Increased GABAergic tone in the ventromedial hypothalamus contributes to suppression of counterregulatory responses after antecedent hypoglycemia (Q33920038)

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English	Increased GABAergic tone in the ventromedial hypothalamus contributes to suppression of counterregulatory responses after antecedent hypoglycemia	scientific article

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scholarly article

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Europe PubMed Central

30 July 2017

Increased GABAergic tone in the ventromedial hypothalamus contributes to suppression of counterregulatory responses after antecedent hypoglycemia (English)

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Europe PubMed Central

30 July 2017

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Rory J. McCrimmon

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Rory J McCrimmon

7

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author name string

Owen Chan

1

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Europe PubMed Central

30 July 2017

Haiying Cheng

2

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Europe PubMed Central

30 July 2017

Raimund Herzog

3

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Europe PubMed Central

30 July 2017

Daniel Czyzyk

4

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Europe PubMed Central

30 July 2017

Wanling Zhu

5

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Europe PubMed Central

30 July 2017

Ajin Wang

6

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Europe PubMed Central

30 July 2017

Margretta R Seashore

8

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Europe PubMed Central

30 July 2017

Robert S Sherwin

9

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Europe PubMed Central

30 July 2017

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28 March 2008

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Europe PubMed Central

30 July 2017

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Europe PubMed Central

30 July 2017

57

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Europe PubMed Central

30 July 2017

5

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Europe PubMed Central

30 July 2017

1363-1370

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Europe PubMed Central

30 July 2017

Corticotrophin-releasing factor receptors within the ventromedial hypothalamus regulate hypoglycemia-induced hormonal counterregulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5518793

5 July 2018

Activation of AMP-activated protein kinase within the ventromedial hypothalamus amplifies counterregulatory hormone responses in rats with defective counterregulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5518793

5 July 2018

Assays for measuring extracellular GABA levels and cell migration rate in acute slices

1 reference

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5 July 2018

The effect of modafinil on counter-regulatory and cognitive responses to hypoglycaemia

1 reference

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5 July 2018

Kinetic differences between the isoforms of glutamate decarboxylase: implications for the regulation of GABA synthesis

1 reference

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5 July 2018

Hypoglycaemia: the limiting factor in the glycaemic management of Type I and Type II diabetes

1 reference

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5 July 2018

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

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5 July 2018

Extracellular glucose concentrations in the rat hippocampus measured by zero-net-flux: effects of microdialysis flow rate, strain, and age.

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5 July 2018

Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5518793

5 July 2018

Alteration in brain glucose metabolism induced by hypoglycaemia in man.

1 reference

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5 July 2018

Neurocircuitry of stress: central control of the hypothalamo-pituitary-adrenocortical axis

1 reference

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5 July 2018

GABAergic neuronal activity and mRNA levels for both forms of glutamic acid decarboxylase (GAD65 and GAD67) are reduced in the diagonal band of Broca during the afternoon of proestrus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5518793

5 July 2018

Hypoglycemia-associated autonomic failure in insulin-dependent diabetes mellitus. Recent antecedent hypoglycemia reduces autonomic responses to, symptoms of, and defense against subsequent hypoglycemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5518793

5 July 2018

Regulation of gamma-aminobutyric acid synthesis in the brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5518793

5 July 2018

The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5518793

5 July 2018

Ventromedial hypothalamic lesions in rats suppress counterregulatory responses to hypoglycemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5518793

5 July 2018

The level of GAD67 protein is highly sensitive to small increases in intraneuronal gamma-aminobutyric acid levels.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5518793

5 July 2018

Adaptation in brain glucose uptake following recurrent hypoglycemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5518793

5 July 2018

Glucose modulates rat substantia nigra GABA release in vivo via ATP-sensitive potassium channels

1 reference

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5 July 2018

Brain glucose uptake and unawareness of hypoglycemia in patients with insulin-dependent diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5518793

5 July 2018

Chronic hypoglycemia increases brain glucose transport.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5518793

5 July 2018

Gamma amino butyric acid (GABA) controls anterior pituitary hormone secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5518793

