The IFN-γ-inducible GTPase, Irga6, protects mice against Toxoplasma gondii but not against Plasmodium berghei and some other intracellular pathogens (Q33940781)

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English	The IFN-γ-inducible GTPase, Irga6, protects mice against Toxoplasma gondii but not against Plasmodium berghei and some other intracellular pathogens	scientific article

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PubMed publication ID

30 July 2017

The IFN-γ-inducible GTPase, Irga6, protects mice against Toxoplasma gondii but not against Plasmodium berghei and some other intracellular pathogens (English)

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Europe PubMed Central

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30 July 2017

Toxoplasma gondii

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Plasmodium berghei

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Jonathan Charles Howard

22

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30 July 2017

Olaf Utermöhlen

12

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Olaf Utermöhlen

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30 July 2017

Esther von Stebut

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Esther von Stebut

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Oliver Liesenfeld

1

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Oliver Liesenfeld

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Thorsten Buch

9

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Toni Aebischer

8

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Maria Manuel Dias da Mota

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Maria M Mota

19

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Ari Waisman

10

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Stefan Kaufmann

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Stefan H E Kaufmann

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Stephanie Könen-Waisman

20

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Stephanie Könen-Waisman

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30 July 2017

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Achim Hoerauf

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Christian Bogdan

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Christian Bogdan

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16

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Sabine Specht

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30 July 2017

Michael Saeftel

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Michael Saeftel

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30 July 2017

author name string

Oliver Liesenfeld

1

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30 July 2017

Iana Parvanova

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30 July 2017

Jens Zerrahn

3

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30 July 2017

Seong-Ji Han

4

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30 July 2017

Frederik Heinrich

5

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30 July 2017

Melba Muñoz

6

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30 July 2017

Frank Kaiser

7

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30 July 2017

Gaby Reichmann

11

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30 July 2017

Esther von Stebut

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30 July 2017

Friederike D von Loewenich

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30 July 2017

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publication date

17 June 2011

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30 July 2017

6

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30 July 2017

6

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30 July 2017

e20568

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30 July 2017

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Creative Commons Attribution 4.0 International

17 June 2011

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April 2022 Public Data File from Crossref

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Phosphorylation of mouse immunity-related GTPase (IRG) resistance proteins is an evasion strategy for virulent Toxoplasma gondii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117789

28 July 2018

The immunity-related GTPases in mammals: a fast-evolving cell-autonomous resistance system against intracellular pathogens

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The mouse resistance protein Irgm1 (LRG-47): a regulator or an effector of pathogen defense?

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28 July 2018

A dedicated promoter drives constitutive expression of the cell-autonomous immune resistance GTPase, Irga6 (IIGP1) in mouse liver

1 reference

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28 July 2018

IFN-gamma-inducible Irga6 mediates host resistance against Chlamydia trachomatis via autophagy

1 reference

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28 July 2018

Disruption of the Toxoplasma gondii parasitophorous vacuole by IFNgamma-inducible immunity-related GTPases (IRG proteins) triggers necrotic cell death

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28 July 2018

Regulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondii

1 reference

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28 July 2018

Chlamydia muridarum evades growth restriction by the IFN-gamma-inducible host resistance factor Irgb10.

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28 July 2018

IRG proteins: key mediators of interferon-regulated host resistance to intracellular pathogens

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28 July 2018

Disruption of Toxoplasma gondii parasitophorous vacuoles by the mouse p47-resistance GTPases.

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28 July 2018

The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage

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Chlamydial IFN-gamma immune evasion is linked to host infection tropism

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Mechanisms regulating the positioning of mouse p47 resistance GTPases LRG-47 and IIGP1 on cellular membranes: retargeting to plasma membrane induced by phagocytosis

1 reference

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28 July 2018

1 reference

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28 July 2018

Interleukin 1alpha promotes Th1 differentiation and inhibits disease progression in Leishmania major-susceptible BALB/c mice

1 reference

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The function of gamma interferon-inducible GTP-binding protein IGTP in host resistance to Toxoplasma gondii is Stat1 dependent and requires expression in both hematopoietic and nonhematopoietic cellular compartments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117789

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Immunopathogenesis of cerebral toxoplasmosis

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Inactivation of LRG-47 and IRG-47 reveals a family of interferon gamma-inducible genes with essential, pathogen-specific roles in resistance to infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117789

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Toxoplasma gondii: from animals to humans

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Pathogen-specific loss of host resistance in mice lacking the IFN-gamma-inducible gene IGTP

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Differential development of Toxoplasma gondii in neural cells

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Immune and inflammatory responses in the CNS: modulation by astrocytes

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117789

28 July 2018

Two families of GTPases dominate the complex cellular response to IFN-gamma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117789

28 July 2018

Regulation and function of T-cell-mediated immunity during Toxoplasma gondii infection.

1 reference

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How cells respond to interferons

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Safe haven: the cell biology of nonfusogenic pathogen vacuoles.

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Identification of a novel GTPase, the inducibly expressed GTPase, that accumulates in response to interferon gamma

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Importance of endogenous IFN-gamma for prevention of toxoplasmic encephalitis in mice.

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Host resistance in the brain against Toxoplasma gondii

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TCR V beta 8+ T cells prevent development of toxoplasmic encephalitis in BALB/c mice genetically resistant to the disease

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Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole

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10.1371/JOURNAL.PONE.0020568

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Europe PubMed Central

PubMed publication ID

30 July 2017

2011PLoSO...620568L

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

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