Isolation of a 40-kDa Huntingtin-associated protein (Q33921816)

30 July 2017

Isolation of a 40-kDa Huntingtin-associated protein (English)

1 reference

30 July 2017

1 reference

GOA release 2020-03-11

author name string

M F Peters

series ordinal

1

1 reference

PubMed ID

11035034

30 July 2017

C A Ross

series ordinal

2

1 reference

PubMed ID

11035034

30 July 2017

language of work or name

English

0 references

publication date

16 October 2000

1 reference

Journal of Biological Chemistry

30 July 2017

1 reference

30 July 2017

276

1 reference

30 July 2017

5

1 reference

30 July 2017

3188-3194

1 reference

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

30 July 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

Glutamine repeats and neurodegenerative diseases: molecular aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

Intranuclear neuronal inclusions: a common pathogenic mechanism for glutamine-repeat neurodegenerative diseases?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

Widespread expression of Huntington's disease gene (IT15) protein product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

Huntingtin is required for neurogenesis and is not impaired by the Huntington's disease CAG expansion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

Inactivation of the mouse Huntington's disease gene homolog Hdh

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

A huntingtin-associated protein enriched in brain with implications for pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

Huntingtin-associated protein 1 (HAP1) binds to a Trio-like polypeptide, with a rac1 guanine nucleotide exchange factor domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

SH3GL3 associates with the Huntingtin exon 1 protein and promotes the formation of polygln-containing protein aggregates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

Huntingtin interacts with a family of WW domain proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

Aberrant interactions of transcriptional repressor proteins with the Huntington's disease gene product, huntingtin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

HIP-I: a huntingtin interacting protein isolated by the yeast two-hybrid system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

Huntingtin is ubiquitinated and interacts with a specific ubiquitin-conjugating enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

Huntingtin interacts with cystathionine beta-synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

Amyloid formation by mutant huntingtin: threshold, progressivity and recruitment of normal polyglutamine proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

Expansion of polyglutamine repeat in huntingtin leads to abnormal protein interactions involving calmodulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

SH3 domain-dependent association of huntingtin with epidermal growth factor receptor signaling complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

Insoluble detergent-resistant aggregates form between pathological and nonpathological lengths of polyglutamine in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

Activation of MLK2-mediated signaling cascades by polyglutamine-expanded huntingtin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

Differential association of syntrophin pairs with the dystrophin complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

Nuclear targeting of mutant Huntingtin increases toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

Ultrastructural localization and progressive formation of neuropil aggregates in Huntington's disease transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

Partial characterisation of murine huntingtin and apparent variations in the subcellular localisation of huntingtin in human, mouse and rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

Sequence of the human factor VIII-associated gene is conserved in mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

Investigation of the factor VIII intron 22 repeated region (int22h) and the associated inversion junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

The identification of a functional nuclear localization signal in the Huntington disease protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

HEAT repeats in the Huntington's disease protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

Subcellular localization of the Huntington's disease gene product in cell lines by immunofluorescence and biochemical subcellular fractionation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

Amino-terminal fragments of mutant huntingtin show selective accumulation in striatal neurons and synaptic toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

CREB-binding protein sequestration by expanded polyglutamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008099200

21 January 2018

Identifiers

DOI

10.1074/JBC.M008099200

1 reference

30 July 2017

1 reference

PubMed ID

11035034