Targeted degradation of the retinoblastoma protein by human papillomavirus E7-E6 fusion proteins (Q33937962)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1321031%20AND%20SRC:MED&resulttype=core&format=json

14 September 2019

title

Targeted degradation of the retinoblastoma protein by human papillomavirus E7-E6 fusion proteins (English)

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14 September 2019

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13 September 2022

author name string

M. Scheffner

1

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13 September 2022

K. Münger

2

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13 September 2022

J. M. Huibregtse

3

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13 September 2022

P. M. Howley

4

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13 September 2022

language of work or name

English

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publication date

1 July 1992

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full work available at URL

14 September 2019

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1321031/pdf/?tool=EBI

file format

Portable Document Format

online access status

open access

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1321031/?tool=EBI

13 September 2022

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https://europepmc.org/articles/PMC556717

13 September 2022

1 reference

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https://europepmc.org/articles/PMC556717?pdf=render

13 September 2022

file format

Portable Document Format

online access status

open access

content deliverer

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1321031

https://europepmc.org/articles/pmc556717?pdf=render

13 September 2022

file format

Portable Document Format

online access status

open access

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https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fj.1460-2075.1992.tb05307.x

6 December 2023

1 reference

10.1002/J.1460-2075.1992.TB05307.X

Crossref

DOI

https://api.crossref.org/works/10.1002/J.1460-2075.1992.TB05307.X

http://onlinelibrary.wiley.com/wol1/doi/10.1002/j.1460-2075.1992.tb05307.x/fullpdf

6 December 2023

1 reference

10.1002/J.1460-2075.1992.TB05307.X

Crossref

DOI

https://api.crossref.org/works/10.1002/J.1460-2075.1992.TB05307.X

6 December 2023

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1321031%20AND%20SRC:MED&resulttype=core&format=json

14 September 2019

volume

11

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14 September 2019

page(s)

2425-2431

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14 September 2019

issue

7

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1321031%20AND%20SRC:MED&resulttype=core&format=json

Two Distinct Mechanisms Regulate the Levels of a Cellular Tumor Antigen, p53

14 September 2019

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Post-Translational Regulation of the 54K Cellular Tumor Antigen in Normal and Transformed Cells

5 July 2018

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Structural and transcriptional analysis of human papillomavirus type 16 sequences in cervical carcinoma cell lines

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Transcription of human papillomavirus type 16 early genes in a cervical cancer and a cancer-derived cell line and identification of the E7 protein

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5 July 2018

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5 July 2018

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Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product

5 July 2018

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Prediction of similar transforming regions in simian virus 40 large T, adenovirus E1A, and myc oncoproteins

5 July 2018

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The E7 open reading frame of human papillomavirus type 16 encodes a transforming gene.

5 July 2018

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SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene

5 July 2018

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Molecular and cytogenetic analysis of immortalized human primary keratinocytes obtained after transfection with human papillomavirus type 16 DNA.

5 July 2018

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The human papillomavirus type 16 E7 gene encodes transactivation and transformation functions similar to those of adenovirus E1A.

5 July 2018

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Inducible and constitutive enhancer domains in the noncoding region of human papillomavirus type 18

5 July 2018

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The E6-E7 region of human papillomavirus type 18 is sufficient for transformation of NIH 3T3 and rat-1 cells

5 July 2018

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Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product

5 July 2018

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HPV16 E6 and E7 proteins cooperate to immortalize human foreskin keratinocytes

5 July 2018

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Heterogeneity of the human papillomavirus group.

5 July 2018

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The cellular 107K protein that binds to adenovirus E1A also associates with the large T antigens of SV40 and JC virus

5 July 2018

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The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product

5 July 2018

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Identification of a transforming gene of human papillomavirus type 16

5 July 2018

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Papillomavirus polypeptides E6 and E7 are zinc-binding proteins

5 July 2018

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Identification of human papillomavirus type 18 transforming genes in immortalized and primary cells

5 July 2018

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Human papillomavirus type 16 transformation of primary human embryonic fibroblasts requires expression of open reading frames E6 and E7

5 July 2018

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Intracellular localization and DNA-binding properties of human papillomavirus type 18 E6 protein expressed with a baculovirus vector

5 July 2018

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An N-terminal transformation-governing sequence of SV40 large T antigen contributes to the binding of both p110Rb and a second cellular protein, p120.

5 July 2018

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5 July 2018

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The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes

5 July 2018

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Quantitative keratinocyte assay detects two biological activities of human papillomavirus DNA and identifies viral types associated with cervical carcinoma

5 July 2018

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Comparison of the in vitro transforming activities of human papillomavirus types.

5 July 2018

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Transformation of human fibroblasts and keratinocytes with human papillomavirus type 16 DNA.

5 July 2018

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Degradation of proteins by the ubiquitin-mediated proteolytic pathway

5 July 2018

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The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

5 July 2018

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Transcriptional activation by the papillomavirus E6 zinc finger oncoprotein.

5 July 2018

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Association of human papillomavirus types 16 and 18 E6 proteins with p53.

5 July 2018

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The E7 proteins of the nononcogenic human papillomavirus type 6b (HPV-6b) and of the oncogenic HPV-16 differ in retinoblastoma protein binding and other properties

5 July 2018

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The region of the HPV E7 oncoprotein homologous to adenovirus E1a and Sv40 large T antigen contains separate domains for Rb binding and casein kinase II phosphorylation

5 July 2018

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In vitro biological activities of the E6 and E7 genes vary among human papillomaviruses of different oncogenic potential

5 July 2018

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Antibodies specific for the human retinoblastoma protein identify a family of related polypeptides

5 July 2018

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A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18

5 July 2018

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Degradation of p53 can be targeted by HPV E6 sequences distinct from those required for p53 binding and trans-activation

5 July 2018

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The full-length E6 protein of human papillomavirus type 16 has transforming and trans-activating activities and cooperates with E7 to immortalize keratinocytes in culture

5 July 2018

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Expression of RB and p53 proteins in HPV-positive and HPV-negative cervical carcinoma cell lines.

5 July 2018

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The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines

5 July 2018

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Biochemical and biological differences between E7 oncoproteins of the high- and low-risk human papillomavirus types are determined by amino-terminal sequences

5 July 2018

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Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

5 July 2018

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T antigen is bound to a host protein in SY40-transformed cells

5 July 2018

1 reference

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E6 protein of human papillomavirus type 18 binds zinc.

5 July 2018

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Association between poor prognosis in early-stage invasive cervical carcinomas and non-detection of HPV DNA

29 October 2018

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12 December 2020

SV40 large T antigen binds preferentially to an underphosphorylated member of the retinoblastoma susceptibility gene product family

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12 December 2020

Adenovirus E1b-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kd cellular protein in transformed cells

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12 December 2020

Immortalization of primary rat cells by human papillomavirus type 16 subgenomic DNA fragments controlled by the SV40 promoter

1 reference

12 December 2020

10.1002/J.1460-2075.1992.TB05307.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1321031%20AND%20SRC:MED&resulttype=core&format=json

14 September 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1321031%20AND%20SRC:MED&resulttype=core&format=json

14 September 2019

1 reference