Near-precise interchromosomal recombination and functional DNA topoisomerase II cleavage sites at MLL and AF-4 genomic breakpoints in treatment-related acute lymphoblastic leukemia with t(4;11) translocation (Q33933823)

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English	Near-precise interchromosomal recombination and functional DNA topoisomerase II cleavage sites at MLL and AF-4 genomic breakpoints in treatment-related acute lymphoblastic leukemia with t(4;11) translocation	scientific article

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scholarly article

1 reference

Europe PubMed Central

30 July 2017

Near-precise interchromosomal recombination and functional DNA topoisomerase II cleavage sites at MLL and AF-4 genomic breakpoints in treatment-related acute lymphoblastic leukemia with t(4;11) translocation (English)

1 reference

Europe PubMed Central

30 July 2017

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based on heuristic

inferred from title

lymphoblastic leukemia

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based on heuristic

inferred from title

author name string

B D Lovett

1

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Europe PubMed Central

30 July 2017

L Lo Nigro

2

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Europe PubMed Central

30 July 2017

E F Rappaport

3

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Europe PubMed Central

30 July 2017

I A Blair

4

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Europe PubMed Central

30 July 2017

N Osheroff

5

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Europe PubMed Central

30 July 2017

N Zheng

6

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Europe PubMed Central

30 July 2017

M D Megonigal

7

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Europe PubMed Central

30 July 2017

W R Williams

8

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Europe PubMed Central

30 July 2017

P C Nowell

9

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Europe PubMed Central

30 July 2017

C A Felix

10

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Europe PubMed Central

30 July 2017

language of work or name

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publication date

7 August 2001

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Europe PubMed Central

30 July 2017

Proceedings of the National Academy of Sciences of the United States of America

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Europe PubMed Central

30 July 2017

98

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Europe PubMed Central

30 July 2017

17

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Europe PubMed Central

30 July 2017

9802-9807

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Europe PubMed Central

30 July 2017

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC55533/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Leukemias related to treatment with DNA topoisomerase II inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55533

5 July 2018

Etoposide metabolites enhance DNA topoisomerase II cleavage near leukemia-associated MLL translocation breakpoints

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55533

5 July 2018

Detection of leukemia-associated MLL-GAS7 translocation early during chemotherapy with DNA topoisomerase II inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55533

5 July 2018

Duplicated regions of AF-4 intron 4 at t(4;11) translocation breakpoints

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55533

5 July 2018

Association of CYP3A4 genotype with treatment-related leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55533

5 July 2018

t(11;22)(q23;q11.2) In acute myeloid leukemia of infant twins fuses MLL with hCDCrel, a cell division cycle gene in the genomic region of deletion in DiGeorge and velocardiofacial syndromes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55533

5 July 2018

Panhandle polymerase chain reaction amplifies MLL genomic translocation breakpoint involving unknown partner gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55533

5 July 2018

A precise interchromosomal reciprocal exchange between hot spots for cleavable complex formation by topoisomerase II in amsacrine-treated Chinese hamster ovary cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55533

5 July 2018

Panhandle PCR strategy to amplify MLL genomic breakpoints in treatment-related leukemias

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55533

5 July 2018

Exon/intron structure of the human AF-4 gene, a member of the AF-4/LAF-4/FMR-2 gene family coding for a nuclear protein with structural alterations in acute leukaemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55533

5 July 2018

The secondary leukemias: challenges and research directions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55533

5 July 2018

Structure and mechanism of DNA topoisomerase II

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55533

5 July 2018

When good enzymes go bad: conversion of topoisomerase II to a cellular toxin by antineoplastic drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55533

5 July 2018

O-demethylation of epipodophyllotoxins is catalyzed by human cytochrome P450 3A4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55533

5 July 2018

Molecular analysis of 13 cases of MLL/11q23 secondary acute leukemia and identification of topoisomerase II consensus-binding sequences near the chromosomal breakpoint of a secondary leukemia with the t(4;11).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55533

5 July 2018

Mechanism of action of antitumor drug etoposide: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55533

5 July 2018

Illegitimate recombination mediated by calf thymus DNA topoisomerase II in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55533

5 July 2018

Local sequence requirements for DNA cleavage by mammalian topoisomerase II in the presence of doxorubicin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55533

5 July 2018

Role of the semi-quinone free radical of the anti-tumour agent etoposide (VP-16-213) in the inactivation of single- and double-stranded phi X174 DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55533

5 July 2018

Distribution of topoisomerase II cleavage sites in simian virus 40 DNA and the effects of drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55533

5 July 2018

Local base sequence preferences for DNA cleavage by mammalian topoisomerase II in the presence of amsacrine or teniposide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55533

5 July 2018

A DNA damage repair mechanism is involved in the origin of chromosomal translocations t(4;11) in primary leukemic cells.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.171309898

21 January 2018

Use of yeast in the study of anticancer drugs targeting DNA topoisomerases: expression of a functional recombinant human DNA topoisomerase II alpha in yeast

1 reference

https://pubmed.ncbi.nlm.nih.gov/11493704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chromosome band 11q23 translocation breakpoints are DNA topoisomerase II cleavage sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/11493704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spontaneous DNA lesions poison human topoisomerase IIalpha and stimulate cleavage proximal to leukemic 11q23 chromosomal breakpoints

1 reference

https://pubmed.ncbi.nlm.nih.gov/11493704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Type II DNA topoisomerase from Saccharomyces cerevisiae is a stable dimer

1 reference

https://pubmed.ncbi.nlm.nih.gov/11493704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Considerable plasma levels of a cytotoxic etoposide metabolite in patients undergoing high-dose chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/11493704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of action of eukaryotic topoisomerase II and drugs targeted to the enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/11493704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secondary leukemias induced by topoisomerase-targeted drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/11493704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and sequence analysis of four t(9;11) therapy-related leukemia breakpoints

1 reference

https://pubmed.ncbi.nlm.nih.gov/11493704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bone marrow transplantation in pediatric patients with therapy-related myelodysplasia and leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/11493704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chromosome recombination and defective genome segregation induced in Chinese hamster cells by the topoisomerase II inhibitor VM-26

1 reference

https://pubmed.ncbi.nlm.nih.gov/11493704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secondary acute myeloid leukemia in children previously treated with alkylating agents, intercalating topoisomerase II inhibitors, and irradiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11493704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.171309898

1 reference

Europe PubMed Central

30 July 2017

2001PNAS...98.9802L

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1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

ResearchGate publication ID

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