5 July 2018

Increased glutamic acid decarboxylase (GAD) mRNA and GAD activity in cerebellar Purkinje cells following lesion-induced increases in cell firing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5518793

5 July 2018

Microdialysis--theory and application

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5518793

5 July 2018

Parallel increases in striatal glutamic acid decarboxylase activity and mRNA levels in rats with lesions of the nigrostriatal pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5518793

5 July 2018

Reduced neuroendocrine and symptomatic responses to subsequent hypoglycemia after 1 episode of hypoglycemia in nondiabetic humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5518793

5 July 2018

Interaction of hypothalamic GABAA and excitatory amino acid receptors controlling heart rate in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5518793

5 July 2018

Iatrogenic hypoglycemia as a cause of hypoglycemia-associated autonomic failure in IDDM. A vicious cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5518793

5 July 2018

Glutamate decarboxylase (GAD) and gamma-aminobutyric acid (GABA) in discrete nuclei of hypothalamus and substantia nigra

1 reference

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5 July 2018

Type 1 corticotropin-releasing factor receptors in the ventromedial hypothalamus promote hypoglycemia-induced hormonal counterregulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5518793

29 October 2018

Blockade of GABA(A) receptors in the ventromedial hypothalamus further stimulates glucagon and sympathoadrenal but not the hypothalamo-pituitary-adrenal response to hypoglycemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5518793

29 October 2018

Physiological and molecular characteristics of rat hypothalamic ventromedial nucleus glucosensing neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5518793

29 October 2018

Inactivation of the DMH selectively inhibits the ACTH and corticosterone responses to hypoglycemia

1 reference

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29 October 2018

Alprazolam (a benzodiazepine activating GABA receptor) reduces the neuroendocrine responses to insulin-induced hypoglycaemia in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5518793

29 October 2018

Effect of hypoglycemia on brain glycogen metabolism in vivo

1 reference

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29 October 2018

Correlation between GABA release from rat islet beta-cells and their metabolic state

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5518793

29 October 2018

Hypoglycemia-associated autonomic failure in advanced type 2 diabetes

1 reference

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29 October 2018

PVN activation is suppressed by repeated hypoglycemia but not antecedent corticosterone in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5518793

29 October 2018

Effects of antecedent hypoglycemia, hyperinsulinemia, and excess corticosterone on hypoglycemic counterregulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5518793

29 October 2018

Concomitant regulation of running activity and metabolic change by the ventromedial nucleus of the hypothalamus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5518793

29 October 2018

Upregulation of blood-brain barrier GLUT1 glucose transporter protein and mRNA in experimental chronic hypoglycemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5518793

29 October 2018

Local ventromedial hypothalamus glucopenia triggers counterregulatory hormone release

1 reference

https://pubmed.ncbi.nlm.nih.gov/18375441

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Role of Protein Phosphorylation in Regulation of Brain L-Glutamate Decarboxylase Activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/18375441

12 December 2020

based on heuristic

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Repeated 2-deoxy-D-glucose-induced glucoprivation attenuates Fos expression and glucoregulatory responses during subsequent glucoprivation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18375441

12 December 2020

based on heuristic

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Norepinephrine mediates glucoprivic-induced increase in GABA in the ventromedial hypothalamus of rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/18375441

12 December 2020

based on heuristic

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Bicuculline methiodide influences the central nervous system to produce hyperglycemia in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/18375441

12 December 2020

based on heuristic

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Turnover and release of GABA in rat cortical slices: effect of a GABA-T inhibitor, gabaculine

1 reference

https://pubmed.ncbi.nlm.nih.gov/18375441

12 December 2020

based on heuristic

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Effects of Differing Antecedent Hypoglycemia on Subsequent Counterregulation in Normal Humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/18375441

12 December 2020

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Hypoglycemia-induced inhibition of LH and stimulation of ACTH secretion in the rhesus monkey is blocked by alprazolam

1 reference

https://pubmed.ncbi.nlm.nih.gov/18375441

12 December 2020

based on heuristic

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Identifiers

10.2337/DB07-1559

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Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

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Europe PubMed Central

30 July 2017

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