein homologous to yeast HSP-90.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

The reversible effect of glucose on the energy metabolism of Schistosoma mansoni cercariae and schistosomula

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

The facultative anaerobic energy metabolism of Schistosoma mansoni sporocysts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

A benzodiazepine derivative and praziquantel: effects on musculature of Schistosoma mansoni and Schistosoma japonicum

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

Praziquantel, a new broad-spectrum antischistosomal agent

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

Schistosoma mansoni: lack of correlation between praziquantel-induced intra-worm calcium influx and parasite death

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

Modulation of the antioxidant defence in different developmental stages of Schistosoma mansoni by praziquantel and artemether

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

Praziquantel binds Schistosoma mansoni adult worm actin.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

Dioecious Schistosoma mansoni express divergent gene repertoires regulated by pairing.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

Transcriptomics tool for the human Schistosoma blood flukes using microarray gene expression profiling.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

Sex- and stage-related sensitivity of Schistosoma mansoni to in vivo and in vitro praziquantel treatment

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

Sequence and level of endogenous expression of calcium channel beta subunits in Schistosoma mansoni displaying different susceptibilities to praziquantel

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

In vitro responses of praziquantel-resistant and -susceptible Schistosoma mansoni to praziquantel

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

Molecular cloning of Schistosoma mansoni calcineurin subunits and immunolocalization to the excretory system

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

Regulation of HSP70 gene expression during the life cycle of the parasitic helminth Schistosoma mansoni.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

The anti-schistosomal drug praziquantel is an adenosine antagonist

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886009

Effect of praziquantel on the free living stages of Schistosoma mansoni

29 October 2018

1 reference

12 December 2020

Effects of culture and praziquantel on membrane fluidity parameters of adult Schistosoma mansoni

1 reference

12 December 2020

Cytochalasin D abolishes the schistosomicidal activity of praziquantel

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12 December 2020

Influence of praziquantel and Ca2+ on the bilayer-isotropic-hexagonal transition of model membranes

1 reference

12 December 2020

The aerobic energy metabolism of Schistosoma mansoni miracidia

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12 December 2020

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12 December 2020

Aerobic to anaerobic transition in the carbohydrate metabolism of Schistosoma mansoni cercariae during transformation in vitro

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12 December 2020

The energy production of the adult Schistosoma mansoni is for a large part aerobic

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12 December 2020

Oxidative Phosphorylation in Adult Schistosoma mansoni

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12 December 2020

The effect of praziquantel treatment on glutathione concentration in Schistosoma mansoni

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12 December 2020

Increased exposure of parasite antigens at the surface of adult male Schistosoma mansoni exposed to praziquantel in vitro

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12 December 2020

10.1016/J.MOLBIOPARA.2008.11.007

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DOI

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30 July 2017

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30 July 2017

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