IL-1alpha, IL-1beta, and IFN-gamma mark beta cells for Fas-dependent destruction by diabetogenic CD4(+) T lymphocytes (Q33938806)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10683375%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

title

IL-1alpha, IL-1beta, and IFN-gamma mark beta cells for Fas-dependent destruction by diabetogenic CD4(+) T lymphocytes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10683375%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

author

Joan Verdaguer Autonell

2

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4 November 2019

author name string

A Amrani

1

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4 November 2019

S Thiessen

3

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4 November 2019

S Bou

4

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4 November 2019

P Santamaria

5

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4 November 2019

language of work or name

English

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publication date

1 February 2000

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Journal of Clinical Investigation

4 November 2019

published in

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4 November 2019

volume

105

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4 November 2019

page(s)

459-468

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4 November 2019

issue

4

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Prevalent CD8(+) T cell response against one peptide/MHC complex in autoimmune diabetes

4 November 2019

cites work

1 reference

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Perforin-independent beta-cell destruction by diabetogenic CD8(+) T lymphocytes in transgenic nonobese diabetic mice

5 July 2018

1 reference

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In autoimmune diabetes the transition from benign to pernicious insulitis requires an islet cell response to tumor necrosis factor alpha.

5 July 2018

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The role of the antigen-presenting cell in Fas-mediated direct and bystander killing: potential in vivo function of Fas in experimental allergic encephalomyelitis

5 July 2018

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The role of macrophages in T cell-mediated autoimmune diabetes in nonobese diabetic mice

5 July 2018

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Mechanisms of beta cell death in diabetes: a minor role for CD95.

5 July 2018

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IFN-gamma action on pancreatic beta cells causes class I MHC upregulation but not diabetes

5 July 2018

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The nonobese diabetic mouse as a model of autoimmune diabetes: immune dysregulation gets the NOD.

5 July 2018

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Spontaneous autoimmune diabetes in monoclonal T cell nonobese diabetic mice

5 July 2018

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Nitric oxide primes pancreatic beta cells for Fas-mediated destruction in insulin-dependent diabetes mellitus

5 July 2018

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A mechanism for the major histocompatibility complex-linked resistance to autoimmunity

5 July 2018

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Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice

5 July 2018

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Requirement of Fas for the development of autoimmune diabetes in nonobese diabetic mice

5 July 2018

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Interferon-gamma increases the sensitivity of islets of Langerhans for inducible nitric-oxide synthase expression induced by interleukin 1.

5 July 2018

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Mouse islet cell lysis mediated by interleukin-1-induced Fas.

5 July 2018

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Acceleration of spontaneous diabetes in TCR-beta-transgenic nonobese diabetic mice by beta-cell cytotoxic CD8+ T cells expressing identical endogenous TCR-alpha chains

5 July 2018

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CD95-dependent bystander lysis caused by CD4+ T helper 1 effectors.

5 July 2018

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Viruses, cytokines, antigens, and autoimmunity

5 July 2018

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Identification of a population of CD4+ CTL that utilizes a perforin- rather than a Fas ligand-dependent cytotoxic mechanism.

5 July 2018

1 reference

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Lymphocyte-mediated cytotoxicity in vitro and in vivo: mechanisms and significance

5 July 2018

1 reference

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Mechanism and biological significance of CD4-mediated cytotoxicity

5 July 2018

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5 July 2018

1 reference

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Partial activation of CD8+ T cells by a self-derived peptide

5 July 2018

1 reference

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Loss of pancreatic islet tolerance induced by beta-cell expression of interferon-gamma

5 July 2018

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The role of CD4+ and CD8+ T cells in the destruction of islet grafts by spontaneously diabetic mice

5 July 2018

1 reference

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A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

5 July 2018

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Transgenes in autoimmunity

5 July 2018

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Expression of a tumor necrosis factor alpha transgene in murine pancreatic beta cells results in severe and permanent insulitis without evolution towards diabetes

5 July 2018

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Insulitis in transgenic mice expressing tumor necrosis factor beta (lymphotoxin) in the pancreas

5 July 2018

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CD95 and CD95-ligand expression in endocrine pancreas of NOD, NOR and BALB/c mice

5 July 2018

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12 December 2020

Inflammatory cytokine regulation of Fas-mediated apoptosis in thyroid follicular cells

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12 December 2020

Absolute requirement of macrophages for the development and activation of beta-cell cytotoxic CD8+ T-cells in T-cell receptor transgenic NOD mice

1 reference

12 December 2020

Transfer of diabetes in the NOD-scid mouse by CD4 T-cell clones. Differential requirement for CD8 T-cells

1 reference

12 December 2020

RIP-beta 2-microglobulin transgene expression restores insulitis, but not diabetes, in beta 2-microglobulin null nonobese diabetic mice

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12 December 2020

The role of Fas in autoimmune diabetes

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12 December 2020

Initiation of autoimmune diabetes in NOD/Lt mice is MHC class I-dependent

1 reference

12 December 2020

Fas and Fas ligand enhance the pathogenesis of experimental allergic encephalomyelitis, but are not essential for immune privilege in the central nervous system

1 reference

12 December 2020

Exclusive Expression of MHC Class II Proteins on CD45+ Cells in Pancreatic Islets of NOD Mice

1 reference

12 December 2020

Adoptive transfer of diabetes into immunodeficient NOD-scid/scid mice. Relative contributions of CD4+ and CD8+ T-cells from diabetic versus prediabetic NOD.NON-Thy-1a donors

1 reference

12 December 2020

Induction of type I diabetes by interferon-alpha in transgenic mice

1 reference

12 December 2020

Antigen-presenting cells in adoptively transferred and spontaneous autoimmune diabetes

1 reference

12 December 2020

Major histocompatibility complex class I molecules are required for the development of insulitis in non-obese diabetic mice

1 reference

12 December 2020

Beta 2-microglobulin-deficient NOD mice do not develop insulitis or diabetes

1 reference

12 December 2020

Major histocompatibility complex class I-deficient NOD-B2mnull mice are diabetes and insulitis resistant

1 reference

12 December 2020

Fas- and FasL-deficient mice are resistant to induction of autoimmune encephalomyelitis.

1 reference

12 December 2020

Autoantigen-independent deletion of diabetogenic CD4+ thymocytes by protective MHC class II molecules

1 reference

12 December 2020

Evidence that beta cell death in the nonobese diabetic mouse is Fas independent

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI8185

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10683375%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10683375%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

1 reference