Mobile elements and the human genome (Q33938490)

30 July 2017

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title

Mobile elements and the human genome (English)

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30 July 2017

Prak ET

1

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30 July 2017

Kazazian HH Jr

series ordinal

2

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30 July 2017

publication date

1 November 2000

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30 July 2017

published in

Nature Reviews Genetics

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30 July 2017

volume

1

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30 July 2017

issue

2

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30 July 2017

page(s)

134-144

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Interspersed repeats and other mementos of transposable elements in mammalian genomes

30 July 2017

cites work

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7 January 2021

Many human L1 elements are capable of retrotransposition

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7 January 2021

Rapid amplification of a retrotransposon subfamily is evolving the mouse genome

1 reference

7 January 2021

Unit-length line-1 transcripts in human teratocarcinoma cells

1 reference

7 January 2021

Reverse transcription of R2Bm RNA is primed by a nick at the chromosomal target site: A mechanism for non-LTR retrotransposition

1 reference

7 January 2021

Identification of the endonuclease domain encoded by R2 and other site-specific, non-long terminal repeat retrotransposable elements

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7 January 2021

Human L1 retrotransposon encodes a conserved endonuclease required for retrotransposition

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7 January 2021

Integration of retroposable elements in mammals: selection of target sites

1 reference

7 January 2021

Characterization of a non-long terminal repeat retrotransposon cDNA (L1Tc) from Trypanosoma cruzi: homology of the first ORF with the ape family of DNA repair enzymes.

1 reference

7 January 2021

Targeting of human retrotransposon integration is directed by the specificity of the L1 endonuclease for regions of unusual DNA structure.

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7 January 2021

The impact of L1 retrotransposons on the human genome

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7 January 2021

Exon shuffling by L1 retrotransposition

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7 January 2021

The age and evolution of non-LTR retrotransposable elements

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7 January 2021

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7 January 2021

Erratum: Retrotransposition of a bacterial group II intron

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7 January 2021

Retrohoming of a Bacterial Group II Intron

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7 January 2021

Retrotransposition of a mouse IAP sequence tagged with an indicator gene

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7 January 2021

Intracisternal A-type particles express their proteinase in a separate reading frame by translational frameshifting, similar to D-type retroviruses

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7 January 2021

The viruses in all of us: characteristics and biological significance of human endogenous retrovirus sequences

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7 January 2021

Human endogenous retroviral element K10 (HERV-K10) encodes a full-length gag homologous 73-kDa protein and a functional protease

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7 January 2021

Human endogenous retrovirus K10 encodes a functional integrase.

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7 January 2021

Identification of an active reverse transcriptase enzyme encoded by a human endogenous HERV-K retrovirus

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7 January 2021

An almost-intact human endogenous retrovirus K on human chromosome 7.

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7 January 2021

Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans

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7 January 2021

Human-specific integrations of the HERV-K endogenous retrovirus family

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7 January 2021

Defective retroviruses can disperse in the human genome by intracellular transposition

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7 January 2021

Apparent recombinants between virus-liKE (VL30) and murine leukemia virus-related sequences in mouse DNA

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7 January 2021

The molecular basis of the obese mutation in ob2J mice

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7 January 2021

Novel mouse type D endogenous proviruses and ETn elements share long terminal repeat and internal sequences

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7 January 2021

The DNA sequence of human chromosome 21

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7 January 2021

Tiggers and DNA transposon fossils in the human genome

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7 January 2021

Resident aliens: the Tc1/mariner superfamily of transposable elements

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7 January 2021

Mariner transposons in humans

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7 January 2021

Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells

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7 January 2021

Trans-kingdom transposition of the Drosophila element mariner within the protozoan Leishmania.

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7 January 2021

Transposon Tc1 of the nematode Caenorhabditis elegans jumps in human cells.

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7 January 2021

The RAG proteins and V(D)J recombination: complexes, ends, and transposition

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7 January 2021

RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination

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7 January 2021

Epstein-Barr virus infection of T cells: implications for altered T-lymphocyte activation, repertoire development and autoimmunity

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7 January 2021

Does SINE evolution preclude Alu function?

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7 January 2021

Alu repeats and human disease

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7 January 2021

Developmental and cell type specificity of LINE-1 expression in mouse testis: implications for transposition

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7 January 2021

Ancestral, mammalian-wide subfamilies of LINE-1 repetitive sequences

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7 January 2021

The age of Alu subfamilies

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7 January 2021

Retropositional parasitism of SINEs on LINEs: identification of SINEs and LINEs in elasmobranchs

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7 January 2021

SINEs and LINEs share common 3' sequences: a review.

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7 January 2021

Potential Alu function: regulation of the activity of double-stranded RNA-activated kinase PKR.

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7 January 2021

LINEs and Alus--the polyA connection

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7 January 2021

A human Alu RNA-binding protein whose expression is associated with accumulation of small cytoplasmic Alu RNA

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7 January 2021

The DNA sequence of human chromosome 22

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7 January 2021

Human LINE retrotransposons generate processed pseudogenes

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7 January 2021

Haemophilia A resulting from de novo insertion of L1 sequences represents a novel mechanism for mutation in man.

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7 January 2021

Isolation of an active human transposable element

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7 January 2021

A new retrotransposable human L1 element from the LRE2 locus on chromosome 1q produces a chimaeric insertion

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7 January 2021

Insertion of a 5' truncated L1 element into the 3' end of exon 44 of the dystrophin gene resulted in skipping of the exon during splicing in a case of Duchenne muscular dystrophy

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7 January 2021

Positional cloning of the gene for X-linked retinitis pigmentosa 2

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7 January 2021

Full-length human L1 insertions retain the capacity for high frequency retrotransposition in cultured cells

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7 January 2021

A new exon created by intronic insertion of a rearranged LINE-1 element as the cause of chronic granulomatous disease

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7 January 2021

Molecular evidence for a relationship between LINE-1 elements and X chromosome inactivation: the Lyon repeat hypothesis

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7 January 2021

X-chromosome inactivation: a repeat hypothesis

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7 January 2021

An estimated frequency of endogenous insertional mutations in humans

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7 January 2021

The consensus sequence of a major Alu subfamily contains a functional retinoic acid response element

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7 January 2021

Mobile elements inserted in the distant past have taken on important functions

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7 January 2021

Transcriptional silencer of the Wilms' tumor gene WT1 contains an Alu repeat

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7 January 2021

Apolipoprotein(a) gene enhancer resides within a LINE element

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7 January 2021

Solitary HERV-K LTRs possess bi-directional promoter activity and contain a negative regulatory element in the U5 region

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7 January 2021

Transduction of 3'-flanking sequences is common in L1 retrotransposition

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7 January 2021

Frequent human genomic DNA transduction driven by LINE-1 retrotransposition

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7 January 2021

Unequal homologous recombination between LINE-1 elements as a mutational mechanism in human genetic disease

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7 January 2021

LINE-1 elements at the sites of molecular rearrangements in Alport syndrome-diffuse leiomyomatosis

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7 January 2021

One short well conserved region of Alu-sequences is involved in human gene rearrangements and has homology with prokaryotic chi.

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7 January 2021

A recombination hotspot responsible for two inherited peripheral neuropathies is located near a mariner transposon-like element.

1 reference

7 January 2021

Sequences at the somatic recombination sites of immunoglobulin light-chain genes

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7 January 2021

Tn10 transposition via a DNA hairpin intermediate

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7 January 2021

Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system

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7 January 2021

Rejoining of DNA by the RAG1 and RAG2 proteins

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7 January 2021

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7 January 2021

New insights into V(D)J recombination and its role in the evolution of the immune system

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7 January 2021

Capture of retrotransposon DNA at the sites of chromosomal double-strand breaks

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7 January 2021

Patching broken chromosomes with extranuclear cellular DNA

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7 January 2021

Retrotransposon reverse-transcriptase-mediated repair of chromosomal breaks

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7 January 2021

DNA transposition by the RAG1 and RAG2 proteins: a possible source of oncogenic translocations

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7 January 2021

Members of the SRY family regulate the human LINE retrotransposons

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7 January 2021

Cytosine methylation of repeated sequences in eukaryotes: the role of DNA pairing

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7 January 2021

Creation of genomic methylation patterns

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7 January 2021

Transcription of IAP endogenous retroviruses is constrained by cytosine methylation

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7 January 2021

Asymmetric methylation in the hypermethylated CpG promoter region of the human L1 retrotransposon

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7 January 2021

Nonmethylated transposable elements and methylated genes in a chordate genome

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7 January 2021

Cytosine methylation and the ecology of intragenomic parasites

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7 January 2021

The Role of DNA Methylation in Invertebrates: Developmental Regulation or Genome Defense?

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7 January 2021

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

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7 January 2021

Mut-7 of C. elegans, required for transposon silencing and RNA interference, is a homolog of Werner syndrome helicase and RNaseD.

1 reference

7 January 2021

The rde-1 gene, RNA interference, and transposon silencing in C. elegans

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7 January 2021

Copy number control of a transposable element, the I factor, a LINE-like element in Drosophila.

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7 January 2021

Taming of transposable elements by homology-dependent gene silencing.

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7 January 2021

Telomerase catalytic subunit homologs from fission yeast and human

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7 January 2021

Reversing time: origin of telomerase

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7 January 2021

Telomerase and retrotransposons: which came first?

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7 January 2021

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7 January 2021

L1 (LINE-1) retrotransposon evolution and amplification in recent human history

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7 January 2021

Standardized nomenclature for Alu repeats

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7 January 2021

Molecular evidence from retroposons that whales form a clade within even-toed ungulates.

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7 January 2021

Simple and efficient generation in vitro of nested deletions and inversions: Tn5 intramolecular transposition

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7 January 2021

Chromosomal transposition of a Tc1/mariner-like element in mouse embryonic stem cells

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7 January 2021

Repeat-induced gene silencing in mammals.

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7 January 2021

Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system

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7 January 2021

Mobile group II introns of yeast mitochondrial DNA are novel site-specific retroelements

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7 January 2021

Group II introns designed to insert into therapeutically relevant DNA target sites in human cells

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7 January 2021

High frequency retrotransposition in cultured mammalian cells

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7 January 2021

Reverse Transcriptase Encoded by a Human Transposable Element

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7 January 2021

The human LINE-1 reverse transcriptase:effect of deletions outside the common reverse transcriptase domain

1 reference

7 January 2021

An in vivo assay for the reverse transcriptase of human retrotransposon L1 in Saccharomyces cerevisiae

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7 January 2021

Cytoplasmic ribonucleoprotein complexes containing human LINE-1 protein and RNA

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7 January 2021

Sequence-specific single-strand RNA binding protein encoded by the human LINE-1 retrotransposon

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7 January 2021

Identifiers

DOI

10.1038/35038572

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Dimensions Publication ID

30 July 2017

1005898043

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