Pediatric phase I trial design using maximum target inhibition as the primary endpoint (Q33915053)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20460632%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

title

Pediatric phase I trial design using maximum target inhibition as the primary endpoint (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20460632%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

main subject

phase I clinical trial

0 references

author

Frank Balis

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20460632%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

author name string

Holly Meany

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20460632%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Alberta Aikin

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20460632%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Patricia Whitcomb

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20460632%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Robert F Murphy

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20460632%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Seth M Steinberg

6

1 reference

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2 February 2020

Brigitte C Widemann

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20460632%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Elizabeth Fox

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20460632%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

language of work or name

English

0 references

publication date

11 May 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20460632%20AND%20SRC:MED&resulttype=core&format=json

Journal of the National Cancer Institute

2 February 2020

published in

1 reference

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2 February 2020

volume

102

1 reference

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2 February 2020

issue

12

1 reference

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2 February 2020

page(s)

909-912

1 reference

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Dipeptide boronic acid inhibitors of dipeptidyl peptidase IV: determinants of potency and in vivo efficacy and safety

2 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886096

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886096

Phase I trial of PT-100 (PT-100), a cytokine-inducing small molecule, following chemotherapy for solid tumor malignancy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886096

Methodology of clinical trials with new molecular-targeted agents: where do we stand?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886096

5 July 2018

Cell-surface peptidases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886096

Clinical trial design for target specific anticancer agents

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886096

Clinical trial design for target-based therapy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886096

Novel endpoints and design of early clinical trials

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886096

Cell surface glycoprotein of reactive stromal fibroblasts as a potential antibody target in human epithelial cancers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886096

PT-100, a small molecule dipeptidyl peptidase inhibitor, has potent antitumor effects and augments antibody-mediated cytotoxicity via a novel immune mechanism.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886096

Tumors and their microenvironments: tilling the soil. Commentary re: A. M. Scott et al., A Phase I dose-escalation study of sibrotuzumab in patients with advanced or metastatic fibroblast activation protein-positive cancer. Clin. Cancer Res., 9: 163

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2886096

Clinical drug development for childhood cancers

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20460632

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Dose escalation trial designs based on a molecularly targeted endpoint

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20460632

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A kinetic fluorometric assay of dipeptidyl peptidase IV in viable human blood mononuclear cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20460632

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/JNCI/DJQ174

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20460632%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20460632%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

PubMed publication ID

20460632

1 reference