A human surfactant peptide-elastase inhibitor construct as a treatment for emphysema (Q33934859)

30 July 2017

title

A human surfactant peptide-elastase inhibitor construct as a treatment for emphysema (English)

1 reference

30 July 2017

1 reference

Frank Guarnieri

1

1 reference

30 July 2017

Jean L Spencer

2

1 reference

30 July 2017

Edgar C Lucey

3

1 reference

30 July 2017

Matthew A Nugent

4

1 reference

30 July 2017

Phillip J Stone

5

1 reference

30 July 2017

language of work or name

English

0 references

publication date

1 June 2010

1 reference

30 July 2017

number of pages

6

1 reference

Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

1 reference

30 July 2017

volume

107

1 reference

30 July 2017

issue

23

1 reference

30 July 2017

page(s)

10661-10666

1 reference

Low rates of Pseudomonas aeruginosa misidentification in isolates from cystic fibrosis patients

30 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890802

Functional selectivity of EGF family peptide growth factors: implications for cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890802

Surfactant respiratory therapy using Surfaxin/sinapultide

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890802

Lung infections after cancer chemotherapy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890802

Aerosol antibiotics: considerations in pharmacological and clinical evaluation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890802

Physicochemical, pharmacological and pharmacokinetic properties of the zwitterionic antihistamines cetirizine and levocetirizine

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890802

Novel long-acting bronchodilators for COPD and asthma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890802

Denufosol: a review of studies with inhaled P2Y(2) agonists that led to Phase 3.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890802

The development of anticholinergics in the management of COPD.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890802

Polymyxin antibiotics for gram-negative infections

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890802

Long-acting beta2-agonists for chronic asthma in adults and children where background therapy contains varied or no inhaled corticosteroid

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890802

New insights into the inhibition of human neutrophil elastase by heparin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890802

Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890802

Recent advances in MMP inhibitor design

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890802

Systemic delivery of drugs to humans via inhalation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890802

Toxicity of polymyxins: a systematic review of the evidence from old and recent studies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890802

The significance of different formulations of aerosolized colistin.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890802

Aerosolized colistin for the treatment of nosocomial pneumonia due to multidrug-resistant Gram-negative bacteria in patients without cystic fibrosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890802

Content-dependent activity of lung surfactant protein B in mixtures with lipids

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890802

Synthetic inhibitors of elastase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890802

Role of alpha-macroglobulin-elastase complexes in the pathogenesis of elastase-induced emphysema in hamsters

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890802

A linear equation that describes the steady-state kinetics of enzymes and subcellular particles interacting with tightly bound inhibitors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890802

The behavior and significance of slow-binding enzyme inhibitors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890802

Evaluation of methods for estimating the dissociation constant of tight binding enzyme inhibitors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890802

Elastase secretion by stimulated macrophages. Characterization and regulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890802

Comparison of functional efficacy of surfactant protein B analogues in lavaged rats

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1001349107

Effects of including an N-terminal insertion region and arginine-mimetic side chains in helical peptoid analogues of lung surfactant protein B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1001349107

Efficacy of synthetic peptide-containing surfactant in the treatment of respiratory distress syndrome in preterm infant rhesus monkeys.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1001349107

P2X(7) purinergic receptors and extracellular ATP mediate apoptosis of human monocytes/macrophages infected with Mycobacterium tuberculosis reducing the intracellular bacterial viability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1001349107

Selective inhibition of ADAM metalloproteases as a novel approach for modulating ErbB pathways in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1001349107

Sleep-predominant lowering of ambulatory blood pressure by bedtime inhalation of a novel muscarinic M3 receptor antagonist: a new "bronchoantihypertensive" strategy targeting the lung in hypertension with chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1001349107

Ultrastructural changes in hamster lung four hours to twenty-four days after exposure to elastase

21 January 2018

1 reference

12 December 2020

Effects of oligopeptide chloromethylketone administered after elastase: renal toxicity and lack of prevention of experimental emphysema

1 reference

12 December 2020

The effects of small doses of oligopeptide elastase inhibitors on elastase-induced emphysema in hamsters: a dose-response study

1 reference

12 December 2020

Dose response of elastase-induced emphysema in hamsters

1 reference

12 December 2020

The fate of neutrophil elastase incorporated by human alveolar macrophages

1 reference

12 December 2020

Human Neutrophil Elastase Does not Bind to Alpha1-Protease Inhibitor that Has Been Exposed to Activated Human Neutrophils

1 reference

12 December 2020

An 18-month study of the effects on hamster lungs of intratracheally administered human neutrophil elastase

1 reference

12 December 2020

Induction and exacerbation of emphysema in hamsters with human neutrophil elastase inactivated reversibly by a peptide boronic acid

1 reference

12 December 2020

Biochemistry and pharmacology of ICI 200,880, a synthetic peptide inhibitor of human neutrophil elastase

1 reference

12 December 2020

A polymer-bound elastase inhibitor is effective in preventing human neutrophil elastase-induced emphysema

1 reference

12 December 2020

Covalently linking a peptidyl carbamate elastase inhibitor to a hydrophilic polymer increases its effectiveness in preventing emphysema and secretory cell metaplasia in the hamster

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1001349107

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference