Uric acid protects against secondary damage after spinal cord injury (Q33927539)

30 July 2017

Uric acid protects against secondary damage after spinal cord injury (English)

1 reference

30 July 2017

2

Salvatore Cuzzocrea

1 reference

30 July 2017

3

Tiziana Genovese

1 reference

30 July 2017

4

Hilary Koprowski

1 reference

30 July 2017

Gwen S Scott

1

1 reference

PubMed ID

15728348

30 July 2017

D Craig Hooper

series ordinal

5

1 reference

PubMed ID

15728348

30 July 2017

language of work or name

English

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publication date

22 February 2005

1 reference

Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

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30 July 2017

102

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30 July 2017

3483-3488

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30 July 2017

9

1 reference

Blood‐spinal cord barrier after spinal cord injury: Relation to revascularization and wound healing

30 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552934

Poly(ADP-Ribose) polymerase-1 in acute neuronal death and inflammation: a strategy for neuroprotection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552934

Multiple pathways of peroxynitrite cytotoxicity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552934

Therapeutic intervention in experimental allergic encephalomyelitis by administration of uric acid precursors.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552934

Peroxynitrite generated in the rat spinal cord induces neuron death and neurological deficits.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552934

Comparison of uric acid and ascorbic acid in protection against EAE.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552934

Serum uric acid levels in multiple sclerosis patients correlate with activity of disease and blood-brain barrier dysfunction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552934

Development and characterization of a novel, graded model of clip compressive spinal cord injury in the mouse: Part 1. Clip design, behavioral outcomes, and histopathology

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552934

Physiology and pathophysiology of poly(ADP-ribosyl)ation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552934

Nitrotyrosine formation and its role in various pathological conditions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552934

The peroxynitrite scavenger uric acid prevents inflammatory cell invasion into the central nervous system in experimental allergic encephalomyelitis through maintenance of blood-central nervous system barrier integrity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552934

The role of reactive nitrogen species in secondary spinal cord injury: formation of nitric oxide, peroxynitrite, and nitrated protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552934

S-nitroso-N-acetylpenicillamine and nitroprusside induce apoptosis in a neuronal cell line by the production of different reactive molecules

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552934

Uric acid, a peroxynitrite scavenger, inhibits CNS inflammation, blood-CNS barrier permeability changes, and tissue damage in a mouse model of multiple sclerosis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552934

Uric acid oxidation by peroxynitrite: multiple reactions, free radical formation, and amplification of lipid oxidation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552934

Pathogenesis and pharmacological strategies for mitigating secondary damage in acute spinal cord injury

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552934

Uric acid protects neurons against excitotoxic and metabolic insults in cell culture, and against focal ischemic brain injury in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552934

Peroxynitrite and hydrogen peroxide induced cell death in the NSC34 neuroblastoma x spinal cord cell line: role of poly (ADP-ribose) polymerase.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552934

Uric acid, a natural scavenger of peroxynitrite, in experimental allergic encephalomyelitis and multiple sclerosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552934

Prevention of experimental allergic encephalomyelitis by targeting nitric oxide and peroxynitrite: implications for the treatment of multiple sclerosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552934

A quantitative spatial analysis of the blood-spinal cord barrier. I. Permeability changes after experimental spinal contusion injury.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552934

Pathophysiology of spinal cord trauma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552934

Molecular evolution of the urate oxidase-encoding gene in hominoid primates: nonsense mutations

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552934

Involvement of lipid peroxidation in CNS injury

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552934

Two independent mutational events in the loss of urate oxidase during hominoid evolution

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552934

Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552934

iNOS and nitrotyrosine expression after spinal cord injury

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500307102

Poly(ADP-ribose) polymerase activity contributes to peroxynitrite-induced spinal cord neuronal cell death in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500307102

Local acute application of BDNF in the lesioned spinal cord anti-inflammatory and anti-oxidant effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500307102

Peroxynitrite-induced oligodendrocyte toxicity is not dependent on poly(ADP-ribose) polymerase activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500307102

Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma, reduces acute inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500307102

Experimental meningitis in the rat: protection by uric acid at human physiological blood concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500307102

The central nervous system inflammatory response to neurotropic virus infection is peroxynitrite dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500307102

Comparison of iNOS inhibition by antisense and pharmacological inhibitors after spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500307102

A reassessment of the peroxynitrite scavenging activity of uric acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500307102

Chemosensitization and radiosensitization of human cancer by antisense anti-MDM2 oligonucleotides: in vitro and in vivo activities and mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500307102

Pharmacologic inhibition of poly(ADP-ribose) polymerase is neuroprotective following traumatic brain injury in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500307102

Inhibition by uric acid of free radicals that damage biological molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500307102

Uric acid levels in sera from patients with multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500307102

Uric acid is reduced in the substantia nigra in Parkinson's disease: effect on dopamine oxidation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500307102

Observations on serum uric acid levels and the risk of idiopathic Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500307102

The urate and xanthine concentrations in the cerebrospinal fluid in patients with vascular dementia of the Binswanger type, Alzheimer type dementia, and Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500307102

Hypouricemia, abnormal renal tubular urate transport, and plasma natriuretic factor(s) in patients with Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500307102

Plasma antioxidants are similarly depleted in mild cognitive impairment and in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500307102

Early anti-inflammatory treatment reduces lipid peroxidation and protein nitration after spinal cord injury in rats.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552934

Uric acid levels in patients with multiple sclerosis: analysis in mono- and dizygotic twins

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552934

Traumatic brain injury in mice deficient in poly-ADP(ribose) polymerase: a preliminary report.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552934

Reaction of uric acid with peroxynitrite and implications for the mechanism of neuroprotection by uric acid

29 October 2018

1 reference

12 December 2020

Protection of myelin basic protein immunized mice from free-radical mediated inflammatory cell invasion of the central nervous system by the natural peroxynitrite scavenger uric acid

1 reference

12 December 2020

Prospects for the treatment of multiple sclerosis by raising serum levels of uric acid, a scavenger of peroxynitrite

1 reference

12 December 2020

ICAM-1 upregulation in the spinal cords of PLSJL mice with experimental allergic encephalomyelitis is dependent upon TNF-alpha production triggered by the loss of blood-brain barrier integrity

1 reference

12 December 2020

Myeloperoxidase activity as a quantitative assessment of neutrophil infiltration into ischemic myocardium

1 reference

12 December 2020

Efficacy of the 21-aminosteroid U74006F in improving neurological recovery after spinal cord injury in rats

1 reference

12 December 2020

Effect of peroxynitrite on the mitochondrial respiratory chain: differential susceptibility of neurones and astrocytes in primary culture

1 reference

12 December 2020

Cellular inflammatory response after spinal cord injury in Sprague-Dawley and Lewis rats

1 reference

12 December 2020

Role of neutrophils in spinal cord injury in the rat

1 reference

12 December 2020

Acute inflammatory response in spinal cord following impact injury

1 reference

12 December 2020

Peroxynitrite production and activation of poly (adenosine diphosphate-ribose) synthetase in spinal cord injury

1 reference

12 December 2020

Cyclosporin-A inhibits lipid peroxidation after spinal cord injury in rats

1 reference

12 December 2020

Arachidonic acid-induced oxidative injury to cultured spinal cord neurons

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0500307102

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference

PubMed ID

15728348