VX680/MK-0457, a potent and selective Aurora kinase inhibitor, targets both tumor and endothelial cells in clear cell renal cell carcinoma. (Q33942098)

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6 February 2020

title

VX680/MK-0457, a potent and selective Aurora kinase inhibitor, targets both tumor and endothelial cells in clear cell renal cell carcinoma (English)

1 reference

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6 February 2020

0 references

10

Bin Tean Teh

1 reference

PubMed publication ID

30 July 2017

Yan Li

1

1 reference

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6 February 2020

Zhong-Fa Zhang

2

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Jindong Chen

3

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6 February 2020

Dan Huang

4

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6 February 2020

Yan Ding

5

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6 February 2020

Min-Han Tan

6

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6 February 2020

Chao-Nan Qian

7

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6 February 2020

James H Resau

8

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Hyung Kim

9

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6 February 2020

Bin Tean Teh

10

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6 February 2020

language of work or name

English

0 references

publication date

20 May 2010

1 reference

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American Journal of Translational Research

6 February 2020

published in

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6 February 2020

volume

2

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6 February 2020

issue

3

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6 February 2020

page(s)

296-308

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6 February 2020

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Dual degradation of aurora A and B kinases by the histone deacetylase inhibitor LBH589 induces G2-M arrest and apoptosis of renal cancer cells.

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28 July 2018

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28 July 2018

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28 July 2018

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The Aurora kinase inhibitor VX-680 induces endoreduplication and apoptosis preferentially in cells with compromised p53-dependent postmitotic checkpoint function

28 July 2018

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Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data

28 July 2018

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Aurora-A abrogation of p53 DNA binding and transactivation activity by phosphorylation of serine 215.

28 July 2018

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VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo

28 July 2018

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The cellular geography of aurora kinases

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Exploration, normalization, and summaries of high density oligonucleotide array probe level data

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The Aurora kinases: role in cell transformation and tumorigenesis

28 July 2018

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A comparison of normalization methods for high density oligonucleotide array data based on variance and bias

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Mitotic phosphorylation of histone H3: spatio-temporal regulation by mammalian Aurora kinases

28 July 2018

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GSK1070916, a potent Aurora B/C kinase inhibitor with broad antitumor activity in tissue culture cells and human tumor xenograft models.

28 July 2018

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Clinical effect and future considerations for molecularly-targeted therapy in renal cell carcinoma

29 October 2018

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Inhibition of MAPK kinase signaling pathways suppressed renal cell carcinoma growth and angiogenesis in vivo.

29 October 2018

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29 October 2018

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Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53.

29 October 2018

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Summaries of Affymetrix GeneChip probe level data

29 October 2018

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29 October 2018

Identifiers

1 reference

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6 February 2020

PubMed publication ID

20589168

1 reference